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Research highlights potentially life-saving screening for HR-HPV–driven head and neck cancers

Cancer causing high-risk human papillomaviruses (HR-HPV) are responsible for the rising incidence of HR-HPV–driven head and neck cancers (HNC), particularly oropharyngeal cancers (OPC, or throat cancers). Investigators have determined that HR-HPV DNA can be detected in saliva in most patients with HPV-driven OPC at the time of diagnosis. This work highlights a potentially life-saving screening program based on salivary HR-HPV DNA testing for early cancer detection and patient monitoring. Their findings appear in The Journal of Molecular Diagnostics, published by Elsevier.

22 Sep 2021

Compound extracted from orchid could be a potential treatment option for prostate cancer

Research led by the Centenary Institute has found that a compound extracted from a commonly cultivated orchid could be a potential new treatment option for prostate cancer.

22 Sep 2021

Study findings could lead to novel ways to overcome tumor resistance to immunotherapies

Cancer-fighting immune cells in patients with lung cancer whose tumors do not respond to immunotherapies appear to be running on a different "program" that makes them less effective than immune cells in patients whose cancers respond to these immune treatments, suggests a new study led by researchers at the Johns Hopkins Kimmel Cancer Center Bloomberg~Kimmel Institute for Cancer Immunotherapy.

22 Sep 2021

Healthy eating pattern improves weight, reduces cardiovascular disease risks in overweight children

A Cleveland Clinic-led research team found that statistically overweight children who followed a healthy eating pattern significantly improved weight and reduced a variety of cardiovascular disease risks.

22 Sep 2021

Children receiving living donor liver transplant less likely to experience organ rejection

In the United States alone, 500 children will need a liver transplant this year. While liver tissue can come from living or deceased donors, no studies have demonstrated which of these methods leads to better outcomes for children. In a new publication, researchers at Children's Hospital Los Angeles pooled published results from over 8,000 pediatric patients across four continents. The data reveal that children who receive living donor liver tissue for transplants are far less likely to experience serious complications like organ rejection.

22 Sep 2021

Study supports the implementation of Beckman Coulter’s MDW in emergency labs as initial test to detect sepsis

Beckman Coulter announced the results of a prospective study carried out across two European hospitals, which found that Monocyte Distribution Width, in combination with White Blood Cell Count with Differential, has the diagnostic accuracy to detect the risk of sepsis and severe infection upon patient presentation in A&E, particularly when assessed in patients with a lower likelihood of sepsis.

22 Sep 2021

Researchers identify distinctive biological markers for earlier detection of pregnancy risks

Researchers from Flinders University and the Robinson Research Institute at the University of Adelaide have identified distinctive biological markers that could improve the routine blood tests pregnant women already undergo and detect risks for pregnancy complications earlier than currently possible.

22 Sep 2021

Research pinpoints new therapeutic opportunity for ovarian clear cell carcinomas

Mutations in the ARID1A gene are present in more than 50% of ovarian clear cell carcinomas (OCCC), for which effective treatments are lacking. Scientists at The Wistar Institute discovered that loss of ARID1A function enhances a cellular stress response pathway that promotes survival of cancer cells, which become sensitive to pharmacological inhibition of this pathway. These findings were published online in Cancer Research, a journal of the American Association for Cancer Research, and point to a new therapeutic opportunity for this type of ovarian cancer for which new solutions are urgently needed.

22 Sep 2021

Researchers explore which types of brain activity support consciousness

Consciousness remains one of the brain's biggest mysteries. We know very little about how it emerges from activity within the brain, but most neuroscientists agree consciousness is dynamic in nature.

22 Sep 2021

Researchers devise guidelines for reporting mediation analyses of trials, observational studies

A new guideline has been developed to help scientists publish their research accurately and transparently. Published in JAMA, the AGReMA Statement (A Guideline for Reporting Mediation Analyses) provides recommendations for researchers who want to describe mediation analysis in their paper. Mediation analysis is primarily used to understand how an intervention works or why it does not.

22 Sep 2021

Young people with cancer face inequalities in fertility preservation services across the UK

Young people who survive cancer are at risk of missing out on the chance to have children in the future, due to inequalities in fertility preservation services across the UK, new research has found.

22 Sep 2021

Study reveals strong connection between infection rates and strains of authoritarianism

According to psychologists, in addition to our physiological immune system, we also have a behavioral one: an unconscious code of conduct that helps us stay disease-free, including fear and avoidance of unfamiliar - and so possibly infected - people.

22 Sep 2021

Study investigates if music can improve memory in people with Alzheimer's disease

The main goal of the study, named "The Mozart Effect and memory in patients with cognitive impairment (MEM-COG)", is to investigate whether music can be used to facilitate or enhance learning in those with mild cognitive impairment (MCI) or mild Alzheimer's disease (AD).

21 Sep 2021

Young people with cancer in the UK face funding lottery for fertility preservation services

Children and young people with cancer in the UK face something of a funding lottery for services to preserve their fertility, with specialist treatment centers heavily reliant on charities to stump up the cash needed, particularly in England, finds the first study of its kind, published online in the Archives of Disease in Childhood.

21 Sep 2021

Medical Research News

Research highlights potentially life-saving screening for HR-HPV–driven head and neck cancers

Compound extracted from orchid could be a potential treatment option for prostate cancer

Study findings could lead to novel ways to overcome tumor resistance to immunotherapies

Healthy eating pattern improves weight, reduces cardiovascular disease risks in overweight children

Children receiving living donor liver transplant less likely to experience organ rejection

Study supports the implementation of Beckman Coulter’s MDW in emergency labs as initial test to detect sepsis

Researchers identify distinctive biological markers for earlier detection of pregnancy risks

Research pinpoints new therapeutic opportunity for ovarian clear cell carcinomas

Researchers explore which types of brain activity support consciousness

Researchers devise guidelines for reporting mediation analyses of trials, observational studies

Young people with cancer face inequalities in fertility preservation services across the UK

Study reveals strong connection between infection rates and strains of authoritarianism

Study investigates if music can improve memory in people with Alzheimer's disease

Young people with cancer in the UK face funding lottery for fertility preservation services

Nemours receives $10.5 million NIH grant to support research in sickle cell disease

High-fat diet or genetically induced obesity can lead to loss of hair follicles

Delirium is highly likely in patients hospitalized for severe COVID-19

Those undergoing treatment for hematological malignancies show reduced immune response to COVID-19 vaccines

Severe tinnitus following SARS-CoV-2 infection

Oxford COVID vaccine technology has the potential to revolutionize cancer treatment

Advancing Menopause Care: Non-Hormonal Treatments for Vasomotor Symptoms

Building quality into drug development for safer, faster medicines

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

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