Gene News and Research

Latest Gene News and Research

Testing amniotic fluid could guide doctors to make delivery planning decisions for preterm births

Analyzing gene expression of an expectant mother's amniotic fluid could give doctors an important tool for deciding when it is safe to deliver premature babies.

28 Oct 2015

Virginia Tech researchers study how specific cytokine influences gene expression patterns in T helper cells

Environment can make all the difference in behavior - even at the cellular level. Scientists at the Virginia Tech Carilion Research Institute have discovered even a small shift in environmental factors can change how a cell in the immune system matures.

28 Oct 2015

Changes in lifestyle could reduce Alzheimer's disease risk

Changes in lifestyle could reduce the risk of developing Alzheimer's disease. That was the conclusion of a study conducted by researchers of Heidelberg University's Network Aging Research, who examined the data from two independent epidemiological studies. Carriers of the ApoE4 genetic risk factor for Alzheimer's may be able to reduce their increased risk of cognitive decline by reducing their cholesterol level, especially if they also suffer from cardiovascular disease.

27 Oct 2015

Study uncovers new genetic variants linked to increased risk of testicular cancer

A new study of more than 25,000 men has uncovered four new genetic variants associated with increased risk of testicular cancer.

27 Oct 2015

Targeting invasive cells could be a new strategy to treat metastatic cancer, say Stony Brook researchers

Most cancer drugs are designed to target dividing cells, but a new study by Stony Brook University researchers suggests that targeting invasive cells may be a new strategy to treat metastatic cancer.

27 Oct 2015

Discovery may open new doors to understanding how melanoma grows and spreads

Of the hundreds of genes that can be mutated in a single case of melanoma, only a handful may be true "drivers" of cancer. In research that recently appeared in Nature Genetics, a Weizmann Institute of Science team has now revealed one of the drivers of a particularly deadly subset of melanomas that is seeing a rise in new cases.

27 Oct 2015

Four microRNAs appear to play critical roles in controlling cholesterol, triglyceride metabolism

Four tiny segments of RNA appear to play critical roles in controlling cholesterol and triglyceride metabolism. In their report receiving advance online publication in Nature Medicine, a Massachusetts General Hospital-based research team describes finding how these microRNAs could reduce the expression of proteins playing key roles in the generation of beneficial HDL cholesterol, the disposal of artery-clogging LDL cholesterol, control of triglyceride levels and other risk factors of cardiovascular disease.

27 Oct 2015

Researchers develop multiplexed screening approach to study cancer development in mice

In a novel use of the CRISPR/Cas9 system, which can be deployed to switch genes off, researchers from Germany, the UK and Spain have developed a multiplexed screening approach to study and model cancer development in mice. The scientists mutated genes in the adult mouse liver uncovering their cancer-causing roles and determining which combinations of genes cooperate to cause liver cancer.

27 Oct 2015

Researchers pinpoint mechanisms that cause chemoresistance in ovarian cancer patients

Resistance to chemotherapy is a major problem for those suffering from ovarian cancer--a problem that prevents a cure from a disease dubbed the "silent killer." University of Georgia researchers are giving patients new hope with recent findings that help pinpoint the mechanisms causing chemoresistance.

27 Oct 2015

Genetic discovery sheds light on how prostate cancer develops and spreads

A new and important genetic discovery, which sheds light on how prostate cancers develop and spread, has been made by an international research team led by scientists at The University of Nottingham.

27 Oct 2015

New drug combination may be effective against malignant melanoma

A team of Massachusetts General Hospital investigators has discovered a new combination of drugs that may be effective against one of the deadliest cancers, malignant melanoma. The combination - pairing a drug targeted against mutations in the BRAF gene with a second drug that targets another important signaling pathway - was discovered through one of the largest screens of cancer drug combinations conducted to date.

27 Oct 2015

Scalable production of gene therapy vectors: an interview with Frank Ubags

Gene therapy involves introducing genetic material into cells to replace missing or malfunctioning genes or to add a gene to express a beneficial protein in order to treat certain diseases, such as cancer or inherited disorders.

