Gene News and Research

Latest Gene News and Research

Researchers identify molecular signals that impact male fertility: Research

Male infertility is a common medical problem, affecting millions of men in the United States annually. Its causes include an inability to make productive sperm. Now, using yeast as a model organism, researchers at the University of Pennsylvania School of Medicine are beginning to identify the molecular signals that could in part underlie that problem.

25 Aug 2010

Also in Global Health News: IDUs in Kenya; Haiti recovery; Pandemic preparedness; Somalia hunger; HIV in Mozambique; Strengthening immune system against HIV

In Kenya, "[i]ntravenous drug users (IDUs) have been largely ignored by the government's HIV programmes on the basis that drug-taking is illegal, but a new policy is being drafted with the aim of reducing HIV transmission among this high-risk group," IRIN/PlusNews reports. The article includes comments from Nicholas Muraguri, head of the National AIDS and Sexually Transmitted Infections Control Programme, who said that the policy would treat drug use as a health issue, not a criminal one.

25 Aug 2010

National Fibromyalgia Association, RemedyMD partner to build fibromyalgia research registry

The National Fibromyalgia Association has partnered with RemedyMD® to provide a national database that will aggregate data from a wide variety of sources to provide a complete disease registry for fibromyalgia research. It offers new hope to sufferers since this will represent the first time that researchers have the opportunity to look at all data relevant to fibromyalgia in order to identify patterns which lead to more effective diagnosis and treatment.

24 Aug 2010

LabCorp launches IL-28B gene test for HCV infection

Laboratory Corporation of America® Holdings announced today the nationwide availability of a genetic test to detect the presence of a single polymorphism within the IL-28B gene that has been reported to help predict a person's response to certain hepatitis C virus (HCV) therapies.

24 Aug 2010

Epilepsy Therapy Project, EF announce recipients of New Therapy Grants Program

The Epilepsy Therapy Project (ETP) and the Epilepsy Foundation (EF) today announced the latest grant recipients of its New Therapy Grants Program, a unique joint venture of the non-profit epilepsy organizations, to advance promising epilepsy research in clinical development. The grant awards, totaling approximately $200,000 in funding, will support an experimental gene therapy that directly targets epileptogenic brain tissue, as well as an electrode system that has the potential to improve the efficacy of surgical therapies for certain epilepsy syndromes.

24 Aug 2010

Researchers find gene sequences of MLV in chronic fatigue syndrome patients' blood samples

Researchers have found murine leukemia viruses (MLV) related gene sequences in blood samples collected from patients diagnosed with chronic fatigue syndrome (CFS) and some healthy blood donors, according to a study published online today by the scientific journal Proceedings of the National Academy of Sciences (PNAS).

24 Aug 2010

WHO calls on countries to prevent, control spread of antibiotic resistant bacteria

Amid the growing threat of antimicrobial resistance, the WHO on Friday urged countries to take greater action to limit the spread of drug-resistant bacteria, CIDRAP News reports. "Calling such pathogens 'a growing and global public health problem,' the WHO said, 'Countries should be prepared to implement hospital infection control measures to limit the spread of multi-drug resistant strains and to reinforce national policy on prudent use of antibiotics, reducing the generation of antibiotic resistant bacteria,'" according to the news service (Roos, 8/20).

24 Aug 2010

Research finds variation in sex chromosome may cause lupus in men

Genes reside along long chains of DNA called chromosomes. UCLA researchers have found that a variation in a gene on the sex chromosome X may enhance an immune response that leads to lupus in men.

24 Aug 2010

Alpha-synuclein gene silencing effective for treating neurodegenerative disorders: Research

Alnylam Pharmaceuticals, Inc., a leading RNAi therapeutics company, and collaborators at The Parkinson's Institute and the Mayo Clinic have published new research findings in the journal Public Library of Science (PLoS). The new data show effective silencing of the alpha-synuclein gene with an RNAi therapeutic administered directly to the substantia nigra in the CNS of non-human primates.

24 Aug 2010

SEB opens new state-of-the-art laboratory operation, R&D facility

Cryo-Cell International, Inc., one of the largest and most established leaders in stem cell innovation today announced that S-Evans Biosciences, the Company's exclusive Célle menstrual stem cell technology license partner in China has opened a new state-of-the-art laboratory operation and research & development facility located in a Hi-Tech park designated to become an epicenter for stem cell and genomics R&D; cellular therapies and stem cell cryopreservation services.

23 Aug 2010

APC dysfunction prevents synapse function required for learning, memory: Study

A clue to the causes of autism and mental retardation lies in the synapse, the tiny intercellular junction that rapidly transfers information from one neuron to the next. According to neuroscientists at Tufts University School of Medicine, with students from the Sackler School of Graduate Biomedical Sciences at Tufts, a protein called APC plays a key role in synapse maturation, and APC dysfunction prevents the synapse function required for typical learning and memory.

23 Aug 2010

Castor bean genome may help prevent potential bioterrorism events

A research team co-led by scientists from the J. Craig Venter Institute (JCVI) and the Institute for Genome Sciences (IGS), University of Maryland School of Medicine, today published the sequence and analysis of the castor bean (Ricinus communis) genome in Nature Biotechnology.

