Gene News and Research

Latest Gene News and Research

Researchers discover genetics secrets of ovarian cancer tumors

A new discovery that sheds light on the genetic make up of ovarian cancer cells could explain why some women survive longer than others with this deadly disease.

25 Sep 2012

NVIDIA video cards can help reduce radiation exposure from X-ray and CT scans

Video gamers are generally the biggest consumers of computer graphics cards, using the devices to boost the speed and resolution of their digital quests to fend off invading extraterrestrials or outwit hostile dragons. But researchers at Rensselaer Polytechnic Institute seek to harness the power of these computer graphics cards to solve one of the world's most pressing health care technology challenges: radiation exposure from X-ray and CT imaging scans.

25 Sep 2012

New KSU molecule may deliver drugs inside the body to treat diseases

Kansas State University researchers have discovered a molecule that may be capable of delivering drugs inside the body to treat diseases.

25 Sep 2012

University of Iowa, Mayo Clinic to continue SPORE for lymphoma research

The Mayo Clinic Cancer Center and Holden Comprehensive Cancer Center at the University of Iowa have received a five-year, $11.5 million grant renewal from the National Cancer Institute (NCI) to continue the Specialized Program of Research Excellence (SPORE) for lymphoma research.

25 Sep 2012

Small fragments of keratin protein in the eye play a key role in warding off pathogens

When it comes to germ-busting power, the eyes have it, according to a discovery by University of California, Berkeley, researchers that could lead to new, inexpensive antimicrobial drugs.

25 Sep 2012

New clinical trial to evaluate DEX-M74 against hereditary inclusion body myopathy

Researchers have launched a clinical trial to evaluate the drug candidate DEX-M74 as a treatment for a rare degenerative muscle disease, hereditary inclusion body myopathy (HIBM). National Institutes of Health scientists from the National Center for Advancing Translational Sciences (NCATS) and the National Human Genome Research Institute (NHGRI) will conduct the clinical trial at the NIH Clinical Center.

25 Sep 2012

Anti-cancer EGFR inhibitors effective in reversing memory loss in animal models of Alzheimer's

A team of neuroscientists and chemists from the U.S. and China today publish research suggesting that a class of currently used anti-cancer drugs as well as several previously untested synthetic compounds show effectiveness in reversing memory loss in two animal models of Alzheimer's disease.

25 Sep 2012

PAM50 potentially simplifies underlying breast tumor biology

On September 23, researchers published online in the journal Nature a study of the molecular biology of breast cancer, using the intrinsic subtypes as defined by the PAM50 gene signature as an organizing framework for analyzing genomic and proteomic aberrations. This landmark study both underscores the emergence of the intrinsic subtypes as a powerful taxonomy of breast cancer in research, and PAM50's role as the gold standard for categorizing breast cancer by subtype.

From NanoString Technologies 25 Sep 2012

Lonafarnib proves effective for children with progeria

Results of the first-ever clinical drug trial for children with Progeria, a rare, fatal "rapid-aging" disease, demonstrate the efficacy of a farnesyltransferase inhibitor (FTI), a drug originally developed to treat cancer. The clinical trial results, completed only six years after scientists identified the cause of Progeria, included significant improvements in weight gain, bone structure and, most importantly, the cardiovascular system, according to The Progeria Research Foundation (PRF) and Boston Children's Hospital.

25 Sep 2012

Researchers identify gene linked to common cause of lower back pain

Researchers at King's College London have for the first time identified a gene linked to age-related degeneration of the intervertebral discs in the spine, a common cause of lower back pain.

24 Sep 2012

Conceptually novel mechanism for biological regulation of cell suicide

Death plays a big role in keeping things alive. Consider the tightly orchestrated suicide of cells--a phenomenon essential to everything from shaping an embryo to keeping it free of cancer later in life. When cells refuse to die, and instead multiply uncontrollably, they become what we call tumors. An intricate circuitry of biochemical reactions inside cells coordinates their self-sacrifice. Tracing that circuitry is, naturally, an important part of cancer research.

24 Sep 2012

Biologists unravel why some people infected with HIV have more virus

Biologists at UC San Diego have unraveled the anti-viral mechanism of a human gene that may explain why some people infected with HIV have much higher amounts of virus in their bloodstreams than others.