26 Oct 2015

UW researchers develop new model to more accurately predict harmful genetic mutations

Between any two people, there are likely to be at least 10 million differences in the genetic sequence that makes up their DNA.

26 Oct 2015

Researchers develop new method to predict people's biological age

New research has shed light on the molecular changes that occur in our bodies as we age. In the largest study of its kind, an international group of researchers, including experts from the University of Exeter's Medical School, examined expression of genes in blood samples from 15,000 people across the world.

26 Oct 2015

Phage shows strong anti-microbial activity against C. sakazakii bacterium

A phage showed strong anti-microbial activity against a type of food-borne bacterium that often kills infants after infecting them via infant formula. Phages are viruses that infect only bacteria. The research is published Oct. 23 online in Applied and Environmental Microbiology, a journal of the American Society for Microbiology.

24 Oct 2015

Improved results yielded from new ChIP-seq protocol

Chromatrap®, a business unit of Porvair Sciences, has developed a new protocol that further extends the many advantages of its popular Chromatin Immunoprecipitation Sequencing (ChIP-seq) assay kits.

From Chromatrap® - Porvair Sciences Ltd 23 Oct 2015

Spatial grid pattern in brain region is altered in young adults with Alzheimer's risk

Young adults with genetically increased Alzheimer's risk have altered activation patterns in a brain region that is crucial for spatial navigation.

23 Oct 2015

MU researchers successfully treat dogs with DMD, plan for human clinical trials

Muscular dystrophy, which affects approximately 250,000 people in the U.S., occurs when damaged muscle tissue is replaced with fibrous, fatty or bony tissue and loses function. For years, scientists have searched for a way to successfully treat the most common form of the disease, Duchenne Muscular Dystrophy (DMD), which primarily affects boys. Now, a team of University of Missouri researchers have successfully treated dogs with DMD and say that human clinical trials are being planned in the next few years.

23 Oct 2015

Stem cell biology and gene-editing techniques offer hope for kidney regeneration

Mini-kidney organoids have now been grown in a laboratory by using genome editing to re-create human kidney disease in petri dishes.

23 Oct 2015

Patrolling monocytes may play anti-cancer role in the lung

One goal of immunotherapy is to rally a patient's often over-burdened immune cells to effectively attack a tumor. Among foot soldiers on the immune front line is a subpopulation of white blood cells called "patrolling monocytes," whose job is to cruise the bloodstream, cart off cellular debris, and block invasion of a less benign population of inflammatory cells.

23 Oct 2015

Gene News and Research

Latest Gene News and Research

Testing amniotic fluid could guide doctors to make delivery planning decisions for preterm births

Virginia Tech researchers study how specific cytokine influences gene expression patterns in T helper cells

Changes in lifestyle could reduce Alzheimer's disease risk

Study uncovers new genetic variants linked to increased risk of testicular cancer

Targeting invasive cells could be a new strategy to treat metastatic cancer, say Stony Brook researchers

Discovery may open new doors to understanding how melanoma grows and spreads

Four microRNAs appear to play critical roles in controlling cholesterol, triglyceride metabolism

Researchers develop multiplexed screening approach to study cancer development in mice

Researchers pinpoint mechanisms that cause chemoresistance in ovarian cancer patients

Genetic discovery sheds light on how prostate cancer develops and spreads

New drug combination may be effective against malignant melanoma

Scalable production of gene therapy vectors: an interview with Frank Ubags

UW researchers develop new model to more accurately predict harmful genetic mutations

Researchers develop new method to predict people's biological age

Phage shows strong anti-microbial activity against C. sakazakii bacterium

Improved results yielded from new ChIP-seq protocol

Spatial grid pattern in brain region is altered in young adults with Alzheimer's risk

MU researchers successfully treat dogs with DMD, plan for human clinical trials

Stem cell biology and gene-editing techniques offer hope for kidney regeneration

Patrolling monocytes may play anti-cancer role in the lung

eBook: Using iPSCs models for human disease research and drug discovery eBook

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