Gene News and Research

Latest Gene News and Research

Scientists reveal how disruption of DISC1 gene involved in mental illness affects the brain

Scientists have for the first time shown how the disruption of a key gene involved in mental illness impacts on the brain.

24 May 2015

Mayo Clinic scientists create mouse model of ALS, FTD caused by mutations in C9ORF72 gene

Scientists at Mayo Clinic, Jacksonville, Florida created a novel mouse that exhibits the symptoms and neurodegeneration associated with the most common genetic forms of frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS, Lou Gehrig's disease), both of which are caused by a mutation in the a gene called C9ORF72.

24 May 2015

Clinical genomic sequencing could impact treatment decisions in advanced prostate cancer patients

An international collaboration of researchers are advancing precision medicine to men with advanced prostate cancer.

22 May 2015

Sex-determining gene in mosquitoes may help reduce disease transmission

Researchers with the Fralin Life Science Institute at Virginia Tech have identified a gene responsible for sex determination in mosquitoes that can transmit yellow fever, dengue, and chikungunya viruses.

22 May 2015

TGen and Baylor partnership set to increase treatment options for cancer patients

The Translational Genomics Research Institute (TGen) and Baylor Research Institute (BRI) at Dallas today announce an agreement that will focus on accelerating early detection and treatments for patients with a broad range of cancers.

22 May 2015

Splicing pattern of obesity, type 2 diabetes genes may contribute to pathophysiology of obesity

Alternative splicing of obesity and type 2 diabetes related genes may contribute to the pathophysiology of obesity, according to research from the University of Eastern Finland. Obesity leads to changes in the splicing pattern of metabolically relevant genes such as TCF7L2 and INSR, resulting in impaired insulin action.

22 May 2015

Certain proteins may slow cognitive decline in people with Alzheimer's disease

Certain proteins may slow the devastating memory loss caused by Alzheimer's disease, according to a groundbreaking Iowa State University study.

21 May 2015

Nanoparticle-based therapy effective in treating mice with multiple myeloma

Researchers have designed a nanoparticle-based therapy that is effective in treating mice with multiple myeloma, a cancer of immune cells in the bone marrow.

21 May 2015

Untangling the Web of Gene Expression

With enhancers and other regulatory elements often lying 10s to 100s of kilobases from the genes they affect, understanding the regulation of gene expression is an incredibly complex endeavor...

From Integrated DNA Technologies 21 May 2015

Non-coding micro RNA molecule may control chemotherapy resistance among ovarian cancer patients

A molecule that helps control gene expression may play a role in controlling chemotherapy resistance among patients with the most common form of ovarian cancer.

21 May 2015

First-of-its-kind DNA bank aims at advancing research into genetics of stuttering

Scientists at the University of Alberta's Institute for Stuttering Treatment and Research want Albertans to give a spit -- five millilitres to be precise -- to help find the cause and a cure for stuttering.

21 May 2015

Scientists reveal how lymphatic system develops in embryo

For over one hundred years, scientists have debated the question of the origins of the lymphatic system - a parallel system to the blood vessels that serves as a conduit for everything from immune cells to fat molecules to cancer cells. This issue has now been resolved by Dr. Karina Yaniv of Weizmann Institute's Biological Regulation Department. In a study reported online today in Nature, she and her team revealed how the lymphatic system develops in the embryo and for the first time managed to grow lymphatic cells in the lab.

21 May 2015

Kidney function plays critical role in sepsis patients

Researchers at Duke Medicine have determined that kidney function plays a critical role in the fate of patients being treated for sepsis, a potentially life-threatening complication of an infection.

21 May 2015

Research may offer new targets for diagnosing, treating advanced prostate cancer

Researchers with the Indiana University School of Medicine have identified a molecule that promotes metastasis of advanced prostate cancer to the bone, an incurable condition that significantly decreases quality of life.

