Gene News and Research

Latest Gene News and Research

Study: Pseudokinases can play a crucial role in pathogen-based disease

Researchers from the University of Pittsburgh and Stanford University discovered that a supposedly inactive protein actually plays a crucial role in the ability of one the world's most prolific pathogens to cause disease, findings that suggest the possible role of similarly errant proteins in other diseases.

1 Apr 2011

SHM honors Cogent Healthcare executives with Masters in Hospital Medicine designation

Cogent Healthcare, a leader in hospital and critical care medicine, is pleased to recognize Chief Medical Officer and Co-Founder Ron Greeno, MD, FCCP, MHM, and Chief Clinical Officer Rusty Holman, MD, MHM, for being awarded the distinction of Masters in Hospital Medicine by the Society of Hospital Medicine.

1 Apr 2011

VBL's VB-111 preclinical data against metastatic cancer to be presented at AACR meeting

VBL Therapeutics, a clinical-stage biotechnology company committed to the development of novel treatments for immune-inflammatory diseases and cancer, today announced two upcoming presentations of preclinical data from the company's VB-111 program at the American Association for Cancer Research 102nd Annual Meeting.

1 Apr 2011

Merck's VICTRELIS phase III study results against HCV presented at EASL annual meeting

Merck, known as MSD outside of the United States and Canada, announced results from several new data analyses from the pivotal Phase III studies evaluating the addition of its investigational oral protease inhibitor VICTRELIS to peginterferon alfa-2b and ribavirin in adult patients with chronic hepatitis C virus genotype 1 infection.

1 Apr 2011

DNA damage can lead to regulation of inflammatory responses

Researchers offer the first evidence that DNA damage can lead to the regulation of inflammatory responses, the body's reaction to injury. The proteins involved in the regulation help protect the body from infection.

1 Apr 2011

Alnylam completes patient enrollment in ALN-VSP Phase I trial against liver cancer

Alnylam Pharmaceuticals, Inc., a leading RNAi therapeutics company, today announced that it has completed enrollment in its ALN-VSP Phase I multi-center, multinational, open label, dose escalation clinical trial.

1 Apr 2011

Immune therapy can control fertility in mammals

Researchers at Weill Cornell Medical College have shown that it is possible to immunize mammals to control fertility. They say their technique could possibly be used on other mammals -- including humans -- because fertility hormones and their receptors are species-non-specific and are similar in both females and males. For pets, the technique could be an alternative to castration and adverse effects of hormone administration.

31 Mar 2011

Asuragen launches new miRNA Biofluids service offering

Asuragen, Inc. announced today the launch of its new miRNA Biofluids service offering designed to interrogate miRNAs from serum, plasma, cerebral spinal fluid, and urine. Supported by a growing body of literature, the utility of miRNA biomarkers in biofluids has been demonstrated for numerous disease areas including Cancer, Neurology, Autoimmune, and Cardiovascular diseases.

31 Mar 2011

Clontech launches new SMARTer Ultra Low RNA Kit

Clontech Laboratories, Inc., a wholly-owned subsidiary of Takara Bio Inc., today announced the launch of its SMARTer Ultra Low RNA Kit for Illumina Sequencing, which was developed in collaboration with Illumina, Inc.

31 Mar 2011

Insight into bowel cancer

Stem cells in the intestine, which when they mutate can lead to bowel cancers, might also be grown into transplant tissues to combat the effects of those same cancers, the UK National Stem Cell Network annual science meeting will hear today.

31 Mar 2011

Researchers suggest link between dopamine-related genes and person's risk of addiction

There is growing evidence that the risk factors for addiction change throughout the lifespan. The risk factors for developing addiction in adolescence are the most intensively studied because this life phase is associated with the highest addiction risk.

31 Mar 2011

Texas Children's Hospital and Baylor College of Medicine create Texas Children's Center for Global Health

Texas Children's Hospital and Baylor College of Medicine (BCM) today announced the creation of the Texas Children's Center for Global Health and the appointment of renowned physician-scientist Dr. Russell E. Ware as director.

31 Mar 2011

Basic Yellow 1 dye extends lifespan in healthy nematodes, slows Alzheimer's disease-like pathology in worms

Basic Yellow 1, a dye used in neuroscience laboratories around the world to detect damaged protein in Alzheimer's disease, is a wonder drug for nematode worms. In a study appearing in the March 30, online edition of Nature, the dye, also known as Thioflavin T, (ThT) extended lifespan in healthy nematode worms by more than 50 percent and slowed the disease process in worms bred to mimic aspects of Alzheimer's.

