Gene News and Research

Latest Gene News and Research

Berkeley lab researchers link possible new oncogene with resistance to cancer drugs

A gene that may possibly belong to an entire new family of oncogenes has been linked by researchers with the U.S. Department of Energy (DOE)'s Lawrence Berkeley National Laboratory (Berkeley Lab) to the resistance of breast cancer to a well-regarded and widely used cancer therapy.

12 Sep 2012

Genetic test predicts risk for Autism

A team of Australian researchers, led by University of Melbourne has developed a genetic test that is able to predict the risk of developing Autism Spectrum Disorder, ASD.

11 Sep 2012

Karolinska Institutet professor receives Fernström Foundation Nordic Prize for obesity research

This year's Fernström Foundation Nordic Prize, worth SEK 1 million, goes to Professor Peter Arner from Karolinska Institutet, Sweden, who conducts research on fat. His team was the first to show that fat cells are formed throughout one's lifetime, not just in childhood.

11 Sep 2012

Two National University of Singapore scientists win Lasker Awards for medical research

Two scientists from the National University of Singapore (NUS) - Professor Michael Sheetz, Director of the Mechanobiology Institute of Singapore; and Professor Roy Calne, Visiting Professor with the NUS Yong Loo Lin School of Medicine's Department of Surgery - have been conferred the prestigious Lasker Awards for making great advances in medical research.

11 Sep 2012

KRAS gene mutation recruits second player to trigger pancreatic cancer

More than a cancer-causing gene is needed to trigger pancreatic cancer, a study led by Mayo Clinic has found. A second factor creates a "perfect storm" that allows tumors to form, the researchers say. The study, published in the Sept. 10 issue of Cancer Cell, overturns the current belief that a mutation in the KRAS oncogene is enough to initiate pancreatic cancer and unrestrained cell growth.

11 Sep 2012

U of I microbial engineer synthesizes 2-fucosyllactose to protect babies from pathogens

A University of Illinois microbial engineer has synthesized a sugar in human milk that is thought to protect babies from pathogens. That's important because 2FL, the shorthand scientists use to describe this human milk oligosaccharide (HMO), has not been added to infant formula because HMOs are incredibly expensive.

11 Sep 2012

MicroRNA-145 gene therapy can drastically reduce severity and progression of atherosclerosis

Researchers at St. Michael's Hospital are one step closer to understanding why plaque bursts in coronary arteries and causes heart attacks.

11 Sep 2012

Study discovers pathways that govern instability of GAA/TTC repeats

A study of more than 6,000 genes in a common species of yeast has identified the pathways that govern the instability of GAA/TTC repeats. In humans, the expansions of these repeats is known to inactivate a gene - FXN - which leads to Friedreich's ataxia, a neurodegenerative disease that is currently incurable. In yeast, long repeats also destabilize the genome, manifested by the breakage of chromosomes.

11 Sep 2012

Researchers gain new insight into regulation of adult nerve cell generation in the hypothalamus

Researchers from the University of Utah have gained new insight into the regulation of adult nerve cell generation in the hypothalamus, the part of the brain that regulates many aspects of behavior, mood, and metabolism.

11 Sep 2012

P5091 molecule triggers apoptosis in drug-resistant myeloma cells

A molecule that targets the cell's machinery for breaking down unneeded proteins can kill multiple myeloma cancer cells resistant to the frontline drug Velcade, researchers at Dana-Farber Cancer Institute have found.

11 Sep 2012

Researchers discover small DNA sequence that drives GATA2 protein

The protein GATA2 is known as a "master regulator" of blood cell development. When a mutation occurs in the gene that makes GATA2, serious blood diseases such as acute myeloid leukemia can result.

11 Sep 2012

Data from Sangamo BioSciences’ SB-728-T Phase 1 clinical programs on HIV/AIDS

Sangamo BioSciences, Inc. announced that data from its Phase 1 clinical programs to develop SB-728-T, a novel therapeutic approach designed to generate a "functional cure" for HIV/AIDS, were presented at the 52nd Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC).

11 Sep 2012

Flow cytometry renders PCR testing unnecessary for most AML patients

Early treatment response is a powerful predictor of long-term outcome for young patients with acute myeloid leukemia (AML). The information can help physicians decide whether a more intensive approach is needed. Research led by St. Jude Children's Research Hospital investigators has identified the best test for measuring that response and guiding therapy.

11 Sep 2012

HIF-1 activity directly responsible for spread of breast cancer to lymph vessels

The invasion of cancer cells into the lymph vessels that connect the breast to surrounding lymph nodes is the first step leading to the metastasis, or spread, of cancer throughout the body. Metastasis is the primary cause of breast cancer deaths. Surprisingly little is known about the control of this process and how it might be interrupted to prolong the lives of women with breast cancer.

11 Sep 2012

Combining two drugs may offer new and potent punch against cancer and other diseases

A new study by researchers at Weill Cornell Medical College shows combining two already-FDA approved drugs may offer a new and potent punch against diseases in which blood vessel growth is abnormal -- such as cancer, diabetic retinopathy, macular degeneration and rheumatoid arthritis.

11 Sep 2012

Oxyphenbutazone can kill drug resistant TB

An off-patent anti-inflammatory drug that costs around two cents for a daily dose in developing countries has been found by researchers at Weill Cornell Medical College to kill both replicating and non-replicating drug resistant tuberculosis in the laboratory -- a feat few currently approved TB drugs can do, and resistance to those is spreading.

11 Sep 2012

Sifting through the junk with ENCODE

The first large-scale results from the ENCylopedia Of DNA Elements Consortium have shed light on possible functions of large areas of the genome previously thought of as “junk DNA.”

10 Sep 2012

Automated system for mapping protein-DNA interactions

Since the sequencing of the human genome in 2001, all our genes - around 20,000 in total - have been identified. But much is still unknown - for instance where and when each is active. Next to each gene sits a short DNA segment, and the activity of this regulatory segment determines whether the gene will be turned on, where and how strongly.

10 Sep 2012

Researchers identify many potential therapeutic targets for squamous cell lung cancers

A new paper published online in Nature holds out hope that people with the second most common type of lung cancer may one day benefit from targeted therapies that have transformed treatments for other lung cancer patients.

10 Sep 2012

Study measures cost-effectiveness of on-site rapid HIV testing in drug abuse treatment programs

Less than half of community-based substance abuse treatment programs in the United States currently make HIV testing available on-site or through referral. A new study led by researchers at Weill Cornell Medical College shows the cost-effectiveness of integrating on-site rapid HIV testing into drug treatment programs.

10 Sep 2012

Gene News and Research

Latest Gene News and Research

Berkeley lab researchers link possible new oncogene with resistance to cancer drugs

Genetic test predicts risk for Autism

Karolinska Institutet professor receives Fernström Foundation Nordic Prize for obesity research

Two National University of Singapore scientists win Lasker Awards for medical research

KRAS gene mutation recruits second player to trigger pancreatic cancer

U of I microbial engineer synthesizes 2-fucosyllactose to protect babies from pathogens

MicroRNA-145 gene therapy can drastically reduce severity and progression of atherosclerosis

Study discovers pathways that govern instability of GAA/TTC repeats

Researchers gain new insight into regulation of adult nerve cell generation in the hypothalamus

P5091 molecule triggers apoptosis in drug-resistant myeloma cells

Researchers discover small DNA sequence that drives GATA2 protein

Data from Sangamo BioSciences’ SB-728-T Phase 1 clinical programs on HIV/AIDS

Flow cytometry renders PCR testing unnecessary for most AML patients

HIF-1 activity directly responsible for spread of breast cancer to lymph vessels

Combining two drugs may offer new and potent punch against cancer and other diseases

Oxyphenbutazone can kill drug resistant TB

Sifting through the junk with ENCODE

Automated system for mapping protein-DNA interactions

Researchers identify many potential therapeutic targets for squamous cell lung cancers

Study measures cost-effectiveness of on-site rapid HIV testing in drug abuse treatment programs

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

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