Gene News and Research

Latest Gene News and Research

Differences in brain expression of RORA protein levels may lead to sex bias in autism

George Washington University researcher Valerie Hu, Ph.D., has found an important sex-dependent difference in the level of RORA protein in brain tissues of males and females. Specifically, females without autism have a slightly higher level of RORA in the frontal cortex of the brain than males without autism, while the levels of the protein are comparably lower in the brain of both males and females with autism.

29 May 2015

Sanford-Burnham, Takeda partner to develop new therapeutic targets for cardiovascular disease

Sanford-Burnham Medical Research Institute at Lake Nona today announced it has signed a two-year partnership agreement with Takeda Pharmaceutical Company Ltd. of Japan to study the potential role of several gene regulatory proteins as targets for the treatment of heart failure.

29 May 2015

UB researchers identify mechanisms behind some autistic behaviors, suggest potential targets

Scientists at the University at Buffalo have identified the mechanisms behind a genetic mutation that produces certain autistic behaviors in mice, as well as therapeutic strategies to restore normal behaviors.

28 May 2015

Researchers suggest new target for treating BRAF inhibitor-resistant melanoma tumors

A new collaborative study led by researchers at Sanford-Burnham Medical Research Institute, published today in Cell Reports, provides new insight into the molecular changes that lead to resistance to a commonly prescribed group of drugs called BRAF inhibitors.

28 May 2015

IDT to host instructive talk on accelerating synthetic biology at ASM General Meeting

Integrated DNA Technologies will host an instructive talk on accelerating synthetic biology at the American Society for Microbiology General Meeting in New Orleans, Louisiana on Sunday May 31, 2015 at 11am CDT.

From Integrated DNA Technologies 28 May 2015

EKF Diagnostics highlighting cancer molecular diagnostics products at ASCO 2015

EKF subsidiary, Selah Genomics’ newly introduced PrecisionPath™ next generation sequencing (NGS) technology cancer test will be a key focus on Booth #19141...

From EKF Diagnostics 28 May 2015

College of American Pathologists recognized with ATD's Excellence in Practice Award

The College of American Pathologists was recognized by the Association for Talent Development, formerly ASTD, with an Excellence in Practice Award for its Laboratory Medical Director (LMD) Advanced Practical Pathology Program (AP3) in the Organizational Learning and Development category.

28 May 2015

Research findings could help guide development of potential treatments for HCV

Warring armies use a variety of tactics as they struggle to gain the upper hand. Among their tricks is to attack with a decoy force that occupies the defenders while an unseen force launches a separate attack that the defenders fail to notice.

28 May 2015

Congress needs to act to incentivize development of genomic data systems

The latest generation of genomic testing offers a chance for significant improvements in patient care, disease prevention, and possibly even the cost-effectiveness of healthcare, but Congress needs to act to incentivize the development of the massive data systems that doctors and regulators will need in order to make these tests safe and effective for patients.

28 May 2015

Progression of different types of breast cancer influenced differently by tumor microenvironment

Our environment can have a major impact on how we develop, and it turns out it's no different for cancer cells. In work published today in Neoplasia, a team of researchers led by Associate Professor Mikala Egeblad at Cold Spring Harbor Laboratory found that two different mouse models of breast cancer progressed differently based on characteristics of the tumor microenvironment - the area of tissue in which the tumor is embedded.

28 May 2015

Brigatinib drug shows promise against ALK+ non-small cell lung cancer in phase I/II clinical trial

Phase I/II clinical trial results reported at the American Society for Clinical Oncology (ASCO) Annual Meeting 2015 show promising results for investigational drug brigatinib against ALK+ non-small cell lung cancer (NSCLC), with 58 of 78 ALK+ patients responding to treatment, including 50 of 70 patients who had progressed after previous treatment with crizotinib, the first licensed ALK inhibitor.

28 May 2015

Airway and systemic inflammation predict COPD exacerbation

Researchers have found a link between increased airway and systemic inflammation and frequent exacerbations in patients with chronic obstructive pulmonary disease.

27 May 2015

Researchers use animal models to study how dysfunction of genes contributes to ASD risk

Autism Spectrum Disorder (ASD) is a neurological condition that affects approximately two percent of people around the world. Although several genes have been linked to multiple concurring conditions of ASD, the process that explains how specific genetic variants lead to behaviors characteristic of the disorder remains elusive.

27 May 2015

Strand Life Sciences to launch expanded StrandAdvantage pan-cancer genomic profiling service at ASCO 2015

Strand Life Sciences, a global genomic profiling company that uses next generation sequencing technology to empower cancer care, today announced it will introduce its expanded StrandAdvantage pan-cancer genomic profiling service later this month at the 2015 American Society of Clinical Oncology Annual Meeting in Chicago.

27 May 2015

Six research teams awarded grant to accelerate discovery of new drugs for brain, nervous system disorders

CQDM, Brain Canada and the Ontario Brain Institute award close to $8.5M to six (6) multi-disciplinary and multi-provincial research teams across Canada to address unmet needs in neuroscience within their Focus on Brain strategic initiative. To this amount, $1.5M is added from the various research entities involved as in-kind contributions.

27 May 2015

Ceres receives U.S. patent for genetic sequence obtained from soybean

Ceres, Inc., an agricultural biotechnology company, has been awarded a U.S. patent for a genetic sequence derived from soybean, covering uses of the gene in areas such as research, product development and plant transformation.

27 May 2015

Not feeling pain due to genetic mutation may not be a blessing

A rare congenital genetic mutation means that those affected do not feel pain. However, what seems, at first sight, to be a blessing, can have serious consequences. It means that injuries or diseases can go undetected for a long time. The affected gene was identified by an international research team from MedUni Vienna, the University of Munich and the University of Cambridge.

27 May 2015

Researchers present new program to evaluate clinical relevance of genetic variants

Millions of genetic variants have been discovered over the last 25 years, but interpreting the clinical impact of the differences in a person's genome remains a major bottleneck in genomic medicine. In a paper published in The New England Journal of Medicine on May 27, a consortium including investigators from Brigham and Women's Hospital and Partners HealthCare present ClinGen, a program to evaluate the clinical relevance of genetic variants for use in precision medicine and research.

27 May 2015

UC San Diego Health System designated as Center of Excellence for Huntington's disease

The Huntington's Disease Clinical Research Center at UC San Diego Health System has been designated a Center of Excellence by the Huntington's Disease Society of America. UC San Diego was one of only 29 centers nationwide to receive this prestigious designation, which recognizes centers for their elite multidisciplinary approach to Huntington's disease care and research.

27 May 2015

Scientists identify molecular 'lock' that enables Ebola virus to gain entry to cells

An international team including scientists from Albert Einstein College of Medicine of Yeshiva University and the U.S. Army Medical Research Institute of Infectious Diseases has identified the molecular "lock" that the deadly Ebola virus must pick to gain entry to cells.

27 May 2015

Gene News and Research

Latest Gene News and Research

Differences in brain expression of RORA protein levels may lead to sex bias in autism

Sanford-Burnham, Takeda partner to develop new therapeutic targets for cardiovascular disease

UB researchers identify mechanisms behind some autistic behaviors, suggest potential targets

Researchers suggest new target for treating BRAF inhibitor-resistant melanoma tumors

IDT to host instructive talk on accelerating synthetic biology at ASM General Meeting

EKF Diagnostics highlighting cancer molecular diagnostics products at ASCO 2015

College of American Pathologists recognized with ATD's Excellence in Practice Award

Research findings could help guide development of potential treatments for HCV

Congress needs to act to incentivize development of genomic data systems

Progression of different types of breast cancer influenced differently by tumor microenvironment

Brigatinib drug shows promise against ALK+ non-small cell lung cancer in phase I/II clinical trial

Airway and systemic inflammation predict COPD exacerbation

Researchers use animal models to study how dysfunction of genes contributes to ASD risk

Strand Life Sciences to launch expanded StrandAdvantage pan-cancer genomic profiling service at ASCO 2015

Six research teams awarded grant to accelerate discovery of new drugs for brain, nervous system disorders

Ceres receives U.S. patent for genetic sequence obtained from soybean

Not feeling pain due to genetic mutation may not be a blessing

Researchers present new program to evaluate clinical relevance of genetic variants

UC San Diego Health System designated as Center of Excellence for Huntington's disease

Scientists identify molecular 'lock' that enables Ebola virus to gain entry to cells

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