Gene News and Research

Latest Gene News and Research

Findings on molecular defects behind bladder cancer may pave way for new, targeted treatments

The once sketchy landscape of the molecular defects behind bladder cancer now resembles a road map to new, targeted treatments thanks to the unified efforts of scientists and physicians at 40 institutions.

30 Jan 2014

New insight into mammalian circadian rhythms could lead to therapies for metabolic disorders

We've all heard about circadian rhythm, the roughly 24-hour oscillations of biological processes that occur in many living organisms. Yet for all its influence in many aspects of our lives - from sleep to immunity and, particularly, metabolism - relatively little is understood about the mammalian circadian rhythm and the interlocking processes that comprise this complex biological clock.

30 Jan 2014

Bladder, lung cancers are marked by shared differences in genetics that control cell cycle

A University of Colorado Cancer Center study published in the journal PLoS ONE shows that bladder and lung cancers are marked by shared differences in the genetics that control the cell cycle.

30 Jan 2014

Vaccine to treat precancerous cervical lesions triggers immune cell response

Preliminary results of a small clinical trial show that a vaccine used to treat women with high-grade precancerous cervical lesions triggers an immune cell response within the damaged tissue itself.

30 Jan 2014

Dormant prostate cancer cells within bone tissue can be reawakened to a cancerous state

Dormant prostate cancer cells in bone tissue can be reawakened to cause secondary tumours, according to new research published in Endocrine-Related Cancer. Targeting the wake-up call could prevent metastasis and improve prostate cancer survival rates.

29 Jan 2014

Myriad Genetics' Prolaris opens door to a new era of personalized treatment for prostate cancer

Myriad Genetics, Inc. today announced results from PROCEDE 500, a clinical utility study with its Prolaris test, at the 2014 ASCO Genitourinary Cancers Symposium in San Francisco, Calif. The study demonstrated the significant clinical value of Prolaris to physicians who are treating men with prostate cancer. Prolaris is a prognostic test that accurately predicts prostate cancer-specific death and metastases and has been validated in 11 clinical studies with more than 5,000 patients.

29 Jan 2014

Susceptible loci identified for bipolar I disorder in Taiwanese

Researchers have identified three genetic loci that may be linked to bipolar I disorder risk in Taiwanese individuals.

29 Jan 2014

FARA funds gene therapy-based research project to tackle Friedreich's ataxia

The gene therapy-based research project to tackle Friedreich's ataxia launched in November in labs at the Institute for Research in Biomedicine, in Barcelona, and the "Centro de Biolog-a Molecular Severo Ochoa", in Madrid, has received 100,000 US$ per year for two years from the Friedreich's Ataxia Research Alliance.

29 Jan 2014

Researchers design semi-synthetic proteins to analyse body's vital signal processes

Proteins play a fundamental role in almost all biological processes. They consist of chains constructed of up to 20 different amino acids, and their composition, structure and function are controlled by the genetic code.

29 Jan 2014

CU receives cooperative agreement to develop technological system to determine effects chemical agents

The University of Colorado Boulder has been awarded a cooperative agreement worth up to $14.6 million from the Defense Advanced Research Projects Agency (DARPA) to develop a new technological system to rapidly determine how drugs and biological or chemical agents exert their effects on human cells.

29 Jan 2014

Researcher receives 2014 Japan Prize in Life Sciences for extraordinary work in the field of epigenetics

C. David Allis, a pioneer in the field of epigenetics whose discovery that chemical modifications of DNA-packaging proteins play a key role in regulating the activity of individual genes, will be awarded the 2014 Japan Prize in Life Sciences. The announcement, by the Japan Prize Foundation, was made at a press conference in Tokyo this morning.

29 Jan 2014

NEBioCalculator: New online tool offers support for molecular biology experiments

NEBioCalculator, a new online "conversions and calculations" tool developed by New England Biolabs, offers bench-side support for molecular biology experimental planning.

From New England Biolabs 29 Jan 2014

Study: Genetic mutations in titin gene can cause skeletal muscle disease

A University of Arizona doctoral candidate has shown for the first time that genetic mutations in the titin gene can cause skeletal muscle myopathy, a disease in which muscle fibers do not function properly, resulting in muscle weakness.

29 Jan 2014

Johns Hopkins researchers reveal how non-CpG methylation may contribute to Rett Syndrome

In normal development, all cells turn off genes they don’t need, often by attaching a chemical methyl group to the DNA, a process called methylation. Historically, scientists believed methyl groups could only stick to a particular DNA sequence: a cytosine followed by a guanine, called CpG. But in recent years, they have been found on other sequences, and so-called non-CpG methylation has been found in stem cells, and in neurons in the brain.

28 Jan 2014

New approach for reversing hair loss uses stem cells to regenerate missing hair follicles

If the content of many a situation comedy, not to mention late-night TV advertisements, is to be believed, there's an epidemic of balding men, and an intense desire to fix their follicular deficiencies.

28 Jan 2014

Researchers identify therapeutic target for cervix cancer

Gene related to the proliferation of cancerous cells blocked through molecular technology. A group of researchers from Mexico's General Hospital, Health Secretariat, Medicine Faculty and the Institute of Cellular Physiology of the National Autonomous University of Mexico (UNAM) identified a therapeutic target for cervix cancer: gene CDKN3.

28 Jan 2014

Researchers develop valid humanized model for facioscapulohumeral muscular dystrophy

Researchers at the Kennedy Krieger Institute recently announced study findings showing the successful development of a humanized preclinical model for facioscapulohumeral muscular dystrophy (FSHD), providing scientists with a much needed tool to accelerate novel therapeutic research and development.

28 Jan 2014

Gene News and Research

Latest Gene News and Research

Findings on molecular defects behind bladder cancer may pave way for new, targeted treatments

New insight into mammalian circadian rhythms could lead to therapies for metabolic disorders

Bladder, lung cancers are marked by shared differences in genetics that control cell cycle

Vaccine to treat precancerous cervical lesions triggers immune cell response

Dormant prostate cancer cells within bone tissue can be reawakened to a cancerous state

Myriad Genetics' Prolaris opens door to a new era of personalized treatment for prostate cancer

Susceptible loci identified for bipolar I disorder in Taiwanese

FARA funds gene therapy-based research project to tackle Friedreich's ataxia

Researchers design semi-synthetic proteins to analyse body's vital signal processes

CU receives cooperative agreement to develop technological system to determine effects chemical agents

Researcher receives 2014 Japan Prize in Life Sciences for extraordinary work in the field of epigenetics

NEBioCalculator: New online tool offers support for molecular biology experiments

Study: Genetic mutations in titin gene can cause skeletal muscle disease

Johns Hopkins researchers reveal how non-CpG methylation may contribute to Rett Syndrome

New approach for reversing hair loss uses stem cells to regenerate missing hair follicles

Researchers identify therapeutic target for cervix cancer

Researchers develop valid humanized model for facioscapulohumeral muscular dystrophy

Study provides possible clue to high rate of preterm labor after human fetal surgery

Researchers discover unusually large bacteriophage that infects anthrax bacterium

BioTime: OncoCyte initiates clinical development of bladder cancer diagnostic test in U.S, China

eBook: Using iPSCs models for human disease research and drug discovery eBook

Todd Bauman and Chris Povich

Scaling organ‑chip technology for human‑relevant drug discovery

Unlocking drug amorphization: Continuous, solvent-free twin screw granulation