Gene News and Research

Latest Gene News and Research

Research finding could open new opportunities for treating Huntington's disease

Researchers believe they have learned how mutations in the gene that causes Huntington's disease kill brain cells, a finding that could open new opportunities for treating the fatal disorder. Scientists first linked the gene to the inherited disease more than 20 years ago

24 Jun 2014

Colon has safety mechanism to restrict formation and growth of adenomas

Colon cancer development starts with the formation of benign tumours called adenomas. It is estimated that between 30% and 50% of people over 50 will develop one of these tumours.

24 Jun 2014

Clusters of protein linked to cancer warp cell membranes

Supercomputer simulations have shown that clusters of a protein linked to cancer warp cell membranes, according to scientists at The University of Texas Health Science Center at Houston (UTHealth) Medical School.

24 Jun 2014

Researchers identify two oncogenes that drive the development of medulloblastoma

A new collaborative study carried out by researchers at Sanford-Burnham Medical Research Institute, UC San Diego, the German Cancer Research Center, the University of Heidelberg (Germany), and 33 other research institutions has identified two oncogenes, called GFI1 and GFI1B, that drive the development of medulloblastoma, the most common malignant brain tumor in children.

23 Jun 2014

Investigators discover novel cellular genes by uncovering uncharacterized RNAs that encode proteins

Case Western Reserve School of Medicine scientists have made an extraordinary double discovery. First, they have identified thousands of novel long non-coding ribonucleic acid (lncRNA) transcripts.

23 Jun 2014

Bayer, Dimension Therapeutics partner to develop new gene therapy for hemophilia A

Dimension Therapeutics, a company focused on developing novel adeno-associated virus (AAV) gene therapy treatments for rare diseases, today announced it has entered into a collaboration with Bayer HealthCare (Bayer) for the development and commercialization of a novel gene therapy for the treatment of hemophilia A.

23 Jun 2014

Dimension Therapeutics closes $30M financing to advance novel gene therapy programs

Dimension Therapeutics, a gene therapy company focused on developing novel treatments for rare diseases, today announced the closing of a $30 million financing.

23 Jun 2014

Overlooked DNA shuffling drives deadly paediatric brain tumour

One of the deadliest forms of paediatric brain tumour, Group 3 medulloblastoma, is linked to a variety of large-scale DNA rearrangements which all have the same overall effect on specific genes located on different chromosomes.

23 Jun 2014

Six-gene signature predicts survival after targeted therapy for NSCLC

The presence of a six-gene profile in the microRNA of patients with advanced non-squamous non-small-cell lung cancer predicts reduced survival likelihood after first-line treatment with targeted therapy followed by chemotherapy for disease progression, indicate research results.

20 Jun 2014

Greenlander study identifies single mutation with large diabetes risk

Researchers have used a Greenlandic cohort to identify a genetic mutation whose effect on the risk of diabetes is “several times larger” than any previously discovered.

20 Jun 2014

Insurers face difficult cost and coverage calculations regarding gene-sequencing tests

Aimee Robeson just wants an answer. Her son, Christian, was born in 2010 with multiple, mysterious syndromes that leave him unable to speak, chew, or walk on his own.

20 Jun 2014

Yap1 oncogene drives recurrence and progression of pancreatic cancer

Pancreatic cancer tumors addicted to mutant Kras signaling for their growth and progression have a ready-made substitute to tap if they're ever forced to go cold-turkey on the mutant oncogene, scientists at The University of Texas MD Anderson Cancer Center report in the journal Cell.

20 Jun 2014

New research reveals gene's role in type 1 diabetes

New research describes details of how a diabetes-related gene functions on a biological pathway that affects the release of insulin. The study authors say that finding drugs that act on that pathway may eventually lead to a new treatment for type 1 diabetes.

20 Jun 2014

Susceptibility gene for type 1 diabetes regulates self-destruction of cell's energy factory

A team led by researchers from the Perelman School of Medicine at the University of Pennsylvania found that a susceptibility gene for type 1 diabetes regulates self-destruction of the cell's energy factory. They report their findings this week in Cell.

20 Jun 2014

Scientists discover major breakthrough in cancer treatment

Scientists at the Sahlgrenska Academy, University of Gothenburg, have developed a new cancer treatment that has proved to be effective in mice. The treatment, which is presented in the prestigious scientific journal PNAS, is based on newly discovered properties of the so-called BET bromodomain inhibitors.

20 Jun 2014

Clinically relevant mouse model for difficult-to-treat squamous cell lung cancer

Only 15% of patients with squamous cell lung cancer - the second most common lung cancer - survive five years past diagnosis.

20 Jun 2014

Research provides unique insight into lncRNAs that regulate lung development

It's a long way from DNA to RNA to protein, and only about two percent of a person's genome is eventually converted into proteins.

19 Jun 2014

DNA sequencing does not reveal the pathogenicity of bacteria

While more and more genomic information is becoming available at a drastically increasing pace, the knowledge we can gain about how microorganisms interact with their surrounding, infect hosts and alter their molecular programs in accordance to changing environmental conditions remains widely not deducible from genomic data alone, the researchers from University of Southern Denmark claim.

19 Jun 2014

Researchers discover crucial process that regulates development of blood vessels

Biologists at The Scripps Research Institute (TSRI) have discovered a crucial process that regulates the development of blood vessels.

19 Jun 2014

Researchers find shared genetic link in autoimmune response among PV patients

Autoimmune disease occurs when the body's own natural defense system rebels against itself. One example is pemphigus vulgaris (PV), a blistering skin disease in which autoantibodies attack desmoglein 3 (Dsg3), the protein that binds together skin cells.

19 Jun 2014

Gene News and Research

Latest Gene News and Research

Research finding could open new opportunities for treating Huntington's disease

Colon has safety mechanism to restrict formation and growth of adenomas

Clusters of protein linked to cancer warp cell membranes

Researchers identify two oncogenes that drive the development of medulloblastoma

Investigators discover novel cellular genes by uncovering uncharacterized RNAs that encode proteins

Bayer, Dimension Therapeutics partner to develop new gene therapy for hemophilia A

Dimension Therapeutics closes $30M financing to advance novel gene therapy programs

Overlooked DNA shuffling drives deadly paediatric brain tumour

Six-gene signature predicts survival after targeted therapy for NSCLC

Greenlander study identifies single mutation with large diabetes risk

Insurers face difficult cost and coverage calculations regarding gene-sequencing tests

Yap1 oncogene drives recurrence and progression of pancreatic cancer

New research reveals gene's role in type 1 diabetes

Susceptibility gene for type 1 diabetes regulates self-destruction of cell's energy factory

Scientists discover major breakthrough in cancer treatment

Clinically relevant mouse model for difficult-to-treat squamous cell lung cancer

Research provides unique insight into lncRNAs that regulate lung development

DNA sequencing does not reveal the pathogenicity of bacteria

Researchers discover crucial process that regulates development of blood vessels

Researchers find shared genetic link in autoimmune response among PV patients

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