Gene News and Research

Latest Gene News and Research

Amgen seeks marketing approval of Repatha (evolocumab) in Japan for treatment of high cholesterol

Amgen today announced that an application seeking marketing approval of Repatha (evolocumab) for the treatment of high cholesterol has been submitted for review to the Ministry of Health, Labour and Welfare in Japan.

21 Mar 2015

Eli Lilly, Innovent Biologics announce biotech drug development collaborations in China

Eli Lilly and Company and Innovent Biologics, Inc. today announced one of the largest biotech drug development collaborations in China to date between a multi-national and domestic company.

21 Mar 2015

Shp2 enzyme blocks protection program, boosts tumor growth

Cells have two different programs to safeguard them from getting out of control and developing cancer. One of them is senescence (biological aging). It puts cancer cells into a permanent sleep so they no longer divide and grow in an uncontrolled way.

20 Mar 2015

Cambridge scientists successfully create 'mini-lungs' to study cystic fibrosis

Scientists at the University of Cambridge have successfully created 'mini-lungs' using stem cells derived from skin cells of patients with cystic fibrosis, and have shown that these can be used to test potential new drugs for this debilitating lung disease.

20 Mar 2015

New triple combination therapy shows promise in controlling advanced melanoma

Results of a new study by UCLA researchers has found that a groundbreaking new triple combination therapy shows promising signs of more effectively controlling advanced melanoma than previous BRAF + MEK inhibitor or BRAF inhibitor + immunotherapy combos alone, and with increased immune response and fewer side effects.

20 Mar 2015

RNA molecule can be manipulated to generate more neurons from neural stem cells

A research team at UC San Francisco has discovered an RNA molecule called Pnky that can be manipulated to increase the production of neurons from neural stem cells.

20 Mar 2015

IUPUI professor receives grant to model human motor movements for Huntington's research

Yaroslav Molkov, assistant professor of mathematics in the School of Science at Indiana University-Purdue University Indianapolis, in collaboration with researchers at Drexel University College of Medicine, Philadelphia, has received a grant to use computational modeling to map a motor control system to study Huntington's disease.

20 Mar 2015

PARP inhibitors can be effective in broader group of patients

A pioneering class of drugs that target cancers with mutations in the BRCA breast cancer genes could also work against tumours with another type of genetic fault, a new study suggests.

20 Mar 2015

New technology developed to determine resistance to rabies virus

Researchers at Texas A&M AgriLife Research have developed a new technology to determine sensitivity or resistance to rabies virus.

20 Mar 2015

UF pharmacy dean to be honored with 2015 SURA Distinguished Scientist Award

SURA today announced that Julie A. Johnson, Dean and Distinguished Professor at the University of Florida's College of Pharmacy, will receive its 2015 SURA Distinguished Scientist Award.

20 Mar 2015

Cumulative genetic risk may underlie many Parkinson’s cases

Genetic risk for Parkinson’s disease may be due as much to multiple genes with small individual effects as to single high-risk genes, research suggests.

19 Mar 2015

Study reveals how Grhl2 plays a role in kidney function

The kidney carries out vital functions by continuously filtering the blood and excreting waste products into the urine. This is achieved by a complex system of tubules which transports the urine and regulates its composition.

19 Mar 2015

MTfp-siRNA reduces blood vessel infarct, improves overall brain activity in ischemic stroke model

BIOASIS TECHNOLOGIES INC., a pioneering biopharmaceutical company focused on overcoming the limitations of therapeutic drug delivery across the blood-‐brain barrier (BBB), announces the results from an animal ischemic stroke model performed at the National Research Council Canada with the biOasis Transcend carrier peptide, MTfp and siRNA (MTfp-‐siRNA).

19 Mar 2015

BCM-95 Curcumin improves chemotherapy's effectiveness in killing chemoresistant cancer cells

Cancer cell resistance to chemotherapy is a major cause of death in patients with colorectal cancer. In a first-of-its-kind study, BCM-95 Curcumin was found to improve chemotherapy's effectiveness in killing chemoresistant cells via a mechanism not previously identified.

19 Mar 2015

Scientists identify mystery behind cell-signaling breakdown that causes heart failure

Working with lab animals and human heart cells, scientists from Johns Hopkins and other institutions have identified what they describe as "the long-sought culprit" in the mystery behind a cell-signaling breakdown that triggers heart failure. The condition, which affects nearly 6 million Americans and 23 million people worldwide, is marked by progressive weakening and stiffening of the heart muscle and the organ's gradual loss of blood-pumping ability.

19 Mar 2015

New approach to improve cardiac regeneration

The heart tissue of mammals has limited capacity to regenerate after an injury such as a heart attack, in part due to the inability to reactivate a cardiac muscle cell and proliferation program. Recent studies have indicated a low level of cardiac muscle cell (cardiomyocytes) proliferation in adult mammals, but it is insufficient to repair damaged hearts.

19 Mar 2015

New scoring system may help predict memory and thinking problems in elderly people

Researchers have developed a new scoring system to help determine which elderly people may be at a higher risk of developing the memory and thinking problems that can lead to dementia, according to a new study published in the March 18, 2015, online issue of Neurology, the medical journal of the American Academy of Neurology.

19 Mar 2015

New microarray-based tool provides fast, reliable assessment of vaginal health

A new microarray-based tool, called VaginArray, offers the potential to provide a fast, reliable and low-cost assessment of vaginal health and diagnoses of infections. The research is published ahead of print March 2, in Antimicrobial Agents and Chemotherapy, a journal of the American Society for Microbiology.

19 Mar 2015

New bodily process may explain low blood oxygen levels for cystic fibrosis patients with lung infection

Researchers have defined a new bodily process in mice that may explain why blood oxygen levels are lower for patients with cystic fibrosis when they get a lung infection.

19 Mar 2015

UVA researcher identifies potential therapeutic target for myotonic muscular dystrophy

A doctor who was one of the discoverers of the gene responsible for myotonic muscular dystrophy has now identified a therapeutic that could modify progression of muscle damage and muscle dysfunction associated with the disease - issues that cause patients significant disability and deterioration in quality of life.

19 Mar 2015

Gene News and Research

Latest Gene News and Research

Amgen seeks marketing approval of Repatha (evolocumab) in Japan for treatment of high cholesterol

Eli Lilly, Innovent Biologics announce biotech drug development collaborations in China

Shp2 enzyme blocks protection program, boosts tumor growth

Cambridge scientists successfully create 'mini-lungs' to study cystic fibrosis

New triple combination therapy shows promise in controlling advanced melanoma

RNA molecule can be manipulated to generate more neurons from neural stem cells

IUPUI professor receives grant to model human motor movements for Huntington's research

PARP inhibitors can be effective in broader group of patients

New technology developed to determine resistance to rabies virus

UF pharmacy dean to be honored with 2015 SURA Distinguished Scientist Award

Cumulative genetic risk may underlie many Parkinson’s cases

Study reveals how Grhl2 plays a role in kidney function

MTfp-siRNA reduces blood vessel infarct, improves overall brain activity in ischemic stroke model

BCM-95 Curcumin improves chemotherapy's effectiveness in killing chemoresistant cancer cells

Scientists identify mystery behind cell-signaling breakdown that causes heart failure

New approach to improve cardiac regeneration

New scoring system may help predict memory and thinking problems in elderly people

New microarray-based tool provides fast, reliable assessment of vaginal health

New bodily process may explain low blood oxygen levels for cystic fibrosis patients with lung infection

UVA researcher identifies potential therapeutic target for myotonic muscular dystrophy

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