Gene News and Research

Latest Gene News and Research

Scientists demonstrate importance of Plvap gene in mammalian physiology

Dartmouth scientists have demonstrated the importance of the gene Plvap and the structures it forms in mammalian physiology in a study published in December by the journal Developmental Cell.

4 Jan 2013

Pfizer, Repligen sign licensing deal to advance spinal muscular atrophy program

Repligen Corporation announced today that it has entered into an exclusive worldwide licensing agreement with Pfizer Inc. to advance Repligen's spinal muscular atrophy (SMA) program, originally in-licensed from Families of SMA (FSMA).

3 Jan 2013

Trovagene, MD Anderson partner to detect transrenal BRAF mutations in metastatic cancers

Trovagene, Inc., a developer of transrenal molecular diagnostics, announced that it has entered into a clinical collaboration with The University of Texas MD Anderson Cancer Center to detect transrenal BRAF mutations in the urine of patients with advanced or metastatic cancers.

3 Jan 2013

Improving research on BPA chemical may lead to better guidelines for human health

Following a three-year study using more than 2,800 mice, a University of Missouri researcher was not able to replicate a series of previous studies by another research group investigating the controversial chemical BPA. The MU study is not claiming that BPA is safe, but that the previous series of studies are not reproducible.

3 Jan 2013

Prenatal brain development may be important influence on psychiatric risk later in life

Some brain changes that are found in adults with common gene variants linked to disorders such as Alzheimer's disease, schizophrenia, and autism can also be seen in the brain scans of newborns.

3 Jan 2013

Refined mapping finds over 200 Crohn’s Disease genes

Researchers have used a genetic mapping technique to identify more than 200 genes associated with Crohn’s Disease, making it the most well-characterized disorder to date.

31 Dec 2012

Females students drink more intensively in shorter periods of time

Researchers from the HealthyFit group at the University of Vigo have studied university students' lifestyles; their analysis, which includes alcohol and illegal drug consumption habits, sport and food, concludes that most students indulge in unhealthy behaviour. One of the main results of the study is the high consumption of alcohol.

29 Dec 2012

New light on how epigenetic signals may function together to determine fate of stem cell

Long-standing research efforts have been focused on understanding how stem cells, cells capable of transforming into any type of cell in the body, are capable of being programmed down a defined path to contribute to the development of a specific organ like a heart, lung, or kidney. Research from the University of North Carolina at Chapel Hill School of Medicine has shed new light on how epigenetic signals may function together to determine the ultimate fate of a stem cell.

28 Dec 2012

Researchers sequence entire gene to identify mutations that cause hyperinsulinism

Congenital hyperinsulinism is a genetic condition where a baby's pancreas secretes too much insulin. It affects approximately one in 50,000 live births and in severe cases requires the surgical removal of all or part of the pancreas.

28 Dec 2012

Novel approach to sort out good or bad mutations associated with lymphoma

As anyone familiar with the X-Men knows, mutants can be either very good or very bad - or somewhere in between. The same appears true within cancer cells, which may harbor hundreds of mutations that set them apart from other cells in the body; the scientific challenge has been to figure out which mutations are culprits and which are innocent bystanders.

28 Dec 2012

Trovagene adds Duke University Health System to worldwide licensees of NPM1 marker for AML

Trovagene, Inc., a developer of transrenal molecular diagnostics, announced it has granted Duke University and Duke University Health Systems a non-exclusive license to incorporate nucleophosmin protein (NPM1) into research and clinical testing services for acute myelogenous leukemia (AML).

27 Dec 2012

Researchers reveal critical role of BRCA1 gene in maintenance of hair follicle stem cells

Our DNA, which stores our genetic information, is constantly submitted to damage. If not properly repaired, DNA damage can lead to cell death, which may in turn lead to tissue exhaustion and ageing, or induce mutations resulting in uncontrolled cell proliferation and cancer. Brca1 is a key gene that mediates DNA repair. Mutations in Brca1 lead to familial and sporadic breast and ovarian cancer in humans.

27 Dec 2012

Experiencing domestic violence may lead to mental health disorders

Men and women with mental health disorders, across all diagnoses, are more likely to have experienced domestic violence than the general population, according to new research from King's College London's Institute of Psychiatry, in collaboration with the University of Bristol. Previous studies into the link between domestic violence and mental health problems have mainly focused on depression, but this is the first study to look at a wide range of mental health problems in both male and female victims.

27 Dec 2012

Implementation of appropriateness criteria required for elective procedures

Many of the most common inpatient surgeries in the United States are performed electively. These surgeries are expected to significantly increase with the enactment of the Affordable Care Act.

27 Dec 2012

Study reveals body's food clock on a molecular level

If the sinful excess of holiday eating sends your system into butter-slathered, brandy-soaked overload, you are not alone: People who are jet-lagged, people who work graveyard shifts and plain-old late-night snackers know just how you feel.

25 Dec 2012

Study suggests genetic component in pain response among children

At least two common gene variants are linked to "clinically meaningful" differences in pain scores in children after major surgery, reports a study in the January issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society (IARS).

25 Dec 2012

Cancer-associated inflammation boosts ADAR1 enzyme activity

An international team, headed by researchers at the University of California, San Diego School of Medicine, has identified a key enzyme in the reprogramming process that promotes malignant stem cell cloning and the growth of chronic myeloid leukemia (CML), a cancer of the blood and marrow that experts say is increasing in prevalence.

25 Dec 2012

Gene News and Research

Latest Gene News and Research

Scientists demonstrate importance of Plvap gene in mammalian physiology

Pfizer, Repligen sign licensing deal to advance spinal muscular atrophy program

Trovagene, MD Anderson partner to detect transrenal BRAF mutations in metastatic cancers

Improving research on BPA chemical may lead to better guidelines for human health

Prenatal brain development may be important influence on psychiatric risk later in life

Refined mapping finds over 200 Crohn’s Disease genes

Females students drink more intensively in shorter periods of time

New light on how epigenetic signals may function together to determine fate of stem cell

Researchers sequence entire gene to identify mutations that cause hyperinsulinism

Novel approach to sort out good or bad mutations associated with lymphoma

Trovagene adds Duke University Health System to worldwide licensees of NPM1 marker for AML

Researchers reveal critical role of BRCA1 gene in maintenance of hair follicle stem cells

Experiencing domestic violence may lead to mental health disorders

Implementation of appropriateness criteria required for elective procedures

Study reveals body's food clock on a molecular level

Study suggests genetic component in pain response among children

Cancer-associated inflammation boosts ADAR1 enzyme activity

Cause of recurrent infections in MECP2 duplication syndrome identified

Genetic innovations for pneumonia diagnosis in children

Parkinson’s: an interview with Steve Ford, CEO of Parkinson’s UK

eBook: Using iPSCs models for human disease research and drug discovery eBook

How can super-resolution technology help study neurotransmission?

The Proteoform Puzzle: Unlocking the Next Frontier

Synthetic Biology and the Pursuit of Living Diagnostics