Gene News and Research

Latest Gene News and Research

Researchers uncover role of epigenetic changes in Alzheimer's disease

A team led by researchers at the University of Exeter Medical School and King's College London has uncovered some of the strongest evidence yet that epigenetic changes in the brain play a role in Alzheimer's disease.

19 Aug 2014

BGRF scientists propose Oncofinder method for accurate analysis of gene expression data

Scientists from the Biogerontology Research Foundation (BGRF), a UK-based charity founded to support ageing research and address the challenges of a rapidly ageing population, propose a new concept for signalome-wide analysis of changes in intracellular pathways, called OncoFinder, which allows for accurate and robust cross-platform analysis of gene expression data.

19 Aug 2014

Research findings call for clinical testing of relevant drugs to prevent NASH

Non-alcoholic fatty liver disease (NAFLD) is a common affliction, affecting almost 30 percent of Americans, with a significant number suffering from its most severe form, called non-alcoholic steatohepatitis or NASH, which can lead to cirrhosis and liver cancer. In recent years, NASH has become the leading cause of liver transplantation.

19 Aug 2014

Targeting club cells may help shorten duration of flu symptoms

A specialized subset of lung cells can shake flu infection, yet they remain stamped with an inflammatory gene signature that wreaks havoc in the lung, according to a study published in The Journal of Experimental Medicine.

19 Aug 2014

BRCA2 mutations herald poor prognosis in screen-detected prostate cancer

Among men with prostate cancer detected on screening, survival among those with a mutation in the BRCA2 gene is much poorer than in those without such a mutation, researchers report.

18 Aug 2014

Rare mutation in suspect gene disrupts brain circuitry in complex psychiatric disorders

Researchers have long suspected that major mental disorders are genetically-rooted diseases of synapses - the connections between neurons.

18 Aug 2014

Individual’s genetic make-up determines effect of stress on emotional centres

Our individual genetic make-up determines the effect that stress has on our emotional centres. These are the findings of a group of researchers from the MedUni Vienna. Not every individual reacts in the same way to life events that produce the same degree of stress.

18 Aug 2014

Study identifies genetic basis for Tibetan adaptation

In an environment where others struggle to survive, Tibetans thrive in the thin air on the Tibetan Plateau, with an average elevation of 14,800 feet.

18 Aug 2014

Researchers use new gene editing method to correct mutation that leads to DMD

UT Southwestern Medical Center researchers successfully used a new gene editing method to correct the mutation that leads to Duchenne muscular dystrophy (DMD) in a mouse model of the condition.

17 Aug 2014

Scientists create computer algorithm for cell and tissue engineering

In a boon to stem cell research and regenerative medicine, scientists at Boston Children's Hospital, the Wyss Institute for Biologically Inspired Engineering at Harvard University and Boston University have created a computer algorithm called CellNet as a "roadmap" for cell and tissue engineering, to ensure that cells engineered in the lab have the same favorable properties as cells in our own bodies.

16 Aug 2014

Hippo pathway identifies and prevents progression of abnormal cells into cancer

Researchers from Boston University School of Medicine report that a tumor suppressor pathway, called the Hippo pathway, is responsible for sensing abnormal chromosome numbers in cells and triggering cell cycle arrest, thus preventing progression into cancer.

16 Aug 2014

Illness-linked genetic variation affects connections among neurons in the developing brain

A genetic variation linked to schizophrenia, bipolar disorder and severe depression wreaks havoc on connections among neurons in the developing brain, a team of researchers reports.

16 Aug 2014

New x-ray imaging system helps monitor effectiveness of treatment for cystic fibrosis

Scientists have developed an x-ray imaging system that enables researchers to see 'live' how effective treatments are for cystic fibrosis.

16 Aug 2014

Enzyme therapy may prevent skeletal abnormalities associated with neurofibromatosis type-1

An enzyme therapy may prevent skeletal abnormalities associated with the genetic disorder neurofibromatosis type-1, Vanderbilt investigators have discovered.

15 Aug 2014

Research offers promise for personalized RNA combination therapies to treat lung cancer

Small RNA molecules, including microRNAs (miRNAs) and small interfering RNAs (siRNAs), offer tremendous potential for new therapeutic agents to inhibit cancer cell growth. However, delivering these small RNAs to solid tumors remains a significant challenge, as the RNAs must target the correct cells and avoid being broken down by enzymes in the body.

15 Aug 2014

New therapeutic strategy to combat common genetic risk factor for ALS, FTD

A team of researchers at Mayo Clinic and The Scripps Research Institute in Florida have developed a new therapeutic strategy to combat the most common genetic risk factor for the neurodegenerative disorders amyotrophic lateral sclerosis (ALS or Lou Gehrig's disease) and frontotemporal dementia (FTD).

15 Aug 2014

NTU research could lead to better treatment options for children suffering from leukaemia

A research team led by Nanyang Technological University scientists have made a key finding which is expected to open up improved treatment possibilities for children suffering from leukaemia.

15 Aug 2014

HDAC inhibitors may also be effective against kidney stones

Anyone who has suffered from kidney stones is keenly aware of the lack of drugs to treat the condition, which often causes excruciating pain.

15 Aug 2014

Researchers find method to repair gene mutation causing autoimmune deficiency disease

Researchers at Karolinska Institutet in Sweden have found a method to repair the gene mutation causing agammaglobulinemia, an autoimmune deficiency disease that almost exclusively affects boys and in which the body lacks the ability to produce immunoglobulins (gamma globulin).

14 Aug 2014

Researchers find that nanopores in material MoS2 could sequence DNA more accurately

Gene-based personalized medicine has many possibilities for diagnosis and targeted therapy, but one big bottleneck: the expensive and time-consuming DNA-sequencing process.

14 Aug 2014

Gene News and Research

Latest Gene News and Research

Researchers uncover role of epigenetic changes in Alzheimer's disease

BGRF scientists propose Oncofinder method for accurate analysis of gene expression data

Research findings call for clinical testing of relevant drugs to prevent NASH

Targeting club cells may help shorten duration of flu symptoms

BRCA2 mutations herald poor prognosis in screen-detected prostate cancer

Rare mutation in suspect gene disrupts brain circuitry in complex psychiatric disorders

Individual’s genetic make-up determines effect of stress on emotional centres

Study identifies genetic basis for Tibetan adaptation

Researchers use new gene editing method to correct mutation that leads to DMD

Scientists create computer algorithm for cell and tissue engineering

Hippo pathway identifies and prevents progression of abnormal cells into cancer

Illness-linked genetic variation affects connections among neurons in the developing brain

New x-ray imaging system helps monitor effectiveness of treatment for cystic fibrosis

Enzyme therapy may prevent skeletal abnormalities associated with neurofibromatosis type-1

Research offers promise for personalized RNA combination therapies to treat lung cancer

New therapeutic strategy to combat common genetic risk factor for ALS, FTD

NTU research could lead to better treatment options for children suffering from leukaemia

HDAC inhibitors may also be effective against kidney stones

Researchers find method to repair gene mutation causing autoimmune deficiency disease

Researchers find that nanopores in material MoS2 could sequence DNA more accurately

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