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Compound could play a novel role in halting spread of pancreatic cancer

In early test tube and mouse studies, investigators at Johns Hopkins Medicine and the Johns Hopkins Kimmel Cancer Center have found that nonmuscle myosin IIC (MYH14), a protein activated in response to mechanical stress, helps promote metastatic behavior in pancreatic cancer cells, and that the compound 4-hydroxyacetophenone (4-HAP), known to stiffen myosin IIC-containing cells, can send it into overdrive, overwhelming the ability of cells to invade nearby tissue.

18 Sep 2019

Could drinking a small amount of alcohol everyday be good for type 2 diabetes?

A new meta-analysis suggests that people with type 2 diabetes may benefit from light-to-moderate drinking, which could have a positive effect on blood glucose and fat metabolism.

18 Sep 2019

Concerns over GM mosquitoes released in Brazil

A field experiment that released genetically modified mosquitoes in Brazil to control natural populations of the insect may have had unintended consequences.

18 Sep 2019

Alarming number of life-threatening heart infections related to drug abuse

As the nationwide opioid epidemic continues, more young people are developing a life-threatening heart infection that can result from drug abuse.

18 Sep 2019

A vegan diet could boost gut microbes that aid weight loss

Switching to a vegan diet could help people lose nearly one pound in weight every week and significantly reduce their risk for diabetes, say researchers.

18 Sep 2019

Low BMI with abdominal obesity linked to poor outcomes among Asian patients with heart failure

Having a lower body-mass index, but also with having a higher waist-to-height ratio, is associated with worse outcomes among Asian patients with heart failure, according to a study published September 24 in the open-access journal PLOS Medicine by Carolyn Lam of the National Heart Centre Singapore, and colleagues.

From PLOS ONE 18 Sep 2019

Patients with non-Hodgkin's lymphoma may benefit from radiation, experience reduced side effects

Treating non-Hodgkin's lymphoma patients with radiation therapy as an additional treatment while they wait for their CAR T cells to be manufactured may reduce the risk of CAR T therapy side effects once it is administered, according to a new study from researchers in the Abramson Cancer Center at the University of Pennsylvania.

18 Sep 2019

New peptides improve memory in mice with Alzheimer’s

Alzheimer’s disease (AD) affects over 44 million people the world over. But now, neurologist Jack Jhamandas and his team have found two short peptides which, on daily injection into mice with symptoms of AD for just five weeks, led to a significant improvement.

18 Sep 2019

Exercise may delay brain deterioration in people at high risk for Alzheimer's

Exercising several times a week may delay brain deterioration in people at high risk for Alzheimer's disease, according to a study that scientists say merits further research to establish whether fitness can affect the progression of dementia.

18 Sep 2019

New ultrasound technique can help identify risk and treatment for osteoporosis

A new ultrasound technique provides a non-invasive way of assessing bone structure on the microscale. Researchers hope to fine-tune the technique for use in assessing osteoporosis risk and treatment.

18 Sep 2019

Researchers aim to develop handheld device for diagnosing skin cancer

Even the best dermatologists can't diagnose skin cancer by eye, relying on magnifying glasses to examine suspicious blemishes and scalpels to cut tissue for analysis.

18 Sep 2019

Study: Gene editing may correct genetic mutation responsible for Duchenne muscular dystrophy

Duchenne muscular dystrophy (DMD) is a rare but devastating genetic disorder that causes muscle loss and physical impairments.

18 Sep 2019

New technology helps trace the origin of Huntington's disease

The first signs of Huntington's, an inherited disease that slowly deteriorates bodies and minds, don't typically surface until middle age.

18 Sep 2019

Next phase of innovative decision support program may lead to better health and care

The Digital Health and Care Institute is working in collaboration with the Scottish Government to launch the next research and development phase of the innovative decision support program.

18 Sep 2019

IMRT and cisplatin treatment meets acceptability criteria for PFS and swallowing-related QOL

Results of the NRG Oncology clinical trial NRG-HN002 indicated that the combination of intensity-modulated radiotherapy (IMRT) and cisplatin was able to meet acceptability criteria for progression-free survival (PFS) and swallowing-related quality of life for patients who have p16-positive, non-smoking-associated oropharyngeal cancer.

18 Sep 2019

Rutgers cardiologist recommends individualized treatment with aspirin for primary prevention of CVD

A nationally recognized Rutgers cardiologist recommends that aspirin be used as primary prevention for cardiovascular disease only with select patients, saying that the scientific evidence is too diverse to support a one-size-fits-all approach.

17 Sep 2019

Studying underlying electrical causes of arrhythmias

Despite advances in medical imaging, the mechanisms leading to the irregular contractions of the heart during heart rhythm disorders remain poorly understood.

17 Sep 2019

Study shows how a toxin produced by algal blooms in saltwater may cause ALS

Can a computer be used to explain why an environmental toxin might lead to neurodegenerative disease? According to Penn State College of Medicine researchers, a computer generated-simulation allowed them to see how a toxin produced by algal blooms in saltwater might cause Amyotrophic Lateral Sclerosis.

17 Sep 2019

Improving care and educational outreach for lupus patients

A new grant will allow MUSC doctors and researchers to test several ideas for improving care and outreach to people with lupus or at risk of developing the autoimmune disease.

17 Sep 2019

New results revealed from pilot stem cell study for stroke

Researchers led by Sean I. Savitz, MD, reported today in the journal Stem Cells that bone marrow cells used to treat ischemic stroke in an expanded Phase I trial were not only safe and feasible, but also resulted in enhanced recovery compared to a matched historical control group.

17 Sep 2019