Gene News and Research

Latest Gene News and Research

Sysmex unveils latest series of haematology analysers at IFCC congress

The Sysmex Corporation, the global leader in haematology, unveiled its latest series of haematology analysers at the annual IFCC congress, EuroMedLab JIB in Paris today. The XN-L series follows in the footsteps of its game-changing big brother, the XN-Series. The new, smaller XN-L Series makes top quality haematology available for all.

From Sysmex America, Inc. 22 Jun 2015

Study opens new area of discovery for different aspects of cell biology, biomedical research

Every cell in the body uses phosphorylation, the process of adding a chemical tag to control a protein's function and fate, such as when it moves from one part of a cell to another or binds to other proteins.

19 Jun 2015

UNC Lineberger scientists contribute to better understanding of genetic mutations in melanoma

UNC Lineberger Comprehensive Cancer Center researchers have significantly contributed to a better understanding of the genetic alterations found in cutaneous melanoma, the most lethal form of skin cancer, as part of a multi-institution, international effort of The Cancer Genome Atlas.

19 Jun 2015

Lilly announces positive results from LY2951742 Phase 2b study in patients with episodic migraine

Eli Lilly and Company announced today that its investigational medicine for prevention of migraine (LY2951742, a CGRP neutralizing antibody) met the primary endpoint in a Phase 2b study in episodic migraine.

19 Jun 2015

WSU research provides new strategies for prevention, treatment of obesity

Washington State University scientists have shown that berries, grapes and other fruits convert excess white fat into calorie-burning "beige" fat, providing new strategies for the prevention and treatment of obesity.

19 Jun 2015

Mayo Clinic, TGen researchers help launch national clinical trial to treat advanced skin cancer patients

Mayo Clinic and the Translational Genomics Research Institute are helping launch a national clinical trial that will apply the latest in precision medicine to treat advanced melanoma skin cancer.

19 Jun 2015

UCSF scientists identify characteristics of progenitor cells

University of California San Francisco scientists have identified characteristics of a family of daughter cells, called MPPs, which are the first to arise from stem cells within bone marrow that generate the entire blood system. The researchers said the discovery raises the possibility that, by manipulating the fates of MPPs or parent stem cells, medical researchers could one day help overcome imbalances and deficiencies that can arise in the blood system due to aging or in patients with specific types of leukemia.

19 Jun 2015

International researchers identify previously unknown genetic immunodeficiency

An analysis of five families has revealed a previously unknown genetic immunodeficiency, says an international team led by researchers from Boston Children's Hospital. The condition, linked to mutations in a gene called DOCK2, deactivates many features of the immune system and leaves affected children open to a unique pattern of aggressive, potentially fatal infections early in life.

19 Jun 2015

University of Delaware researchers identify prime suspects in cataract formation

When cataracts encroach on the eyes, the only effective remedy is to surgically replace the eyes' lenses with synthetic substitutes. But what if scientists found a way to delay or prevent cataracts from forming in the first place? Researchers at the University of Delaware may have found such an opportunity by identifying the prime suspects in the formation of cataracts - deficiency of two genes that encode regulatory proteins.

19 Jun 2015

Researchers explore the science of exosomes in heart repair

A little more than a decade ago, researchers discovered that all cells secrete tiny communications modules jammed with an entire work crew of messages for other cells. Today, a team of researchers, led by stem cell researcher Raj Kishore, PhD, Director of the Stem Cell Therapy Program at the Center for Translational Medicine at Temple University School of Medicine, is harnessing the communications vesicles excreted by stem cells and using them to induce the damaged heart to repair itself.

19 Jun 2015

Nucleoporin proteins play significant role in maintaining embryonic stem cells

What if you found out that pieces of your front door were occasionally flying off the door frame to carry out chores around the house? That's the kind of surprise scientists at the Salk Institute experienced with their recent discovery that nucleoporins -- proteins that act as cellular 'doorways' to help manage what goes in and out of a cell's nucleus -- are actually much bigger players in expressing genes than previously thought.

19 Jun 2015

HUJI professor honored with Helmholtz International Fellow Award for epigenetics research

The Israeli immunologist and cancer researcher Professor Yehudit Bergman of the Hebrew University of Jerusalem, Israel, has been honored with the Helmholtz International Fellow Award for her excellent research. In a prize ceremony at the MDC Max Delbrück Center for Molecular Medicine in the Helmholtz Association in Berlin, Germany, MDC's interim director Professor Thomas Sommer presented the certificate to her on Thursday, June 18th, 2015.

