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Prior treatment may impact efficacy of ACT-TIL in patients with metastatic melanoma

Patients with metastatic melanoma that had relapsed on anti-PD-1 therapies or BRAF/MEK inhibitors did not respond as well to an investigational therapy that involves the adoptive cell transfer of tumor-infiltrating lymphocytes (ACT-TIL) as patients naïve to these treatments.

19 Aug 2021

HMGA1 plays role in gastric cancer cell proliferation and metastasis

Aging-US published "HMGA1 promotes gastric cancer growth and metastasis by transactivating SUZ12 and CCDC43 expression" which reported that HMGA1 is overexpressed in GC cells and the high expression of HMGA1 was correlated with worse survival in GC patients using a bioinformatics assay.

19 Aug 2021

Cognitive rehabilitation found to be effective in treating multiple sclerosis-related cognitive dysfunction

In a review of recent literature, a team of researchers from Kessler Foundation conclude that cognitive rehabilitation programs are efficacious in treating multiple sclerosis-related cognitive dysfunction, and urge clinicians to consider this low-cost, low-risk, yet effective treatment approach for their patients.

19 Aug 2021

Study reveals mechanism behind male infertility caused by autoimmune disease

Investigators have found that the absence of autoimmune regulator (Aire) in mice results in fertility problems similar to those affecting men with autoimmune polyendocrine syndrome type I (APS-1).

19 Aug 2021

Hidradenitis suppurativa: Discontinuation of adalimumab prior to surgery is not necessary

Hidradenitis suppurativa (Syn. Acneinversa) is one of the most troublesome and complicated skin diseases. The anti-inflammatory drug adalimumab can improve symptoms; however, patients also often have to undergo surgery.

19 Aug 2021

Research project identifies deficiencies in models used for assessing chemical safety at workplaces

A research project affiliated with the University of Helsinki's Institute for Atmospheric and Earth System Research has identified serious deficiencies in the Stoffenmanager and Advanced REACH Tool occupational exposure models used for assessing chemical safety and calls for the discontinuation of their use in statutory chemical safety assessment.

19 Aug 2021

Vaccines remain the most effective way to protect against COVID-19 Delta variant, study says

Obtaining two vaccine doses remains the most effective way to ensure protection against the COVID-19 Delta variant of concern dominant in the UK today, according to a study from the University of Oxford.

19 Aug 2021

Research uses mathematical modeling to find an equitable way for sharing vaccines between nations

New research from the University of Oxford and the UK Centre for Ecology & Hydrology, published today in Frontiers in Public Health, uses mathematical modeling to determine the most equitable way to share vaccines between nations.

19 Aug 2021

Existing drugs block or reduce SARS-CoV2 infection in cells

Since the beginning of the pandemic, researchers worldwide have been looking for ways to treat COVID-19. And while the COVID-19 vaccines represent the best measure to prevent the disease, therapies for those who do get infected remain in short supply.

19 Aug 2021

Vaccine quickly reduced COVID-19 infections among health care workers

A UC Davis Health retrospective study published recently in Infection Control and Hospital Epidemiology shows how quickly COVID-19 infections were reduced among health care workers when vaccines were first distributed late last year.

19 Aug 2021

Rare gene variant increases zoonotic H7N9 virus susceptibility in humans

Rare, single-nucleotide variants in the MX1 gene increase human susceptibility to zoonotic H7N9 avian influenza infection, according to a new study.

19 Aug 2021

Study shows an increase in home drinking during COVID-19 pandemic

During the COVID-19 pandemic months of March 2020 to September 2020, U.S. alcohol retail store sales increased compared to usual trends while food services and drinking places sales decreased markedly during the same period, according to a new study at Columbia University Mailman School of Public Health.

19 Aug 2021

Study highlights the importance of better face masks and good ventilation to mitigate COVID-19 indoors

A new study is highlighting a need for widespread use of better face masks and the importance of good ventilation to mitigate the spread of COVID-19 indoors.

19 Aug 2021

Two key brain functions may improve during aging

It's long been believed that advancing age leads to broad declines in our mental abilities. Now new research from Georgetown University Medical Center offers surprisingly good news by countering this view.

19 Aug 2021

Urine test for detecting chronic kidney disease is not used enough in high-risk groups, study suggests

Despite their higher risk of chronic kidney disease, people with hypertension or diabetes usually are not given a simple test for protein in the urine to screen for this potentially deadly disorder, according to a study led by researchers at Johns Hopkins Bloomberg School of Public Health.

19 Aug 2021

Medical Research News

Prior treatment may impact efficacy of ACT-TIL in patients with metastatic melanoma

HMGA1 plays role in gastric cancer cell proliferation and metastasis

Cognitive rehabilitation found to be effective in treating multiple sclerosis-related cognitive dysfunction

Study reveals mechanism behind male infertility caused by autoimmune disease

Hidradenitis suppurativa: Discontinuation of adalimumab prior to surgery is not necessary

Research project identifies deficiencies in models used for assessing chemical safety at workplaces

Vaccines remain the most effective way to protect against COVID-19 Delta variant, study says

Research uses mathematical modeling to find an equitable way for sharing vaccines between nations

Existing drugs block or reduce SARS-CoV2 infection in cells

Vaccine quickly reduced COVID-19 infections among health care workers

Rare gene variant increases zoonotic H7N9 virus susceptibility in humans

Study shows an increase in home drinking during COVID-19 pandemic

Study highlights the importance of better face masks and good ventilation to mitigate COVID-19 indoors

Two key brain functions may improve during aging

Urine test for detecting chronic kidney disease is not used enough in high-risk groups, study suggests

Frequent adolescent cannabis use may carry intergenerational risks, study finds

Small study suggests a mix-and-match COVID-19 booster produces robust antibody levels

SARS-CoV-2 antibodies found to neutralize bat coronavirus (RaTG13) in new study

How does the SARS-CoV-2 Delta variant’s spike drive membrane fusion and immunity evasion?

Children and young adults are frequently exposed to unsafe opioid prescriptions, study suggests

Advancing Menopause Care: Non-Hormonal Treatments for Vasomotor Symptoms

Building quality into drug development for safer, faster medicines

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

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