Gene News and Research

Latest Gene News and Research

Researchers identify new mechanism by which normal cells turn malignant in mammary epithelial tissues

A team of researchers led by David J. Mooney, Robert P. Pinkas Family Professor of Bioengineering at the Harvard School of Engineering and Applied Sciences, have identified a possible mechanism by which normal cells turn malignant in mammary epithelial tissues, the tissues frequently involved in breast cancer.

17 Jun 2014

Autistic-like behaviors linked with disruption of Adenomatous Polyposis Coli gene

Autistic-like behaviors and decreased cognitive ability may be associated with disruption of the function of the Adenomatous Polyposis Coli (APC) gene.

17 Jun 2014

International researchers discover genetic component of Idiopathic Generalized Epilepsy

An international team of researchers has discovered a significant genetic component of Idiopathic Generalized Epilepsy (IGE), the most common form of epilepsy.

17 Jun 2014

Combination of effective drugs for Parkinson's disease controls symptoms of Rett syndrome in mice

IDIBELL researchers, led by the director of the Program for Epigenetics and Cancer Biology, ICREA researcher and Professor of Genetics at the University of Barcelona, Manel Esteller, have shown that a combination of effective drugs for Parkinson's disease in mice that are used as a model of human Rett syndrome reduces some of the symptoms associated with this disease.

17 Jun 2014

Type I interferons can block development of allergy- and asthma-driving Th2 cells

A mechanism that could underlie the development of cells that drive asthma and allergies has been uncovered by immunology researchers at UT-Southwestern Medical Center.

17 Jun 2014

Rice University scientists apply new theory to learn how and why cells differentiate

How does a stem cell decide what path to take? In a way, it's up to the wisdom of the crowd.

17 Jun 2014

Cepheid releases molecular test for detection of carbapenemase-producing Gram-negative bacteria

Cepheid today announced the release of Xpert® Carba-R, an on-demand molecular test for rapid and accurate detection of carbapenemase-producing Gram-negative bacteria, to be marketed as a CE IVD product under the European Directive on In Vitro Diagnostic Medical Devices.

16 Jun 2014

Counseling from genetic health care provider may help reduce unnecessary procedures

A new Moffitt Cancer Center study published Thursday in Genetics in Medicine shows that counseling from a genetic health care provider before genetic testing educates patients and may help reduce unnecessary procedures.

16 Jun 2014

Kids with rare mutations in two genes are 4 times more likely to develop severe scoliosis

Children with rare mutations in two genes are about four times more likely to develop severe scoliosis than their peers with normal versions of the genes, scientists have found.

16 Jun 2014

Researchers identify tremendous genetic diversity

In the most comprehensive genetic study of the Mexican population to date, researchers from UC San Francisco and Stanford University, along with Mexico's National Institute of Genomic Medicine (INMEGEN), have identified tremendous genetic diversity, reflecting thousands of years of separation among local populations and shedding light on a range of confounding aspects of Latino health.

13 Jun 2014

Researchers explain possibility of using biomarkers in children with JIA to predict status of disease

Data presented today at the European League Against Rheumatism Annual Congress (EULAR 2014) demonstrate the possibility of using biomarkers (developed from whole blood gene expression profiles) in children with juvenile idiopathic arthritis (JIA) to predict the status of their disease at 12 months.

13 Jun 2014

New genetic 'barcode' for malaria parasites could be used to track and contain spread of disease

A new genetic 'barcode' for malaria parasites has been found which could be used to track and contain the spread of the disease, according to new research led by the London School of Hygiene & Tropical Medicine.

13 Jun 2014

Tufts researchers gain new insight into protein associated with bipolar disorder

Researchers from Tufts have gained new insight into a protein associated with bipolar disorder. The study, published in the June 3 issue of Science Signaling, reveals that calcium channels in resting neurons activate the breakdown of Sp4, which belongs to a class of proteins called transcription factors that regulate gene expression.

12 Jun 2014

DNA methylation identified as potential anti-TNF response biomarker for RA

DNA methylation has been identified as a potential biomarker of response to etanercept and adalimumab in patients with rheumatoid arthritis (RA) according to preliminary results from one of the largest methylome-wide investigations of treatment response to anti-TNF therapies.

12 Jun 2014

People with obesity gene FTO tend to gain more weight as they age

A new study from Uppsala University demonstrates that elderly humans carrying a common variant of the fat mass and obesity gene FTO also have a shifted endocrine balance. Low blood concentrations of the satiety hormone leptin and high blood concentrations of the hunger promoting hormone ghrelin makes carriers of the FTO gene put on weight.

12 Jun 2014

Cancer drug offers protection against thrombosis

Case Western Reserve University researchers have discovered that an existing drug used to help cancer patients has the potential to protect thousands of others from the often-deadly impact of vascular clots.

12 Jun 2014

Researchers study structural aspects of DNA-particle/lipid interface directly using x-ray scattering

Scientists seeking ways to engineer the assembly of tiny particles measuring just billionths of a meter have achieved a new first-the formation of a single layer of nanoparticles on a liquid surface where the properties of the layer can be easily switched.

11 Jun 2014

Molecular mechanisms regulating tumour initiation in skin SCC uncovered

Advanced online publication in Nature: Researchers at the Université libre de Bruxelles, ULB uncover the molecular mechanisms regulating tumour initiation and cancer stem cells functions in skin squamous cell carcinoma.

11 Jun 2014

Celgene: OTEZLA phase III study for psoriatic arthritis meets primary endpoint

Celgene International Sàrl, a wholly-owned subsidiary of Celgene Corporation (NASDAQ:CELG), today announced results of additional analyses from the phase III clinical trials of OTEZLA, the Company's oral, selective inhibitor of phosphodiesterase 4 (PDE4).

11 Jun 2014

Gene variant that increases risk of type 2 diabetes identified in Latino individuals

A genetic analysis of DNA samples of approximately 3,700 Mexican and U.S. Latino individuals identified a gene variant that was associated with a 5-fold increase in the prevalence of type 2 diabetes, findings that may have implications for screening in this population, according to a study in the June 11 issue of JAMA, a diabetes theme issue.

11 Jun 2014

Gene News and Research

Latest Gene News and Research

Researchers identify new mechanism by which normal cells turn malignant in mammary epithelial tissues

Autistic-like behaviors linked with disruption of Adenomatous Polyposis Coli gene

International researchers discover genetic component of Idiopathic Generalized Epilepsy

Combination of effective drugs for Parkinson's disease controls symptoms of Rett syndrome in mice

Type I interferons can block development of allergy- and asthma-driving Th2 cells

Rice University scientists apply new theory to learn how and why cells differentiate

Cepheid releases molecular test for detection of carbapenemase-producing Gram-negative bacteria

Counseling from genetic health care provider may help reduce unnecessary procedures

Kids with rare mutations in two genes are 4 times more likely to develop severe scoliosis

Researchers identify tremendous genetic diversity

Researchers explain possibility of using biomarkers in children with JIA to predict status of disease

New genetic 'barcode' for malaria parasites could be used to track and contain spread of disease

Tufts researchers gain new insight into protein associated with bipolar disorder

DNA methylation identified as potential anti-TNF response biomarker for RA

People with obesity gene FTO tend to gain more weight as they age

Cancer drug offers protection against thrombosis

Researchers study structural aspects of DNA-particle/lipid interface directly using x-ray scattering

Molecular mechanisms regulating tumour initiation in skin SCC uncovered

Celgene: OTEZLA phase III study for psoriatic arthritis meets primary endpoint

Gene variant that increases risk of type 2 diabetes identified in Latino individuals

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