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Link between COVID-19 severity and microbiome of saliva and nasopharynx

In a recent study posted to the bioRxiv* preprint server, researchers profiled the salivary and nasopharyngeal microbiomes of coronavirus disease 2019 (COVID-19) patients and determined the association between the microbiomes and COVID-19 severity.

6 Jun 2022

Safety and efficacy of SCB-2019 COVID vaccine candidate as a ChAdOx1-S booster

In a recent study posted to the medRxiv* pre-print server, researchers evaluated the immunogenicity of booster doses of alum-adjuvanted SCB-2019 vaccine candidate's three formulations.

6 Jun 2022

COVID-19's economic impact on healthcare systems, societies, and the population

In a recent study review posted to the medRxiv* preprint server, researchers evaluated the economic and medical costs incurred due to the coronavirus disease 2019 (COVID-19) pandemic.

6 Jun 2022

CRISPR-based diagnostics for SARS-CoV-2 detection

In a recent study posted to the Journal of Biochemical and Molecular Toxicology, researchers reviewed clustered regularly interspaced short palindromic repeats (CRISPR)-based diagnostics for detecting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

6 Jun 2022

Trial of peptide-centered SARS-CoV-2 T-cell activator in B-cell deficient individuals

A recent phase 1/2 study under review at the Nature Portfolio journal and posted to the Research Square* preprint server demonstrated that a peptide-centered severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) T-cell activator, CoVac-1, was efficient in B-cell deficient people.

6 Jun 2022

Weight loss with bariatric surgery associated with lower risk of cancer and cancer-related mortality

A Cleveland Clinic study shows that among adults with obesity, weight loss achieved with bariatric surgery was associated with a 32% lower risk of developing cancer and a 48% lower risk of cancer-related death compared with adults who did not have the surgery.

3 Jun 2022

Researchers evaluate how hundreds of different mutations impact key function of breast cancer gene

Inherited mutations in the BRCA1 gene can significantly increase a person's risk of breast and ovarian cancer - but not every mutation in the gene is harmful.

3 Jun 2022

Pandemic-era changes to prescribing opioid use disorder treatment improved treatment outcomes

Pandemic-era changes to prescribing guidelines for the lifesaving drug buprenorphine led to improved treatment outcomes for patients with opioid use disorder in Philadelphia, according to a recently published study in the journal Drug and Alcohol Dependence Reports from researchers at Drexel University's Dornsife School of Public Health.

3 Jun 2022

Researchers repurpose a cancer drug for the treatment of neuroinflammatory diseases

The repurposing of FDA-approved drugs for alternative diseases is a faster way of bringing new treatments into the clinic.

3 Jun 2022

Molecular 'connector' may underlie gender differences in cocaine’s effects, mice study shows

Scientists have long known that cocaine works by latching on to molecular connectors on the surface of brain cells, allowing dopamine, a chemical that promotes feelings of pleasure and reward, to accumulate in the space between brain cells.

3 Jun 2022

Exploring the effectiveness of various treatments in people with axial spondyloarthritis

axSpA is a chronic inflammatory rheumatic disease that mainly affects the spine and sacroiliac joints. It can cause significant pain and disability.

3 Jun 2022

Researchers identify predictive biomarkers to fight against non-small cell lung cancer

In a recent study, researchers at the University of Missouri are identifying new minimally invasive biomarkers to develop a blood test for early detection of non-small cell lung cancer (NSCLC), one of two main types of lung cancer.

3 Jun 2022

Study uncovers differences in genetic mutations between younger and older breast cancer patients

Women younger than 40 years of age with advanced breast cancer often suffer from more aggressive disease and worse prognoses than their older counterparts.

3 Jun 2022

Growing up in unsafe neighborhoods may lead to poorer sleep in adulthood

A recent study of Black women found that growing up in an unsafe neighborhood was associated with poorer sleep in adulthood.

3 Jun 2022

Community's sleep health predicts children's opportunities for positive growth and success

A community's sleep health is the most significant health predictor of children's opportunities for positive growth and success, according to an analysis to be presented at SLEEP 2022.

3 Jun 2022

Most COVID-19 survivors report lingering fatigue and sleep disturbances

Nearly all patients who recovered from COVID-19 report lingering fatigue, while half experience sleep disturbances, according to a recent analysis from Cleveland Clinic. Researchers found that race, obesity, and mood disorders are contributors.

3 Jun 2022

New immunotherapy mechanism can block spontaneous breast carcinogenesis

Researchers have discovered the mechanism by which specific immune cells can block breast cancer development and even suppress a developed tumor.

3 Jun 2022

Study reveals significant decline in breast, cervical, colorectal cancer screenings due to COVID-19 pandemic

New findings led by researchers at the American Cancer Society (ACS) show the number of women in the United States who reported having a recent (in the past year) breast cancer or cervical cancer screening dropped by 2.13 million (6%) and 4.47 million (11%) respectively in 2020 compared to 2018.

3 Jun 2022

Fecal Microbiota Transplantation found to be an optimal cost-effective treatment for recurrent C. difficile infection

Research recently published in Clinical Infectious Diseases from the University of Minnesota Medical School has found that Fecal Microbiota Transplantation, or FMT, is an optimal cost-effective treatment for first recurrent Clostridioides difficile infection, or CDI or C-Diff.

3 Jun 2022

Biodegradable piezoelectric film could help regenerate the native cartilage after knee damage

Osteoarthritis – a painful condition that results from the deterioration of the cartilage in our joints – affects millions of people worldwide.

3 Jun 2022

Medical Research News

Link between COVID-19 severity and microbiome of saliva and nasopharynx

Safety and efficacy of SCB-2019 COVID vaccine candidate as a ChAdOx1-S booster

COVID-19's economic impact on healthcare systems, societies, and the population

CRISPR-based diagnostics for SARS-CoV-2 detection

Trial of peptide-centered SARS-CoV-2 T-cell activator in B-cell deficient individuals

Weight loss with bariatric surgery associated with lower risk of cancer and cancer-related mortality

Researchers evaluate how hundreds of different mutations impact key function of breast cancer gene

Pandemic-era changes to prescribing opioid use disorder treatment improved treatment outcomes

Researchers repurpose a cancer drug for the treatment of neuroinflammatory diseases

Molecular 'connector' may underlie gender differences in cocaine’s effects, mice study shows

Exploring the effectiveness of various treatments in people with axial spondyloarthritis

Researchers identify predictive biomarkers to fight against non-small cell lung cancer

Study uncovers differences in genetic mutations between younger and older breast cancer patients

Growing up in unsafe neighborhoods may lead to poorer sleep in adulthood

Community's sleep health predicts children's opportunities for positive growth and success

Most COVID-19 survivors report lingering fatigue and sleep disturbances

New immunotherapy mechanism can block spontaneous breast carcinogenesis

Study reveals significant decline in breast, cervical, colorectal cancer screenings due to COVID-19 pandemic

Fecal Microbiota Transplantation found to be an optimal cost-effective treatment for recurrent C. difficile infection

Biodegradable piezoelectric film could help regenerate the native cartilage after knee damage

Membrane proteins in focus: Turning high-risk targets into routine workflows

How metabolic phenotyping can detect viral infections in minutes

Directed enzyme evolution and the Nobel Prize: Making enzymes evolve in the lab

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