31 Mar 2011

Master regulators of cholesterol and fat play key role in liver fibrosis development

UCLA researchers have demonstrated that a key regulator of cholesterol and fat metabolism in the liver also plays an important role in the development of liver fibrosis - the build-up of collagen scar tissue that can develop into cirrhosis. Cirrhosis, in turn, is a major cause of premature death and is incurable without a liver transplant.

31 Mar 2011

Amgen appeals EMA CHMP negative opinion on Vectibix-chemotherapy combination for wild-type KRAS mCRC

Amgen announced today that it has submitted a request to the European Medicines Agency (EMA) for a re-examination of the negative opinion issued in March by the Committee For Medicinal Products for Human Use (CHMP) for the use of Vectibix in combination with chemotherapy for patients with wild-type KRAS metastatic colorectal cancer (mCRC).

31 Mar 2011

20-year data shows bariatric surgery to reduce risk of heart attack and stroke in diabetics

In the longest study of its kind, bariatric surgery has been shown to reduce the risk of heart attack and stroke in patients with diabetes. These results and other groundbreaking research were presented at the 2nd World Congress on Interventional Therapies for Type 2 Diabetes, hosted by NewYork-Presbyterian Hospital and Weill Cornell Medical College.

31 Mar 2011

Amyloid plaques in normal older individuals may be early signs of Alzheimer's

Researchers using two brain-imaging technologies have found that apparently normal older individuals with brain deposits of amyloid beta - the primary constituent of the plaques found in the brains of Alzheimer's disease patients - also had changes in brain structure similar to those seen in Alzheimer's patients.

31 Mar 2011

Regulus obtains exclusive rights from NYU for miR-33a, 33b to treat metabolic diseases

Regulus Therapeutics Inc., a biopharmaceutical company leading the discovery and development of innovative new medicines targeting microRNAs, today announced that it has obtained exclusive rights from New York University for intellectual property covering methods of use in modulating microRNA-33a and microRNA-33b for metabolic diseases such as atherosclerosis and metabolic syndrome.

31 Mar 2011

Study provides insight into kidney cancer

Researchers at UT Southwestern Medical Center have discovered genetic pathways to starve selectively kidney cancer cells.

31 Mar 2011

Gilead and Yale enter multi-year cancer research collaboration

Gilead Sciences, Inc. and Yale School of Medicine today announced the formation of a multi-year research collaboration focused on the discovery of novel cancer therapies. The research effort will initially span four years with an option to renew for up to ten years.

30 Mar 2011

Gene News and Research

Latest Gene News and Research

Study: Pseudokinases can play a crucial role in pathogen-based disease

SHM honors Cogent Healthcare executives with Masters in Hospital Medicine designation

VBL's VB-111 preclinical data against metastatic cancer to be presented at AACR meeting

Merck's VICTRELIS phase III study results against HCV presented at EASL annual meeting

DNA damage can lead to regulation of inflammatory responses

Alnylam completes patient enrollment in ALN-VSP Phase I trial against liver cancer

Immune therapy can control fertility in mammals

Asuragen launches new miRNA Biofluids service offering

Clontech launches new SMARTer Ultra Low RNA Kit

Insight into bowel cancer

Researchers suggest link between dopamine-related genes and person's risk of addiction

Texas Children's Hospital and Baylor College of Medicine create Texas Children's Center for Global Health

Basic Yellow 1 dye extends lifespan in healthy nematodes, slows Alzheimer's disease-like pathology in worms

Master regulators of cholesterol and fat play key role in liver fibrosis development

Amgen appeals EMA CHMP negative opinion on Vectibix-chemotherapy combination for wild-type KRAS mCRC

20-year data shows bariatric surgery to reduce risk of heart attack and stroke in diabetics

Amyloid plaques in normal older individuals may be early signs of Alzheimer's

Regulus obtains exclusive rights from NYU for miR-33a, 33b to treat metabolic diseases

Study provides insight into kidney cancer

Gilead and Yale enter multi-year cancer research collaboration

eBook: Using iPSCs models for human disease research and drug discovery eBook

Modular, Scalable, Intelligent: How n6 Is Rethinking NGS Library Prep

Evolving spectrophotometry for modern biopharma workflows

Scaling B-cell cloning workflows for antibody development