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Drug combo delivered in a nanoparticle formulation extends the survival of mice with medulloblastoma

UNC Lineberger Comprehensive Cancer Center researchers have demonstrated that a novel combination of two drugs that act as targeted inhibitors, delivered in a nanoparticle formulation, extend the survival of mice with medulloblastoma.

27 Jan 2022

French project takes an extra step in the development of nasal vaccine candidate against COVID-19

The development of a protein vaccine candidate for nasal administration has taken another step. Led by the BioMAP research team, from the Infectiology and Public Health (ISP) joint research unit run by INRAE and the Université de Tours, this project, supported by the Ministry of Higher Education, Research and Innovation, and accompanied by the ANRS | Maladies infectieuses émergentes, is moving up a gear.

27 Jan 2022

UofL professor wins $6.7 million grant to investigate how metals cause lung cancer

For nearly three decades, John Pierce Wise Sr. has investigated the connection between exposure to metals and cancer, working both in the lab and in the field, reporting significant discoveries about the effects of metals on chromosomes in lung cancer and how those effects differ in humans and in whales.

27 Jan 2022

Study highlights the risk of kidney disease and obesity in people with type 1 diabetes

People with type 1 diabetes should be screened regularly for obesity and chronic kidney disease, according to a study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

27 Jan 2022

Risk of long COVID-19 predicted by immunoglobulin signature

In a new study published in the journal Nature Communications, scientists studied COVID-19 patients and found that the immunoglobulin (Ig) signature can predict the risk of PACS independently of the time point of blood sampling.

27 Jan 2022

Following heart-healthy lifestyle behaviors can support good brain health

The same risk factors that contribute to making heart disease the leading cause of death worldwide also impact the rising global prevalence of brain disease, including stroke, Alzheimer's disease and dementia, according to the American Heart Association's Heart Disease and Stroke Statistics - 2022 Update, published today in the Association's flagship, peer-reviewed journal Circulation.

27 Jan 2022

National identities play a significant and positive role in battling COVID-19 pandemic

Identification with one's nation predicts both greater engagement with public health behaviors, such as masking and social distancing, and support for public health policies, finds an analysis of attitudes across 67 countries.

27 Jan 2022

Strict COVID-19 lockdown policies helped reduce air pollution levels and death rates in Europe

Strict COVID-19 lockdown policies such as workplace closures in European cities reduced levels of air pollution and the number of associated deaths, according to new estimates published in Nature's Scientific Reports.

27 Jan 2022

Targeting SARS-CoV-2 M protein may help ease severity of COVID-19

A new study, published on the medRxiv preprint server, focused on the production of human CD4+ T cell lines (TCLs), reactive to either S or M protein, and analyzed if the S and M structural proteins had intrinsic differences in driving antigen-specific CD4+ T cell responses.

27 Jan 2022

Cancer-causing chemical inside the car cannot be dusted or wiped way, research says

It is unlikely that a cancer-causing chemical inside your car can be dusted or wiped way, according to new UC Riverside research.

27 Jan 2022

COVID-19 vaccination does not affect fertility outcomes in patients undergoing in-vitro fertilization

Vaccination against COVID-19 did not affect fertility outcomes in patients undergoing in-vitro fertilization (IVF), a new study has found.

27 Jan 2022

Music therapy can be an attractive option to manage menopause symptoms and depressed mood

As researchers continue to seek effective treatment options for menopause symptoms as alternatives to proven pharmacologic solutions, a number of innovative therapies have been shown to improve symptoms.

27 Jan 2022

Death rates from ovarian cancer are predicted to fall by 2022 in EU countries

Death rates from ovarian cancer are predicted to fall by 17% in the UK and by 7% in EU countries in 2022 compared to 2017, according to new research published in the leading cancer journal Annals of Oncology today (Wednesday).

27 Jan 2022

Omicron RBD mutations increase ACE2 binding and reduce antibody sensitivity

In a study conducted at the Florida International University, USA, scientists have investigated the impact of spike receptor-binding domain (RBD) mutations of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) omicron variant on its interaction with human angiotensin-converting enzyme 2 (ACE2).

26 Jan 2022

Recipients of inactivated COVID-19 vaccine (CoronaVac) can be successfully boosted with different vaccines

In the recently published study in The Lancet, first-authored by Dr. Sue Ann Costa Clemens from the University of Oxford in the United Kingdom and the University of Siena in Italy, a comprehensive analysis has been pursued on the immunogenicity and safety of both homologous and heterologous boosting after receiving the inactivated vaccine CoronaVac.

26 Jan 2022

Study helps understand how smoking can lead to an increased risk of heart attacks

Smoking cigarettes may increase the risk of a heart attack by activating a gene that affects blood clotting, according to a new study by scientists at the University of Bristol.

26 Jan 2022

Regular physical activity lowers type 2 diabetes risk by changing the body's metabolite profile

Regular physical activity significantly changes the body's metabolite profile, and many of these changes are associated with a lower risk of type 2 diabetes, a new study from the University of Eastern Finland shows.

26 Jan 2022

Urinary proteomic COV50 marker accurately predicts adverse COVID-19 outcomes

The researchers described COV50, a urinary biomarker, that can predict death and disease progression in COVID-19.

26 Jan 2022

Immunosuppressed patients can benefit from COVID-19 booster vaccination, study shows

Patients under immunosuppressive therapy, who do not respond to primary COVID-19 vaccination, have an increased risk for severe COVID-19 disease courses. Until now, it was not clear whether those patients at risk can benefit from an additional booster vaccination.

26 Jan 2022

T-cell apoptosis linked to poor prognosis among COVID-19 patients

Researchers assess the probability of T-cell apoptosis in patients with severe COVID-19 who were admitted to the hospital.

26 Jan 2022

Medical Research News

Drug combo delivered in a nanoparticle formulation extends the survival of mice with medulloblastoma

French project takes an extra step in the development of nasal vaccine candidate against COVID-19

UofL professor wins $6.7 million grant to investigate how metals cause lung cancer

Study highlights the risk of kidney disease and obesity in people with type 1 diabetes

Risk of long COVID-19 predicted by immunoglobulin signature

Following heart-healthy lifestyle behaviors can support good brain health

National identities play a significant and positive role in battling COVID-19 pandemic

Strict COVID-19 lockdown policies helped reduce air pollution levels and death rates in Europe

Targeting SARS-CoV-2 M protein may help ease severity of COVID-19

Cancer-causing chemical inside the car cannot be dusted or wiped way, research says

COVID-19 vaccination does not affect fertility outcomes in patients undergoing in-vitro fertilization

Music therapy can be an attractive option to manage menopause symptoms and depressed mood

Death rates from ovarian cancer are predicted to fall by 2022 in EU countries

Omicron RBD mutations increase ACE2 binding and reduce antibody sensitivity

Recipients of inactivated COVID-19 vaccine (CoronaVac) can be successfully boosted with different vaccines

Study helps understand how smoking can lead to an increased risk of heart attacks

Regular physical activity lowers type 2 diabetes risk by changing the body's metabolite profile

Urinary proteomic COV50 marker accurately predicts adverse COVID-19 outcomes

Immunosuppressed patients can benefit from COVID-19 booster vaccination, study shows

T-cell apoptosis linked to poor prognosis among COVID-19 patients

Advancing Menopause Care: Non-Hormonal Treatments for Vasomotor Symptoms

Building quality into drug development for safer, faster medicines

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

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