Gene News and Research

Latest Gene News and Research

Gene therapy is key to addressing Sanfilippo Syndrome, say Ohio scientists and clinicians

Gene therapy is the delivery of DNA into a patient's cells to replace faulty or missing genes—or adds new genes—in an attempt to cure cancer or make changes so the body is better able to fight off disease. Scientists and clinicians have identified a number of different ways to do this, in an effort to correct malfunctioning or mutated genes. Many gene therapy clinical trials are ongoing to assess the safety and potential benefits in patients with rare diseases.

8 May 2015

GTEx findings reveal how genomic variants can affect gene activity and disease susceptibility

Researchers funded by the National Institutes of Health Genotype-Tissue Expression (GTEx) project have created a new and much-anticipated data resource to help establish how differences in an individual's genomic make-up can affect gene activity and contribute to disease.

8 May 2015

Discovery may have opened up new frontier in fight against breast cancer

For years, scientists have been puzzled by the presence of short stretches of genetic material floating inside a variety of cells, ranging from bacteria to mammals, including humans. These fragments are pieces of the genetic instructions cells use to make proteins, but are too short a length to serve their usual purpose.

8 May 2015

Noninvasive nuclear medicine test can help determine effectiveness of aromatase inhibitor treatment

A new, noninvasive nuclear medicine test can be used to determine whether aromatase inhibitor treatment will be effective for specific cancer patients, according to a recent study reported in The Journal of Nuclear Medicine.

8 May 2015

Myriad to present new clinical data on Prolaris® at the AUA 2015 annual meeting

Myriad Genetics, Inc. announced it will present three studies that demonstrate the value of the Prolaris test for physicians and their patients at the 2015 American Urological Association (AUA) Annual Meeting being held May 15 to 19 in New Orleans, La...

7 May 2015

Quest Diagnostics launches genomic test service that aids in diagnosis for myeloid neoplasms

Quest Diagnostics, the world's leading provider of diagnostic information services, today announced LeukoVantage, an evidence-based genomic test service that aids in the diagnosis, prognosis, monitoring and selection of treatment for myeloid neoplasms, a group of hematologic malignancies that includes acute myeloid leukemia (AML), the most common form of adult acute leukemia, as well as myelodysplastic syndrome (MDS) and myeloproliferative neoplasms (MPNs).

From Quest Diagnostics 7 May 2015

Positive data from two studies analyzing Good Start's test for inherited diseases presented at ACOG 2015

Good Start Genetics, Inc., a commercial-stage molecular genetics information company, today presented data from two studies analyzing detection rates among patients at in vitro fertilization (IVF) clinics who underwent carrier screening for inherited diseases. The studies were presented at the 2015 Annual Clinical and Scientific Meeting of The American College of Obstetricians and Gynecologists being held in San Francisco, Calif.

7 May 2015

Cardiff scientists develop novel anti-cancer stem cell compound

Cardiff University scientists have developed a novel anti-cancer stem cell agent capable of targeting aggressive tumour forming cells common to breast, pancreas, colon and prostate cancers.

7 May 2015

Salk discovery may offer new avenues for generating novel therapies

Scientists at the Salk Institute have discovered a novel type of pluripotent stem cell--cells capable of developing into any type of tissue--whose identity is tied to their location in a developing embryo. This contrasts with stem cells traditionally used in scientific study, which are characterized by their time-related stage of development.

7 May 2015

EKF introduces specific biomarker test for early sepsis identification

EKF Diagnostics, the global diagnostics company, announces that it has introduced the Stanbio Chemistry Procalcitonin (PCT) LiquiColor® Assay.

From EKF Diagnostics 7 May 2015

Researchers compile new genomic interactions catalogue

New clues about diseases like inflammatory bowel disorder may be found thanks to a new genomic interactions catalogue by a group of researchers in Japan and the United Kingdom. This research will be published on May 4, 2015 in Nature Genetics.

6 May 2015

NEB announces issuance of US patent for RNA-seq technology

New England Biolabs, Inc. announces the issuance of United States Patent Number 8,999,677, which describes a novel method for retaining valuable strand-specific information contained within RNA transcripts.

From New England Biolabs 6 May 2015

Zetz Family PCRF, Johns Hopkins Medicine partner for pancreatic cancer research

According to a study done by the Pancreatic Cancer Action Network and published by the Cancer Research Journal, early detection for Pancreatic Cancer is particularly important because it is known as the "silent killer", by the time symptoms appear it is usually too late and is known to have a very low survival rate of 7% over 5 years.

6 May 2015

Relaxation response has significant impact on patients with gastrointestinal disorders

A pilot study has found that participating in a nine-week training program including elicitation of the relaxation response had a significant impact on clinical symptoms of the gastrointestinal disorders irritable bowel syndrome and inflammatory bowel disease and on the expression of genes related to inflammation and the body's response to stress.

6 May 2015

Researchers study early response of cells to ischemia

A group of researchers from the Lomonosov Moscow State University in collaboration with their Irish colleagues from the University College Cork has studied the early response of cells to ischemia, which is a restriction in blood supply to tissues causing the death of the cell.

6 May 2015

Researchers identify gene variant that affects onset of Huntington's disease

Researchers at Sweden's Karolinska Institutet and the University of British Columbia, Canada, have identified a gene variant that influences whether Huntington's disease breaks out earlier or later than expected. The findings, which are published in the scientific journal Nature Neuroscience, can contribute to improved diagnosis and disease-modifying therapies.

5 May 2015

CMC Biologics to supply bulk drug substance for Emergent BioSolutions' IXINITY

CMC Biologics, Inc., a global CMO dedicated to process development and production of biopharmaceuticals for clinical and commercial use, today announced that it will supply bulk drug substance for Emergent BioSolutions' recently FDA-approved product, IXINITY® [coagulation factor IX (recombinant)].

5 May 2015

Researchers identify mechanism responsible for steroid resistance in leukemia patients

Researchers led by St. Jude Children's Research Hospital scientists have identified a mechanism that helps leukemia cells resist glucocorticoids, a finding that lays the foundation for more effective treatment of cancer and possibly a host of autoimmune diseases.

5 May 2015

New understanding of how Huntington's disease gene works

Huntington's disease is caused by a mutation in the Huntington's disease gene, but it has long been a mystery why some people with the exact same mutation get the disease more severely and earlier than others. A closer look at the DNA around the Huntington's disease (HD) gene offers researchers a new understanding of how the gene is controlled and how this affects the disease.

5 May 2015

Findings provide glimmer of hope for treating diffuse intrinsic pontine gliomas

Using brain tumor samples collected from children in the United States and Europe, an international team of scientists found that the drug panobinostat and similar gene regulating drugs may be effective at treating diffuse intrinsic pontine gliomas (DIPG), an aggressive and lethal form of pediatric cancer.

5 May 2015

Gene News and Research

Latest Gene News and Research

Gene therapy is key to addressing Sanfilippo Syndrome, say Ohio scientists and clinicians

GTEx findings reveal how genomic variants can affect gene activity and disease susceptibility

Discovery may have opened up new frontier in fight against breast cancer

Noninvasive nuclear medicine test can help determine effectiveness of aromatase inhibitor treatment

Myriad to present new clinical data on Prolaris® at the AUA 2015 annual meeting

Quest Diagnostics launches genomic test service that aids in diagnosis for myeloid neoplasms

Positive data from two studies analyzing Good Start's test for inherited diseases presented at ACOG 2015

Cardiff scientists develop novel anti-cancer stem cell compound

Salk discovery may offer new avenues for generating novel therapies

EKF introduces specific biomarker test for early sepsis identification

Researchers compile new genomic interactions catalogue

NEB announces issuance of US patent for RNA-seq technology

Zetz Family PCRF, Johns Hopkins Medicine partner for pancreatic cancer research

Relaxation response has significant impact on patients with gastrointestinal disorders

Researchers study early response of cells to ischemia

Researchers identify gene variant that affects onset of Huntington's disease

CMC Biologics to supply bulk drug substance for Emergent BioSolutions' IXINITY

Researchers identify mechanism responsible for steroid resistance in leukemia patients

New understanding of how Huntington's disease gene works

Findings provide glimmer of hope for treating diffuse intrinsic pontine gliomas

eBook: Using iPSCs models for human disease research and drug discovery eBook

How the Vutara VXL simplifies single-molecule imaging

How cohesin mechanics and nanotracker tech are redefining DNA research

Todd Bauman and Chris Povich