Gene News and Research

Latest Gene News and Research

Isis Pharmaceuticals reports final data from ISIS-APOCIIIRx Phase 2 study in patients with FCS

Isis Pharmaceuticals, Inc. announced the final data from its Phase 2 study of ISIS-APOCIIIRx as a monotherapy in patients with familial chylomicronemia syndrome, or FCS.

2 May 2014

New research suggests that Kindlin-3 regulates 2 major hallmarks of breast cancer

A protein believed to be limited to the hematopoietic system, called Kindlin-3, has been identified as a major player in both the formation and spread of breast cancer to other organs.

2 May 2014

Newly discovered molecule provides drug target for controlling both asthma and cancerous tumor growth

A newly discovered molecule provides a new drug target for controlling both asthma-induced muscle thickening and cancerous tumor growth. This molecule, called "microRNA-10a," normally helps genes produce proteins or make copies of themselves, also play an important role in the growth or overgrowth of human airway smooth muscle cells and some forms of cancer.

2 May 2014

Tel Aviv University pinpoints mechanism that causes rare and severe congenital syndrome

In the 1950s and 1960s, pregnant women with morning sickness were often prescribed the new drug thalidomide. Shortly after the medicine was released on the market, a reported 10,000 infants were born with an extreme form of the rare congenital phocomelia syndrome, which caused death in 50 percent of cases and severe physical and mental disabilities in others.

2 May 2014

Second Genome, Pfizer partner to conduct microbiome research to gain new insights into obesity

Second Genome announced today that it has entered into an agreement with Pfizer Inc. to conduct extensive microbiome research in a large observational study aimed at gaining new insights into obesity and metabolic disease.

2 May 2014

Scientists develop experimental drug that prolongs lifespan in mouse model of accelerated aging

Northwestern Medicine- scientists have newly identified a protein's key role in cell and physiological aging and have developed - in collaboration with Tohoku University in Japan -- an experimental drug that inhibits the protein's effect and prolonged the lifespan in a mouse model of accelerated aging.

2 May 2014

Enrichment of highly abundant epigenetic marks from endometrial stromal cells

Chromatrap®, the novel solid-based matrix for chromatin immunoprecipitation (ChIP) assays, available from Porvair Sciences, has been successfully used to isolate high quality chromatin from difficult biopsy material.

From Chromatrap® - Porvair Sciences Ltd 30 Apr 2014

Early gene therapy could improve choroideremia prognosis

Retinal gene therapy could prevent loss of vision in patients with choroideremia and other retinal diseases, show the results of a phase I/II study.

30 Apr 2014

Researchers create tiny, biodegradable nanoparticles that carry DNA to brain cancer cells

Working together, Johns Hopkins biomedical engineers and neurosurgeons report that they have created tiny, biodegradable “nanoparticles” able to carry DNA to brain cancer cells in mice.

30 Apr 2014

Vertex: Conditions of PBAC recommendation may limit Australians who could benefit from KALYDECO

The Pharmaceutical Benefits Advisory Committee has again recommended KALYDECO (ivacaftor) for listing on the Pharmaceutical Benefits Scheme (PBS). However, Vertex is deeply disappointed in the conditions the PBAC has attached to the recommendation. These conditions fail to reflect the substantial clinical benefits recognised by the PBAC, and would result in limiting the number of eligible Australians who would be able to receive KALYDECO.

30 Apr 2014

Mother's diet before conception can permanently affect how her child's genes function

A mother's diet before conception can permanently affect how her child's genes function, according to a study published in Nature Communications.

30 Apr 2014

3D shape of leukemia cell's genome holds key to solving puzzle of human diseases

To solve a puzzle, you need to recognize shapes, patterns and a particular kind of order. In much the same way, researchers at McGill University have discovered that the 3D shape of a leukemia cell's genome holds a key to solving the puzzle of human diseases. The researchers report their findings in the open access journal Genome Biology.

30 Apr 2014

Higher calcium intake appears to mitigate impact of some of the risk genes for type 2 diabetes

Study shows calcium intake mitigates genetic risk for increased body fat in African-American children, a population with historically low calcium intake and high risk for diabetes.

29 Apr 2014

Illumina launches VeriSeq PGS for preimplantation genetic screening of embryos

Illumina, Inc. today announced the launch of VeriSeq PGS, a next-generation sequencing solution developed for preimplantation genetic screening of embryos using Illumina's NextSeq 500 and MiSeq® sequencing systems.

From Illumina, Inc. 29 Apr 2014

Gene expression profiling tests play critical role in women’s chemotherapy decision

Gene expression profiling tests play a critical role when women with early-stage breast cancer decide whether to have chemotherapy, but many of them do not fully understand what some of the test results mean, new research suggests.

29 Apr 2014

Study: Genetics as well as environment in womb play important roles in development of baby

A recent study led by A*STAR's Singapore Institute for Clinical Sciences (SICS) found that genetics as well as the environment in the womb play important roles in the development of the baby.

29 Apr 2014

Mayo Clinic launches new gene panel cancer test to help tailor chemotherapy

Mayo Clinic announces the launch of CANCP, a new gene panel cancer test to help tailor chemotherapy to the individual patient based on the unique genomic signature of the patient's tumor.

29 Apr 2014

Study illustrates how patient's genes can affect drug reaction and dosage

A new study out of Western University (London, Canada) illustrates the need for a lot more education around pharmacogenetics (PGx) -the study of how a patient's genes can affect drug reaction and dosage.

29 Apr 2014

Scientists identify first gene linked to childhood-onset familial dilated cardiomyopathy

Scientists at Icahn School of Medicine at Mount Sinai, along with collaborators at institutions in India, Italy, and Japan, have identified the first gene linked to childhood-onset familial dilated cardiomyopathy (DCM), one of the most common heart muscle diseases in children.

29 Apr 2014

Study: Mutations could have major impact on treatment of human blood diseases

A study published today in Nature Genetics has revealed mutations that could have a major impact on the future diagnosis and treatment of many human diseases.

29 Apr 2014

Gene News and Research

Latest Gene News and Research

Isis Pharmaceuticals reports final data from ISIS-APOCIIIRx Phase 2 study in patients with FCS

New research suggests that Kindlin-3 regulates 2 major hallmarks of breast cancer

Newly discovered molecule provides drug target for controlling both asthma and cancerous tumor growth

Tel Aviv University pinpoints mechanism that causes rare and severe congenital syndrome

Second Genome, Pfizer partner to conduct microbiome research to gain new insights into obesity

Scientists develop experimental drug that prolongs lifespan in mouse model of accelerated aging

Enrichment of highly abundant epigenetic marks from endometrial stromal cells

Early gene therapy could improve choroideremia prognosis

Researchers create tiny, biodegradable nanoparticles that carry DNA to brain cancer cells

Vertex: Conditions of PBAC recommendation may limit Australians who could benefit from KALYDECO

Mother's diet before conception can permanently affect how her child's genes function

3D shape of leukemia cell's genome holds key to solving puzzle of human diseases

Higher calcium intake appears to mitigate impact of some of the risk genes for type 2 diabetes

Illumina launches VeriSeq PGS for preimplantation genetic screening of embryos

Gene expression profiling tests play critical role in women’s chemotherapy decision

Study: Genetics as well as environment in womb play important roles in development of baby

Mayo Clinic launches new gene panel cancer test to help tailor chemotherapy

Study illustrates how patient's genes can affect drug reaction and dosage

Scientists identify first gene linked to childhood-onset familial dilated cardiomyopathy

Study: Mutations could have major impact on treatment of human blood diseases

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