24 Sep 2012

RXi completes dosing in RXI-109 Phase 1 study for dermal scarring

RXi Pharmaceuticals Corporation, a biotechnology company focused on discovering, developing and commercializing innovative therapies addressing major unmet medical needs using RNA-targeted technologies, today announced that dosing with their first drug in its first Phase 1 study, was completed last week.

24 Sep 2012

$Encouraging results from CTI’s pacritinib phase 1 study on relapsed/refractory lymphoma$

Encouraging results from CTI’s pacritinib phase 1 study on relapsed/refractory lymphoma

Cell Therapeutics, Inc. announced today that the phase 1 study data of its highly selective oral JAK2 inhibitor pacritinib, or SB1518, showed encouraging anti-tumor activity and good tolerability in 34 patients with relapsed/refractory lymphoma.

24 Sep 2012

Researchers identify subgroups of B cells in MYC-positive germinal centers

Germinal centers are sites in the organs of the lymphatic system, formed during the course of an immune response to infection, where B cells intensely proliferate and modify their DNA in order to produce antibodies specific for the pathogen. However, it is known that the vast majority of lymphomas derive from the B cells at the germinal centers.

24 Sep 2012

Most basal-like breast and ovarian tumors have similar genetic origins

The most comprehensive analysis yet of breast cancer shows that one of the most deadly subtypes is genetically more similar to ovarian tumors than to other breast cancers.

24 Sep 2012

Natural killer cells may influence lung cancer susceptibility

Why do many heavy smokers evade lung cancer while others who have never lit up die of the disease? The question has vexed scientists for decades.

24 Sep 2012

New mouse models can help scientists study SECISBP2 syndrome

New mouse models can help scientists study a rare disease, called SECISBP2 syndrome, that causes abnormal thyroid hormone metabolism, delayed bone maturation, as well as other abnormal characteristics that vary by individual, according to new data presented at the 82nd Annual Meeting of the American Thyroid Association (ATA) in Québec City, Québec, Canada.

24 Sep 2012

Genomic analysis of E. coli shows multiple steps to evolve new trait

Several years ago researchers at Michigan State University (MSU) reported discovering a novel, evolutionary trait in a long-studied population of Escherichia coli, a rod-shaped bacterium commonly found in the lower intestine of mammals. The E. coli added a helping of citrate to its traditional diet of glucose, even though other E. coli can't consume citrate in the presence of oxygen.

24 Sep 2012

FSU researcher to explore gene-controlling effects of addictive drugs in pursuit of new HIV treatments

A Florida State University researcher is on a mission to explore the gene-controlling effects of addictive drugs in pursuit of new HIV treatments.

24 Sep 2012

Gene News and Research

Latest Gene News and Research

Researchers discover genetics secrets of ovarian cancer tumors

NVIDIA video cards can help reduce radiation exposure from X-ray and CT scans

New KSU molecule may deliver drugs inside the body to treat diseases

University of Iowa, Mayo Clinic to continue SPORE for lymphoma research

Small fragments of keratin protein in the eye play a key role in warding off pathogens

New clinical trial to evaluate DEX-M74 against hereditary inclusion body myopathy

Anti-cancer EGFR inhibitors effective in reversing memory loss in animal models of Alzheimer's

PAM50 potentially simplifies underlying breast tumor biology

Lonafarnib proves effective for children with progeria

Researchers identify gene linked to common cause of lower back pain

Conceptually novel mechanism for biological regulation of cell suicide

Biologists unravel why some people infected with HIV have more virus

RXi completes dosing in RXI-109 Phase 1 study for dermal scarring

Encouraging results from CTI’s pacritinib phase 1 study on relapsed/refractory lymphoma

Researchers identify subgroups of B cells in MYC-positive germinal centers

Most basal-like breast and ovarian tumors have similar genetic origins

Natural killer cells may influence lung cancer susceptibility

New mouse models can help scientists study SECISBP2 syndrome

Genomic analysis of E. coli shows multiple steps to evolve new trait

FSU researcher to explore gene-controlling effects of addictive drugs in pursuit of new HIV treatments

eBook: Using iPSCs models for human disease research and drug discovery eBook

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting