Gene News and Research

Latest Gene News and Research

Researchers identify gene mutations responsible for subtype of childhood brain tumor

The St. Jude Children's Research Hospital - Washington University Pediatric Cancer Genome Project has identified mutations responsible for more than half of a subtype of childhood brain tumor that takes a high toll on patients.

15 Apr 2013

Researchers study gene that contributes to late-onset Alzheimer's disease in African-Americans

Researchers at Mayo Clinic in Florida participated in a nationwide study that found minor differences between genes that contribute to late-onset Alzheimer's disease in African-Americans and in Caucasians.

15 Apr 2013

Johns Hopkins researchers to highlight progress in genetic research at international meeting

Johns Hopkins genetics researchers Aravinda Chakravarti, Ph.D., and David Valle, M.D., will each present at the joint conference of the Human Genome Meeting 2013 and the 21st International Congress of Genetics.

15 Apr 2013

Death of heart tissue could be prevented with new medicines, say TUSM scientists

A major factor in the advance of heart disease is the death of heart tissue, a process that a team of scientists at Temple University School of Medicine's Center for Translational Medicine think could be prevented with new medicines.

15 Apr 2013

Scientists use mouse model to identify novel cell surface marker on mammary gland stem cells

Stem cells are different from all other cells in our body because they retain the remarkable genetic plasticity to self-renew indefinitely as well as develop into cell types with more specialized functions. However, this remarkable self-renewal capacity comes with a price, as stem cells can become seeds of cancer.

15 Apr 2013

Novel nanoparticle-based approach enables more efficient delivery of siRNA drugs

New classes of drugs that can silence specific genes, such as small interfering RNAs (siRNAs), offer great therapeutic potential. But the specific delivery of siRNAs to target cells to exert their effects remains a significant challenge. A novel nanoparticle-based approach that enables more efficient delivery of siRNA drugs is presented in Nucleic Acid Therapeutics, a peer-reviewed journal from Mary Ann Liebert, Inc. publishers.

12 Apr 2013

Study reveals inner workings of master regulator that controls diverse functions

New discoveries by a team of scientists at LSU Health Sciences Center New Orleans for the first time reveal the inner workings of a master regulator that controls functions as diverse as the ability of nerve cells to "rewire" themselves in response to external stimuli and the mechanism by which certain viruses hijack normal cellular processes to facilitate their replication that can ultimately lead to cancer. The research will be published in the April 12, 2013 issue of the Journal of Biological Chemistry.

12 Apr 2013

Study shows more women develop chronic low back pain, sciatica than men

More women than men develop chronic low back pain and sciatica. The explanation may lie with a gene variant that plays into the body's pain regulation.

12 Apr 2013

Researchers identify new potential therapeutic target for lowering cholesterol

Researchers at the University of Michigan have identified a new potential therapeutic target for lowering cholesterol that could be an alternative or complementary therapy to statins.

12 Apr 2013

Sanofi launches large-scale production of artemisinin for malaria

Twelve years after a breakthrough discovery in his University of California, Berkeley, laboratory, professor of chemical engineering Jay Keasling is seeing his dream come true.

12 Apr 2013

ATSP-9172 exhibits on-target binding activity in human prostate cancer model

Aileron Therapeutics, Inc. today announced new preclinical data demonstrating that ATSP-9172, its Stapled Peptide inhibitor of HIF-1α-dependent transcription, exhibits on-target binding activity, favorable pharmacokinetic properties and potent in vivo efficacy in a human prostate cancer model.

12 Apr 2013

Antipsychotics seemed to normalize gene expression pattern in people with bipolar disorder: Study

Every day, millions of people with bipolar disorder take medicines that help keep them from swinging into manic or depressed moods.

12 Apr 2013

Researchers identify two specific tumor suppressor genes associated with breast cancer

Research led by Dr. Suresh Alahari, Professor of Biochemistry and Molecular Biology at LSU Health Sciences Center New Orleans, is the first to report that two specific tumor suppressor genes work in concert to inhibit the growth and spread of breast tumor cells to the lungs.

12 Apr 2013

MKK4 gene could be a promising therapeutic target for liver disease, study reveals

Chronic liver failure is a major health problem that causes about one million deaths around the world each year. A study published April 11th by Cell Press in the journal Cell reveals a new type of screen for identifying genes that promote liver repair in mouse models of both acute and chronic liver disease.

12 Apr 2013

Researchers identify defective gene responsible for isolated congenital asplenia

The spleen is rarely noticed, until it is missing. In children born without this organ, that doesn't happen until they become sick with life-threatening bacterial infections.

12 Apr 2013

Weight loss surgery causes changes in DNA modifications

Gastric bypass surgery can drastically reduce the body weight of obese individuals in a short timeframe. For reasons that are not entirely clear, the surgery also leads to early remission of type 2 diabetes in the vast majority of patients.

12 Apr 2013

Study opens new avenues of research to improve care for patients with COPD

Researchers from Boston University School of Medicine have pinpointed a genetic signature for chronic obstructive pulmonary disease from airway cells harvested utilizing a minimally invasive procedure.

12 Apr 2013

Androgen receptors found to be a potential target in breast cancer

Estrogen and progesterone receptors, and the gene HER2 - these are the big three markers and/or targets in breast cancer. Evidence presented at the AACR Annual Meeting 2013 adds a fourth: androgen receptors.

11 Apr 2013

New research reveals how autophagy keeps neural stem cells to replace damaged brain, nerve cells

Deep inside your brain, a legion of stem cells lies ready to turn into new brain and nerve cells whenever and wherever you need them most. While they wait, they keep themselves in a state of perpetual readiness - poised to become any type of nerve cell you might need as your cells age or get damaged.

11 Apr 2013

Study shows genetic variant reduces pain severity associated with sexual assault

One in five U.S. women are sexually assaulted in their lifetimes and more than half experience severe pain during the week following an attack.

11 Apr 2013

Gene News and Research

Latest Gene News and Research

Researchers identify gene mutations responsible for subtype of childhood brain tumor

Researchers study gene that contributes to late-onset Alzheimer's disease in African-Americans

Johns Hopkins researchers to highlight progress in genetic research at international meeting

Death of heart tissue could be prevented with new medicines, say TUSM scientists

Scientists use mouse model to identify novel cell surface marker on mammary gland stem cells

Novel nanoparticle-based approach enables more efficient delivery of siRNA drugs

Study reveals inner workings of master regulator that controls diverse functions

Study shows more women develop chronic low back pain, sciatica than men

Researchers identify new potential therapeutic target for lowering cholesterol

Sanofi launches large-scale production of artemisinin for malaria

ATSP-9172 exhibits on-target binding activity in human prostate cancer model

Antipsychotics seemed to normalize gene expression pattern in people with bipolar disorder: Study

Researchers identify two specific tumor suppressor genes associated with breast cancer

MKK4 gene could be a promising therapeutic target for liver disease, study reveals

Researchers identify defective gene responsible for isolated congenital asplenia

Weight loss surgery causes changes in DNA modifications

Study opens new avenues of research to improve care for patients with COPD

Androgen receptors found to be a potential target in breast cancer

New research reveals how autophagy keeps neural stem cells to replace damaged brain, nerve cells

Study shows genetic variant reduces pain severity associated with sexual assault

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