19 Jun 2015

Study demonstrates potential of new approach for sorting out BRCA1 gene variants

Patients seeking certainty in genetic tests often receive a perplexing result. Many learn they carry a 'variant of unknown significance' of a disease-linked gene. Such variants might -- or equally might not -- increase disease risk.

19 Jun 2015

UB study sheds light on the molecular basis of cocaine addiction

Researchers at the University at Buffalo have discovered a previously unknown neural pathway that can regulate changes made in the brain due to cocaine use, providing new insight into the molecular basis of cocaine addiction.

19 Jun 2015

EPFL scientists show how a major effector protein binds chromatin and regulates gene expression

Inside the cell, DNA is tightly coiled and packed with several proteins into a structure called "chromatin", which allows DNA to fit in the cell while also preventing genes from being expressed at the wrong time. Guided by a chemical "barcode", specialized effector proteins can bind chromatin and either unwind it or compact further to activate or silence genes.

18 Jun 2015

Researchers track down key gene mutation responsible for causing acute lymphoblastic leukemia

Two medical researchers from the Children's Hospital of Michigan and the Wayne State University School of Medicine have published the results of a nearly 10-year investigation that identified a key gene mutation that can trigger acute lymphoblastic leukemia, or ALL, and several other types of cancer.

18 Jun 2015

Findings could lead to treatments for chronic pain caused by nerve damage

Non-narcotic treatments for chronic pain that work well in people, not just mice, are sorely needed. Drawing from human pain genetics, an international team led by Boston Children's Hospital demonstrates a way to break the cycle of pain hypersensitivity without the development of addiction, tolerance or side effects.

18 Jun 2015

High fructose consumption can lead to uncontrolled growth of cardiomyocytes, heart attack

'Walk through any supermarket and take a look at the labels on food products, and you'll see that many of them contain fructose, often in the form of sucrose (table sugar)' -- that's how Wilhelm Krek, professor for cell biology at ETH Zurich's Institute for Molecular Health Sciences, summarises the problem with today's nutrition.

18 Jun 2015

NIH-funded study identifies DOCK2 deficiency

Researchers funded by the National Institutes of Health have identified a new immune disorder--DOCK2 deficiency--named after the mutated gene responsible for the disease.

18 Jun 2015

ExCellThera's stem cell expansion approach may benefit AML patients undergoing transplants

Patients suffering from acute myeloid leukemia, who require stem cell transplantation as part of their treatment,may now benefit from a new best-in-class process that improves the viability and success of cord blood stem cell transplantation.

18 Jun 2015

Gene News and Research

Latest Gene News and Research

Sysmex unveils latest series of haematology analysers at IFCC congress

Study opens new area of discovery for different aspects of cell biology, biomedical research

UNC Lineberger scientists contribute to better understanding of genetic mutations in melanoma

Lilly announces positive results from LY2951742 Phase 2b study in patients with episodic migraine

WSU research provides new strategies for prevention, treatment of obesity

Mayo Clinic, TGen researchers help launch national clinical trial to treat advanced skin cancer patients

UCSF scientists identify characteristics of progenitor cells

International researchers identify previously unknown genetic immunodeficiency

University of Delaware researchers identify prime suspects in cataract formation

Researchers explore the science of exosomes in heart repair

Nucleoporin proteins play significant role in maintaining embryonic stem cells

HUJI professor honored with Helmholtz International Fellow Award for epigenetics research

Study demonstrates potential of new approach for sorting out BRCA1 gene variants

UB study sheds light on the molecular basis of cocaine addiction

EPFL scientists show how a major effector protein binds chromatin and regulates gene expression

Researchers track down key gene mutation responsible for causing acute lymphoblastic leukemia

Findings could lead to treatments for chronic pain caused by nerve damage

High fructose consumption can lead to uncontrolled growth of cardiomyocytes, heart attack

NIH-funded study identifies DOCK2 deficiency

ExCellThera's stem cell expansion approach may benefit AML patients undergoing transplants

Industry Focus: Cell & Gene Therapy eBook

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Todd Bauman and Chris Povich