Gene News and Research

Latest Gene News and Research

NanoString Technologies to present clinical study of Prosigna Breast Cancer Assay at ASCO 2013

NanoString Technologies, Inc., a privately held provider of life science tools for translational research and molecular diagnostic products, today announced that a clinical study of the Prosigna Breast Cancer Assay will be presented during the Breast Cancer Oral Abstract Session at the 2013 Annual American Society of Clinical Oncology Meeting on Sunday, June 2.

From NanoString Technologies 1 Jun 2013

International researchers find how brain cancer cells survive and drive tumor growth

An international team of researchers - led by principal investigator Paul S. Mischel, MD, a member of the Ludwig Institute for Cancer Research and professor in the Department of Pathology at the University of California, San Diego School of Medicine - has found that a singular gene mutation helps brain cancer cells to not just survive, but grow tumors rapidly by altering the splicing of genes that control cellular metabolism.

1 Jun 2013

Plants to teach robots how to work together

John Innes Centre scientists will participate in new -2 million EU-funded research to programme more "intelligent" and adaptable robot swarms.

1 Jun 2013

Researchers discover potential biomarkers to identify patients with head and neck cancer

Researchers from Fox Chase Cancer Center will present data at the 49th Annual Meeting of the American Society of Clinical Oncology on Saturday, June 1, which shows the discovery of potential biomarkers that may be used to identify patients with head and neck cancer whose tumors are unlikely to respond to treatment by the targeted therapy cetuximab-a type of monoclonal antibody.

1 Jun 2013

Findings could potentially lead to new drug therapy for Cushing disease

Cushing disease is a life-threatening disorder most commonly triggered by tumors, often benign, in the pituitary glands, resulting in excess production of adrenocorticotrophic hormone.

1 Jun 2013

Study points to synergistic relationship between lead exposure and schizophrenia gene

Mice engineered with a human gene for schizophrenia and exposed to lead during early life exhibited behaviors and structural changes in their brains consistent with schizophrenia.

1 Jun 2013

New nanoparticle gene delivery method to prevent stenting procedure complications

Stent angioplasty saves lives, but there often are side effects and complications related to the procedure, such as arterial restenosis and thrombosis. In the June 2013 issue of The FASEB Journal, however, scientists report that they have discovered a new nanoparticle gene delivery method that may overcome current limitations of gene therapy vectors and prevent complications associated with the stenting procedure.

1 Jun 2013

Researchers develop new gene therapy to thwart potential influenza pandemic

Researchers at the Perelman School of Medicine, University of Pennsylvania have developed a new gene therapy to thwart a potential influenza pandemic. Specifically, investigators in the Gene Therapy Program, Department of Pathology and Laboratory Medicine, directed by James M. Wilson, MD, PhD, demonstrated that a single dose of an adeno-associated virus expressing a broadly neutralizing flu antibody into the nasal passages of mice and ferrets gives them complete protection and substantial reductions in flu replication when exposed to lethal strains of H5N1 and H1N1 flu virus.

30 May 2013

Cedars-Sinai team awarded grant to study cardiac stem cell treatment for Duchenne muscular dystrophy

Newport Beach-based nonprofit Coalition Duchenne has awarded a $150,000 grant to a Cedars-Sinai Heart Institute team investigating whether an experimental cardiac stem cell treatment could be used to treat Duchenne muscular dystrophy patients who have developed heart disease.

30 May 2013

Scientists find that 'junk DNA' could promote cancer progression

Scientists at The University of Nottingham have found that a genetic rogue element produced by sequences until recently considered 'junk DNA' could promote cancer progression.

30 May 2013

Gene therapy techniques show promise in promoting growth of skin, bone and other tissues

Experimental genetic techniques may one day provide plastic and reconstructive surgeons with an invaluable tool-the ability to promote growth of the patient's own tissues for reconstructive surgery.

30 May 2013

Tafinlar, Mekinist get FDA approval to treat patients with advanced melanoma

The U.S. Food and Drug Administration today approved two new drugs, Tafinlar (dabrafenib) and Mekinist (trametinib), for patients with advanced (metastatic) or unresectable (cannot be removed by surgery) melanoma, the most dangerous type of skin cancer.

30 May 2013

Viewpoints: 'Good news' on Calif. insurance rates; Battle against dementia needs stronger efforts; Dental care for the disabled

The Affordable Care Act, a k a Obamacare, goes fully into effect at the beginning of next year, and predictions of disaster are being heard far and wide. ... No doubt there will be problems, as there are with any large new government initiative, and in this case, we have the added complication that many Republican governors and legislators are doing all they can to sabotage reform. Yet important new evidence - especially from California, the law's most important test case - suggests that the real Obamacare shock will be one of unexpected success (Paul Krugman, 5/26).

29 May 2013

$2 million grant to provide instrumentation, core facilities devoted to synthetic biology

The Roy J. Carver Charitable Trust has awarded a $2 million grant to the Institute for Genomic Biology at the University of Illinois at Urbana-Champaign. Under the leadership of Principal Investigator Dr. Huimin Zhao and co-Principal Investigator Dr. Christopher Rao, the grant will be disbursed over two years to provide instrumentation and core facilities for a new research theme devoted to the new scientific subdiscipline of synthetic biology.

29 May 2013

Scientists identify role of GSK-3 alpha protein in promoting oncogenic KRAS function

While the mutated KRAS oncogene is associated with many cancers, it has not yet been successfully targeted by a therapeutic agent. Scientists are trying to find another way to target the gene by blocking signals from another protein downstream.

29 May 2013

Research discovery may lead to development of new therapies for neurological disorders

For several years, the pharmaceutical industry has tried to develop drugs that target a specific neurotransmitter receptor in the brain, the NMDA receptor. This receptor is present on almost every neuron in the human brain and is involved in learning and memory. NMDA receptors also have been implicated in several neurological and psychiatric conditions such as Alzheimer's disease, Parkinson's disease, schizophrenia and depression.

29 May 2013

Gene News and Research

Latest Gene News and Research

NanoString Technologies to present clinical study of Prosigna Breast Cancer Assay at ASCO 2013

International researchers find how brain cancer cells survive and drive tumor growth

Plants to teach robots how to work together

Researchers discover potential biomarkers to identify patients with head and neck cancer

Findings could potentially lead to new drug therapy for Cushing disease

Study points to synergistic relationship between lead exposure and schizophrenia gene

New nanoparticle gene delivery method to prevent stenting procedure complications

Researchers develop new gene therapy to thwart potential influenza pandemic

Cedars-Sinai team awarded grant to study cardiac stem cell treatment for Duchenne muscular dystrophy

Scientists find that 'junk DNA' could promote cancer progression

Gene therapy techniques show promise in promoting growth of skin, bone and other tissues

Tafinlar, Mekinist get FDA approval to treat patients with advanced melanoma

Viewpoints: 'Good news' on Calif. insurance rates; Battle against dementia needs stronger efforts; Dental care for the disabled

$2 million grant to provide instrumentation, core facilities devoted to synthetic biology

Scientists identify role of GSK-3 alpha protein in promoting oncogenic KRAS function

Research discovery may lead to development of new therapies for neurological disorders

Harmless genetic variations may team up to increase risk of schizophrenia, find researchers

Chromatrap® ChIP assay kit enriches epigenetic marks from primary human tissue cells

Mosquito repellent and human odour: an interview with Dr James Logan, London School of Hygiene & Tropical Medicine

Synthetic compound derived from sea anemone toxin shows potential to treat obesity

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

A new method to measure intracellular water in biological systems

Obesity, GLP-1s, and metabolic care