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Immunogenicity and safety of COVID-19 subunit vaccine Nanocovax in animal models

Researchers have developed Nanocovax, a COVID-19 subunit vaccine based on recombinant protein technology to produce the extracellular (soluble) portion of the S protein of SARS-CoV-2.

9 Dec 2021

Sleeping people respond to wind farm and road traffic noise, study shows

Sleeping people respond to both wind farm noise and road traffic noise, but not usually enough to wake them up, according to new Flinders University research.

9 Dec 2021

UVA researchers uncover common link between lupus and macular degeneration

University of Virginia School of Medicine researchers have made a discovery linking lupus, a potentially debilitating autoimmune disorder, and macular degeneration, a leading cause of blindness.

9 Dec 2021

Older people taking anxiety drugs and antidepressants more likely to suffer postoperative delirium

Older people taking a drug used to treat anxiety and insomnia – nitrazepam – as well as those on antidepressants, are twice as likely to suffer postoperative delirium after hip and knee surgery, a new Australian study has found.

9 Dec 2021

Study uncovers differences in one-carbon and energy metabolism between episodic, chronic depression

A study carried out in the University of Eastern Finland discovered differences in one-carbon and energy metabolism between episodic and chronic depression.

9 Dec 2021

High quality products for cultured meat research

AMSBIO has announced a new range of kits, media and reagents to assist in the development of cultured meat products - an exciting new area of food technology.

From AMS Biotechnology 9 Dec 2021

Sugar-binding pockets in N-terminal domain may increase SARS-CoV-2 infectivity

The N-terminal domain has a fold that can bind sugar, and new research led by Jonathan Lees from Oxford Brookes University found the sugar-binding pockets near the N-terminal domain help to increase viral infectivity. Furthermore, the findings show that the SARS-CoV-2 sugar-binding pockets are evolving with added loops observed in the pockets of new variants.

9 Dec 2021

Mass-spectrometry and PCR testing identifies various targets related to SARS-CoV-2 VOCs

New research posted to the medRxiv* preprint server suggests that the Agena MassARRAY SARS-CoV-2 Panel PCR test effectively detects a variety of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants.

9 Dec 2021

SARS-CoV-2 variants are evolving new ways to evade antibodies and vaccines

Continued replication of severe acute respiratory syndrome-associated coronavirus 2 (SARS-CoV-2) under selective pressure from natural and vaccine-induced immunity has led to the emergence of variants of concern (VOCs) with increased transmissibility or virulence.

8 Dec 2021

For most young people, COVID vaccine-related myocarditis is not serious

A new study published in the journal Circulation aimed to describe a large case series of suspected myocarditis temporally related with the COVID-19 vaccine in adolescents and young adults below 21 years of age across the United States and Canada.

8 Dec 2021

Neutralization antibodies elevated in nursing home residents after COVID-19 mRNA boosters

Researchers from the United States, in their recent study published on the preprint server medRxiv*, have evaluated the humoral responses to third vaccine dose in nursing home residents and healthcare workers (HCW) and found that that second booster (or third vaccine dose) significantly increased anti-spike, anti-receptor binding domain (RBD), and neutralization titers in almost all nursing home residents and HCW to considerably higher levels than what was attained after the completion of the initial two-dose vaccine series.

8 Dec 2021

Systemic sclerosis more common among Black children than previously thought

An immune disease that can damage vital organs – and is supposedly rare in young people – is more common than previously thought among Black children, a study suggests.

8 Dec 2021

High-dose intravenous iron reduces heart attacks in hemodialysis patients

A new paper in Cardiovascular Research, published by Oxford University Press, indicates that iron treatments may reduce heart attacks in patients experiencing kidney failure undergoing dialysis.

8 Dec 2021

Study identifies several proteins that protect against disease development

Inflammatory processes are associated with a large range of human diseases, including rheumatic diseases and allergies. Protein biomarkers are measurable molecules that can have a prognostic value in patients, be used to diagnose disease, or indicate severity of disease.

8 Dec 2021

Omicron binds to ACE2 with high affinity, enhancing its transmissibility and infectivity

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8 Dec 2021

Research provides new insights into debilitating cluster headaches

Debilitating cluster headaches commonly begin in childhood, but patients are not typically diagnosed until they are adults, according to research from The University of Texas Health Science Center at Houston.

8 Dec 2021

Routine immunization coverage declined in first year of COVID

A new study published on the medRxiv* preprint server investigated changes in RI coverage using two key indicators – diphtheria-tetanus-pertussis first-dose (DTP1) and third-dose (DTP3). DTP3 serves as a general marker for immunization system performance, while DTP1 is used as a proxy for inequity - quantifying Zero Dose (ZD) children––those that receive no childhood vaccinations

8 Dec 2021

Medical Research News

Immunogenicity and safety of COVID-19 subunit vaccine Nanocovax in animal models

Sleeping people respond to wind farm and road traffic noise, study shows

UVA researchers uncover common link between lupus and macular degeneration

Older people taking anxiety drugs and antidepressants more likely to suffer postoperative delirium

Study uncovers differences in one-carbon and energy metabolism between episodic, chronic depression

High quality products for cultured meat research

Sugar-binding pockets in N-terminal domain may increase SARS-CoV-2 infectivity

Mass-spectrometry and PCR testing identifies various targets related to SARS-CoV-2 VOCs

SARS-CoV-2 variants are evolving new ways to evade antibodies and vaccines

For most young people, COVID vaccine-related myocarditis is not serious

Neutralization antibodies elevated in nursing home residents after COVID-19 mRNA boosters

Systemic sclerosis more common among Black children than previously thought

High-dose intravenous iron reduces heart attacks in hemodialysis patients

Study identifies several proteins that protect against disease development

Omicron binds to ACE2 with high affinity, enhancing its transmissibility and infectivity

Research provides new insights into debilitating cluster headaches

Routine immunization coverage declined in first year of COVID

Study reveals trends in binge drinking among older U.S. men and women

Earlier screening for rare genetic mutation could lead to faster treatment for heart failure in Black Americans

Study examines the extent of medication-related harm in pediatric intensive care units

Advancing Drug Safety Assessment With AI, Predictive Modeling, and Human-Relevant Data

AI-powered analytics and experimental validation

Membrane proteins in focus: Turning high-risk targets into routine workflows

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