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Neurotransmitter orexin influences reward processing - associated with pleasure and reward pathways in the brain

Researchers at the University of Pennsylvania School of Medicine have discovered that the recently identified neurotransmitter orexin (also known as hypocretin) influences reward processing by activating neurons in the lateral hypothalamus region of the brain.

28 Aug 2005

Inflammation plays an important role in post-operative stroke

Duke University Medical Center researchers have discovered that patients who have two specific gene variants are more than three times as likely to suffer a stroke after heart surgery.

26 Aug 2005

New strategy to turn off the function of a special group of T cells to suppress immune response to tumors

A special stretch of genetic material may turn off the immune suppression that stymies attempts to fight cancer with a vaccine, said researchers at Baylor College of Medicine (BCM) at Houston.

26 Aug 2005

Stem cells with heart bypass surgery trial to begin

The University of Pittsburgh Medical Center (UPMC) has been granted approval by the U.S. Food and Drug Administration (FDA) to conduct a clinical trial to determine the safety and feasibility of injecting a patient's own bone marrow-derived stem cells directly into the heart during conventional heart bypass surgery.

25 Aug 2005

Psychological distress of parents of children with spina bifida

Parents of children with spina bifida suffer from more psychological distress than parents of able-bodied children. Research published in the open access journal BMC Pediatrics reveals that having a child with spina bifida (SB) has a negative effect on parents' psychological well-being.

25 Aug 2005

Protein snapin has potential as a drug target in therapies aimed at learning and memory disorders

Rutgers' Bonnie Firestein likens nerve cells to trees -- some are short and bushy with many branches while others are tall with a few branches coming out of one or two main trunks. Different branching patterns correlate with specific disorders and Firestein's quest is to discover how these dissimilar patterns come about and why.

25 Aug 2005

The role of antigenic drive and tumor-infiltrating accessory cells in the pathogenesis of Helicobacter-induced MALT lymphoma

Research led by Dr. Anne Mueller at Stanford University School of Medicine demonstrates that successful eradication of Helicobacter may not prevent future aggressive gastric lymphoma since resting B cells are left behind.

25 Aug 2005

Parts of the brain used in daydreaming are the same areas that fail in people who have Alzheimer's disease

Researchers who used five different medical imaging techniques to study the brain activity of 764 people, including those with Alzheimer's disease, those on the brink of dementia, and healthy individuals, have found that the areas of the brain that young, healthy people use when daydreaming are the same areas that fail in people who have Alzheimer's disease.

25 Aug 2005

Coronary angioplasty increases risk of developing Alzheimer's disease

Boston University School of Medicine (BUSM) researchers have discovered that patients who have either coronary artery bypass graft surgery or coronary angioplasty are at an increased risk of developing Alzheimer's disease.

25 Aug 2005

Stress does not appear to influence the outcome of IVF

New research from Sweden has shown that psychological stress does not appear to influence the outcome of IVF – good news for women who fear that the understandable anxiety that they suffer during fertility treatment might damage their chances of conceiving.

24 Aug 2005

Brain plays an important role in the maintenance of proper bone density

The results of this research, involving a study of the activity of the protein interleukin 1 in the brain, comprise not only a breakthrough in understanding the regulation of bone density by the brain but also hold promise for the development of future treatment for osteoporosis, say the researchers.

24 Aug 2005

New insight into how sunlight affects DNA

Chemists at Ohio State University have gained new insight into how sunlight affects DNA. And what they found overturns ideas about genetic mutation that originated decades ago.

24 Aug 2005

New drug that selectively blocks immune responses protects kidneys after transplant

In an international clinical trial, a new drug that selectively blocks immune responses has proved as effective in preventing acute kidney transplant rejection as cyclosporine, the standard anti-rejection treatment.

24 Aug 2005

Review on fetal pain creates controversy

A review of medical evidence, which has apparently found that fetuses don't feel pain until the final months of pregnancy, has created controversy and has presented a powerful challenge to abortion opponents.

24 Aug 2005

First human gene mutation that causes extreme farsightedness

Working with an Amish-Mennonite family tree, Johns Hopkins researchers at the Wilmer Eye Institute have discovered what appears to be the first human gene mutation that causes extreme farsightedness.

24 Aug 2005

Hundreds of identified genes involved in the pathophysiology of ulcerative colitis and Crohn disease

In a paper published in PLoS Medicine researchers from the German Genome Research Network have analysed the expression of thousands of genes from patients with inflammatory bowel disease (ulcerative colitis and Crohn disease) using a genome wide approach to produce a comprehensive picture of which genes are activated in these conditions.

24 Aug 2005

Mouse model of Rett Syndrome displays reduced cortical activity

Sacha Nelson of Brandeis University in Waltham, MA and Rudolf Jaenisch of the Whitehead Institute of Biomedical Research in Cambridge, MA and their colleagues report online in the Proceedings of the National Academy of Sciences Early Edition that spontaneous neuronal activity is reduced in the cortex of a knockout mouse model for the childhood neurodevelopmental disorder, Rett Syndrome.

23 Aug 2005

A preoperative testing strategy may help determine stage of lung cancer more accurately

A preoperative testing strategy combining two procedures may help improve the accuracy of determining the stage of lung cancer, according to an article in the August 24/31 issue of JAMA: The Journal of the American Medical Association.

23 Aug 2005

Use of general anesthesia for heroin detoxification offers no benefit when compared to two other methods

The use of general anesthesia for heroin detoxification offers no benefit when compared to two other methods, and is associated with several potentially life-threatening adverse events, according to an article in the August 24/31 issue of JAMA: The Journal of the American Medical Association.

23 Aug 2005

Benefits of MAO-B inhibitors are small but may be worthwhile in some patients with early Parkinson's disease

A class of drugs known as MAO-B inhibitors may be effective in improving motor symptoms in people with early Parkinson's disease and may delay the need for treatment with other drugs, according to a new systematic review of current evidence.

23 Aug 2005

Medical Research News

Neurotransmitter orexin influences reward processing - associated with pleasure and reward pathways in the brain

Inflammation plays an important role in post-operative stroke

New strategy to turn off the function of a special group of T cells to suppress immune response to tumors

Stem cells with heart bypass surgery trial to begin

Psychological distress of parents of children with spina bifida

Protein snapin has potential as a drug target in therapies aimed at learning and memory disorders

The role of antigenic drive and tumor-infiltrating accessory cells in the pathogenesis of Helicobacter-induced MALT lymphoma

Parts of the brain used in daydreaming are the same areas that fail in people who have Alzheimer's disease

Coronary angioplasty increases risk of developing Alzheimer's disease

Stress does not appear to influence the outcome of IVF

Brain plays an important role in the maintenance of proper bone density

New insight into how sunlight affects DNA

New drug that selectively blocks immune responses protects kidneys after transplant

Review on fetal pain creates controversy

First human gene mutation that causes extreme farsightedness

Hundreds of identified genes involved in the pathophysiology of ulcerative colitis and Crohn disease

Mouse model of Rett Syndrome displays reduced cortical activity

A preoperative testing strategy may help determine stage of lung cancer more accurately

Use of general anesthesia for heroin detoxification offers no benefit when compared to two other methods

Benefits of MAO-B inhibitors are small but may be worthwhile in some patients with early Parkinson's disease

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Bioprocess Efficiency with Cell Density Monitoring

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