20 May 2015

IDT facilitates versatile, scalable solution to enrich enhancer:promoter interactions

Advancing the development of novel methods for understanding gene expression, Integrated DNA Technologies has enabled Dr Jim Hughes, Associate Professor at the Weatherall Institute of Molecular Medicine, Oxford, UK, to optimize his unique Capture-C method, based on Chromosomal Conformational Capture (3C).

From Integrated DNA Technologies 20 May 2015

New study suggests ways to accelerate recovery from dangerous diarrheal disease

A new study delineates a sequential pattern of changes in the intestinal microbial population of patients recovering from cholera in Bangladesh, findings that may point to ways of speeding recovery from the dangerous diarrheal disease.

20 May 2015

Omega-3 fatty acids improve cognitive flexibility in older adults at risk of late-onset Alzheimer's disease

A study of older adults at risk of late-onset Alzheimer's disease found that those who consumed more omega-3 fatty acids did better than their peers on tests of cognitive flexibility -- the ability to efficiently switch between tasks -- and had a bigger anterior cingulate cortex, a brain region known to contribute to cognitive flexibility.

20 May 2015

Johns Hopkins researchers identify new therapy to treat lung cancer

A multidisciplinary team led by Johns Hopkins researcher Venu Raman, Ph.D., with notable contributions from Guus Bol, Farhad Vesuna and Phuoc Tran of Johns Hopkins, has identified a new therapy for lung cancer, the most common cancer worldwide. The therapy has been in development for six years and involves a first-in-class molecule designed by the team.

20 May 2015

Corus CAD test can help clinicians rule-out low-risk patients from additional cardiac testing

CardioDx, Inc., a molecular diagnostics company specializing in cardiovascular genomics, announced today results from a multi-center, community-based patient registry, the PRESET Registry, evaluating the use of the Corus CAD test in patients with symptoms suggestive of obstructive coronary artery disease (CAD) in the primary care setting.

20 May 2015

New research points to potential therapeutic target for treating multiple sclerosis

New research into the causes of the excessive inflammation that drives multiple sclerosis has identified a faulty "brake" within immune cells, a brake that should be controlling the inflammation. This points to a potential target for developing new therapies to treat multiple sclerosis and could have important implications for other autoimmune diseases, such as the colon disease colitis and the chronic skin condition atopic dermatitis.

20 May 2015

Gene News and Research

Latest Gene News and Research

Scientists reveal how disruption of DISC1 gene involved in mental illness affects the brain

Mayo Clinic scientists create mouse model of ALS, FTD caused by mutations in C9ORF72 gene

Clinical genomic sequencing could impact treatment decisions in advanced prostate cancer patients

Sex-determining gene in mosquitoes may help reduce disease transmission

TGen and Baylor partnership set to increase treatment options for cancer patients

Splicing pattern of obesity, type 2 diabetes genes may contribute to pathophysiology of obesity

Certain proteins may slow cognitive decline in people with Alzheimer's disease

Nanoparticle-based therapy effective in treating mice with multiple myeloma

Untangling the Web of Gene Expression

Non-coding micro RNA molecule may control chemotherapy resistance among ovarian cancer patients

First-of-its-kind DNA bank aims at advancing research into genetics of stuttering

Scientists reveal how lymphatic system develops in embryo

Kidney function plays critical role in sepsis patients

Research may offer new targets for diagnosing, treating advanced prostate cancer

IDT facilitates versatile, scalable solution to enrich enhancer:promoter interactions

New study suggests ways to accelerate recovery from dangerous diarrheal disease

Omega-3 fatty acids improve cognitive flexibility in older adults at risk of late-onset Alzheimer's disease

Johns Hopkins researchers identify new therapy to treat lung cancer

Corus CAD test can help clinicians rule-out low-risk patients from additional cardiac testing

New research points to potential therapeutic target for treating multiple sclerosis

Industry Focus: Cell & Gene Therapy eBook

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