23 Aug 2010

Researchers find new way to study oncogene's role in DNA repair

A key step in understanding the origins of familial breast cancer has been made by two teams of scientists at the University of California, Davis. The researchers have purified, for the first time, the protein produced by the breast cancer susceptibility gene BRCA2 and used it to study the oncogene's role in DNA repair.

23 Aug 2010

New diagnostic tool proves cost-effective in identifying rare genetic disorders

Mutations in a single gene can cause several types of developmental brain abnormalities that experts have traditionally considered different disorders. With support from the National Institutes of Health, researchers found those mutations through whole exome sequencing - a new gene scanning technology that cuts the cost and time of searching for rare mutations.

23 Aug 2010

WHO calls upon countries to be alert to antimicrobial resistance

Antimicrobial resistance (AMR) - the ability of micro-organisms to find ways to evade the action of the drugs used to cure the infections they cause - is increasingly recognised as a global public health issue which could hamper the control of many infectious diseases. Some bacteria have developed mechanisms which render them resistant to many of the antibiotics normally used for their treatment (multi-drug resistant bacteria), so pose particular difficulties, as there may be few or no alternative options for therapy.

21 Aug 2010

FSH society applauds findings of facioscapulohumeral muscular dystrophy

This is what we have all been working towards and fighting for, says Daniel Paul Perez, co-founder, president and CEO of the FSH Society and a 48-year-old patient with facioscapulohumeral muscular dystrophy (FSHD), applauding the researchers whose study on yesterday's ScienceXpress, the journal Science's online advanced edition, pinpoints for the first time the exact genetic mechanism triggering FSHD, the most common muscular dystrophy.

21 Aug 2010

Cyprotex launches new in vitro toxicology service

Cyprotex PLC, the preclinical ADME Tox services company, today announces the launch of its new in vitro toxicology service, branded as Cyprotox(R). Supporting the new service is an additional 90 square metres of laboratory space at Cyprotex's Macclesfield, UK facility housing the latest technology in multi-parametric automated fluorescent imaging and cellular analysis. This gives Cyprotex's Macclesfield site the same in vitro toxicology capabilities as those of Apredica (Watertown, MA, USA), which Cyprotex acquired on 6 August 2010.

From Thermo Fisher Scientific Inc. 20 Aug 2010

Even low-level exposure to cigarette smoke affects gene function in lungs

Casual smokers may think that smoking a few cigarettes a week is "no big deal." But according to new research from physician-scientists at NewYork-Presbyterian Hospital/Weill Cornell Medical Center, having an infrequent smoke, or being exposed to secondhand smoke, may be doing more harm than people may think. The findings may further support public smoking bans, say the authors.

20 Aug 2010

Bacterial pathogens require vitamin B6 biosynthesis enzymes for virulence: Study

Scientists have determined that Helicobacter pylori, the bacterium that causes peptic ulcers and some forms of stomach cancer, requires the vitamin B6 to establish and maintain chronic infection, according to research published this week in the online journal mBio-. This finding, along with the identification of the enzyme the microbe requires to utilize the vitamin, could lead to the development of an entirely new class of antibiotics.

20 Aug 2010

Scientists discover genetic flaw that causes facioscapulohumeral muscular dystrophy

Nearly two decades after they identified the specific genetic flaw that causes a common type of muscular dystrophy, scientists believe they have figured out how that flaw brings about the disease. The finding by an international team of researchers settles a longstanding question about the roots of facioscapulohumeral muscular dystrophy or FSHD.

20 Aug 2010

Gene News and Research

Latest Gene News and Research

Researchers identify molecular signals that impact male fertility: Research

Also in Global Health News: IDUs in Kenya; Haiti recovery; Pandemic preparedness; Somalia hunger; HIV in Mozambique; Strengthening immune system against HIV

National Fibromyalgia Association, RemedyMD partner to build fibromyalgia research registry

LabCorp launches IL-28B gene test for HCV infection

Epilepsy Therapy Project, EF announce recipients of New Therapy Grants Program

Researchers find gene sequences of MLV in chronic fatigue syndrome patients' blood samples

WHO calls on countries to prevent, control spread of antibiotic resistant bacteria

Research finds variation in sex chromosome may cause lupus in men

Alpha-synuclein gene silencing effective for treating neurodegenerative disorders: Research

SEB opens new state-of-the-art laboratory operation, R&D facility

APC dysfunction prevents synapse function required for learning, memory: Study

Castor bean genome may help prevent potential bioterrorism events

Researchers find new way to study oncogene's role in DNA repair

New diagnostic tool proves cost-effective in identifying rare genetic disorders

WHO calls upon countries to be alert to antimicrobial resistance

FSH society applauds findings of facioscapulohumeral muscular dystrophy

Cyprotex launches new in vitro toxicology service

Even low-level exposure to cigarette smoke affects gene function in lungs

Bacterial pathogens require vitamin B6 biosynthesis enzymes for virulence: Study

Scientists discover genetic flaw that causes facioscapulohumeral muscular dystrophy

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech