Cancer News and Research

Latest Cancer News and Research

Higher doses of CAR-T therapy achieve better survival rates for young patients with hard-to-treat B-ALL

Young people who received doses of tisagenlecleucel, a chimeric antigen receptor T cell (CAR-T) therapy, at the higher end of the FDA-approved dosing range had significantly better survival rates at one year compared with those who received lower doses within this range, according to research published today in Blood Advances.

8 Aug 2022

First Phase II study of immunotherapy combined with curative radiotherapy for unresectable locally advanced NSCLC

Researchers from Japan today reported that the first phase II study to evaluate the efficacy and safety of durvalumab and concurrent curative radiation therapy for PD-L1-positive unresectable locally advanced non-small cell lung cancer without chemotherapy met its primary endpoint with tolerable adverse reactions.

8 Aug 2022

Consolidation PD-(L)1 inhibition following concurrent chemoradiation for unresectable stage III NSCLC improves survival

Following concurrent chemoradiation for unresectable stage III non-small cell lung cancer, both nivolumab alone and nivolumab and ipilimumab combined demonstrated improved 18- month progression-free survival compared with historical controls despite a shortened interval (6 months) of treatment.

8 Aug 2022

Lung cancer patients in a screening program who participated in stop smoking study achieve more than 30% abstinence rates

Patients with lung cancer who attended a lung cancer screening event and who then participated in a personalized smoking cessation study achieved smoking abstinence rates of more than 30 percent, according to research presented today at the IASLC World Conference on Lung Cancer 2022 in Vienna.

8 Aug 2022

Neoadjuvant chemoimmunotherapy highly effective in patients with resectable stage IIIA NSCLC

In the initial NADIM trial, neoadjuvant chemoimmunotherapy was shown to be highly effective in patients with resectable stage IIIA non-small cell lung cancer.

8 Aug 2022

Researchers identify immune expression signature in surgical specimens linked to disease progression for non-CPR patients

Researchers from Spain have identified an immune expression signature in surgical specimens associated with disease progression for non-complete pathological responders patients treated with neo adjuvant chemo-immunotherapy, which could help the follow-up and therapeutic management of these high-risk patients.

8 Aug 2022

Trial evaluates sugemalimab as a consolidation treatment in patients with unresectable stage III NSCLC

The human monoclonal antibody sugemalimab is a safe and effective consolidation therapy for patients with unresectable stage III non-small cell lung cancer without disease progression after either concurrent chemoradiotherapy (cCRT) or sequential chemoradiotherapy (sCRT), according to findings presented today at the IASLC World Conference on Lung Cancer 2022 in Vienna.

8 Aug 2022

Study reveals the intertumoral heterogeneity of METex14 skipping positive NSCLCs

A study presented today at the IASLC World Conference on Lung Cancer 2022 in Vienna disclosed the clinical-relevant intertumoral heterogeneity of non-small cell lung cancer (NSCLC) driven by MET exon 14 skipping.

8 Aug 2022

Study compares the nodule management protocols used in NELSON and National Lung Cancer Screening Trial

The protocol used to screen and detect lung cancer in the NELSON Trial is more sensitive than the protocol used in the National Lung Cancer Screening Trial, particularly for early-stage cancers, according to research reported today at the IASLC World Conference on Lung Cancer 2022 in Vienna.

8 Aug 2022

Research highlights the need to increase early detection of lung cancer among younger patients

Younger patients with lung cancer are significantly more likely than older patients to be diagnosed with later stages of disease, illustrating the need to develop strategies to increase the early detection of lung cancer among younger patients who are currently ineligible for lung cancer screening.

8 Aug 2022

Sub lobar surgery found to be non-inferior to lobectomy for patients with small-sized peripheral NSCLC

A large international study of patients with non-small cell lung cancer tumors that are two centimeters or less found that sub lobar surgery was non-inferior to lobectomy, according to results presented today at the IASLC World Conference on Lung Cancer 2022 in Vienna.

8 Aug 2022

Increased use of stereotactic body radiation therapy for NSCLC patients can reduce treatment disparities

The use of Stereotactic Body Radiotherapy (SBRT) for patients with non-small cell lung cancer can reduce treatment disparities between White and Black patients, according to research presented today at the IASLC World Conference on Lung Cancer 2022 in Vienna.

8 Aug 2022

Study demonstrates the success rate of gene analysis using cytological specimens to be extremely high

Personalized medicine for lung cancer using molecular-targeted drugs is common but there have been no prospective validation studies done on the usefulness of lung cancer gene panel testing using cytology samples.

8 Aug 2022

Researchers examine the incidence of second primary lung cancers using National Lung Screening Trial data

Using data from the National Lung Screening Trial, researchers found that the incidence of second primary lung cancer was approximately 4% among the entire cohort of lung cancer patients and was as high as 8% among patients undergoing surgery for stage IA disease.

8 Aug 2022

Biological sex differences may be the reason behind higher cancer risk among men than women

Rates of most types of cancer are higher in men than in women for reasons that are unclear. Results from a recent study published by Wiley online in CANCER, a peer-reviewed journal of the American Cancer Society, suggest that the cause may be underlying biological sex differences rather than behavioral differences related to smoking, alcohol use, diet, and other factors.

8 Aug 2022

Scientists find key molecular differences between breast cancer cells in initial and metastatic tumors

Studying a deadly type of breast cancer called triple negative, Johns Hopkins Medicine scientists say they have identified key molecular differences between cancer cells that cling to an initial tumor and those that venture off to form distant tumors.

8 Aug 2022

Research progress on the three-dimensional interaction between virus and host genome

A recent study reviewed the current progress on 3D interactions between host and viral genomes.

8 Aug 2022

Tribe embraces recreational marijuana sales on reservation where alcohol is banned

In a growing number of U.S. states, people can both drink alcohol and legally smoke recreational marijuana. In others, they can use alcohol but not pot. But on the Pine Ridge Indian Reservation in South Dakota, the opposite is true: Marijuana is legal, but booze is banned.

8 Aug 2022

Implantable mechanotherapeutic drug delivery platform helps overcome host immune response

Implantable devices that release insulin into the body hold promise as an alternative way to treat diabetes without insulin injections or cannula insertions. However, one obstacle that has prevented their use so far is that the immune system attacks them after implantation, forming a thick layer of scar tissue that blocks insulin release.

8 Aug 2022

Terminally exhausted T cells may remain competent for transcription, researchers say

During a battle with cancer, T cells can become exhausted and are no longer able to function properly. The early phase of exhaustion can sometimes be reversed with immunotherapy drugs, but once T cells become too exhausted, it had been thought that this state was irreversible. However, new insights from University of Pittsburgh and UPMC researchers suggest that even the most fatigued T cells can be revived.

8 Aug 2022

Cancer News and Research

Latest Cancer News and Research

Higher doses of CAR-T therapy achieve better survival rates for young patients with hard-to-treat B-ALL

First Phase II study of immunotherapy combined with curative radiotherapy for unresectable locally advanced NSCLC

Consolidation PD-(L)1 inhibition following concurrent chemoradiation for unresectable stage III NSCLC improves survival

Lung cancer patients in a screening program who participated in stop smoking study achieve more than 30% abstinence rates

Neoadjuvant chemoimmunotherapy highly effective in patients with resectable stage IIIA NSCLC

Researchers identify immune expression signature in surgical specimens linked to disease progression for non-CPR patients

Trial evaluates sugemalimab as a consolidation treatment in patients with unresectable stage III NSCLC

Study reveals the intertumoral heterogeneity of METex14 skipping positive NSCLCs

Study compares the nodule management protocols used in NELSON and National Lung Cancer Screening Trial

Research highlights the need to increase early detection of lung cancer among younger patients

Sub lobar surgery found to be non-inferior to lobectomy for patients with small-sized peripheral NSCLC

Increased use of stereotactic body radiation therapy for NSCLC patients can reduce treatment disparities

Study demonstrates the success rate of gene analysis using cytological specimens to be extremely high

Researchers examine the incidence of second primary lung cancers using National Lung Screening Trial data

Biological sex differences may be the reason behind higher cancer risk among men than women

Scientists find key molecular differences between breast cancer cells in initial and metastatic tumors

Research progress on the three-dimensional interaction between virus and host genome

Tribe embraces recreational marijuana sales on reservation where alcohol is banned

Implantable mechanotherapeutic drug delivery platform helps overcome host immune response

Terminally exhausted T cells may remain competent for transcription, researchers say

Understanding the DNA Damage Response in Innate Immunity eBook

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting

Cancer News and Research

Latest Cancer News and Research

Understanding the DNA Damage Response in Innate Immunity eBook

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting

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