Gene News and Research

Latest Gene News and Research

Myotec, Hybrid merge to form PsiOxus Therapeutics

Myotec Therapeutics, Ltd. and Hybrid BioSystems, Ltd. today announced their merger to form PsiOxus Therapeutics, Ltd. (PsiOxus), a new, development stage biotechnology company using non-traditional approaches to novel therapeutics for cancer and wasting diseases. PsiOxus, which will be led by CEO Dr. John Beadle, boasts a combined pipeline of phase I and II clinical stage assets.

15 Dec 2010

Tumor suppressor p53 may serve as 'Guardian against Genome Reprogramming'

A close collaboration between researchers at the Salk Institute for Biological Studies and the Institute for Advanced Study found that the tumor suppressor p53, long thought of as the "Guardian of the Genome," may do more than thwart cancer-causing mutations. It may also prevent established cancer cells from sliding toward a more aggressive, stem-like state by serving as a "Guardian against Genome Reprogramming."

15 Dec 2010

FP/TMEM127 gene germline mutations associated with adrenal gland tumors

Analysis has identified variations of a gene that are associated with a type of tumor that forms within the adrenal gland, according a study in the December 15 issue of JAMA. The age group in which these variations were found are frequently excluded from genetic screening models for this type of tumor.

15 Dec 2010

Over expression of transcription factor improves neurological function in HD transgenic mice models

Over expressing a transcription factor that promotes the increase in number of mitochondria greatly improves the neurological function of transgenic mice models for Huntington's disease, researchers today told the American Society of Cell Biology's 50th Annual Meeting in Philadelphia.

15 Dec 2010

Genes predict survival time, potential new treatments for patients with non-small cell lung cancer

Researchers at UT Southwestern Medical Center have discovered sets of genes active in cancer cells and normal tissue that predict survival time and potential new treatments for patients with non-small cell lung cancer.

15 Dec 2010

BUSM awarded NCI EDRN, DOD grants to develop novel procedures for early detection of lung cancer

Researchers from Boston University School of Medicine (BUSM) have been awarded a five-year, $2 million grant from the National Cancer Institute (NCI) Early Detection Research Network (EDRN), as well as a four-year, $1.3 million grant from the Department of Defense (DOD). These grants will allow the scientists to develop novel and complementary procedures for early detection of lung cancer in high-risk patients.

15 Dec 2010

Clinical trial investigates pomalidomide in only U.S. study for multiple myeloma

Multiple myeloma, a type of blood cancer in which malignant plasma cells are overproduced in the bone marrow, has led to an estimated 20,000 new diagnoses and 11,000 deaths in 2010. Patients with the disease, who have already failed previous treatments, may be considered for a currently enrolling Phase II study, examining a unique drug combination.

14 Dec 2010

Lexicon reports top-line results from LX2931 Phase 2a study in rheumatoid arthritis

Lexicon Pharmaceuticals, Inc., a biopharmaceutical company focused on discovering breakthrough treatments for human disease, announced top-line results from a recently completed Phase 2a study of LX2931 in patients with rheumatoid arthritis (RA). LX2931 is an orally-delivered, small molecule drug candidate that inhibits sphingosine-1-phosphate (S1P) lyase, an enzyme important for modulating the immune system by controlling S1P levels in lymphoid tissues.

14 Dec 2010

Response Genetics presents two gene expression analysis for personalized cancer tharapy selection

Response Genetics Inc., a company focused on the development and sale of molecular diagnostic tests for cancer, announced the results of two separate analyses at national medical conferences.

14 Dec 2010

Scientists perform metagenomic analysis of bacterial immune system for personalized oral health care

The human body is home to a complex ecosystem of microbes increasingly recognized as having a critical role in both health and disease.

14 Dec 2010

Genomic Health announces results of Oncotype DX test in early-stage breast cancer patients

"We provide optimal care to breast cancer patients when we treat the underlying biology of their individual tumors," said Steven Shak, MD, chief medical officer of Genomic Health.

14 Dec 2010

Beta-catenin protein plays a key role in development of stem cells in acute leukaemia

Researchers at King's College London have discovered that leukaemic stem cells can be reversed to a pre-leukaemic stage by suppressing a protein called beta-catenin found in the blood.

14 Dec 2010

Study finds expression of toxic RNA that leads to Fragile X Tremor Ataxia Syndrome modifiable

Expression of a toxic RNA that leads to Fragile X Tremor Ataxia Syndrome is modifiable by genetic or pharmacologic means, according to new research from U-M Medical School scientists.

14 Dec 2010

Novel labeling technique helps researchers to explore DNA chemical modification

Researchers at Emory University School of Medicine and the University of Chicago have developed a method for labeling and mapping a "sixth nucleotide," whose biological role scientists are only beginning to explore.

14 Dec 2010

FOXA1 gene controls oestrogen-fuelled growth of breast cancer cells

CANCER RESEARCH UK scientists have discovered that a single gene controls the oestrogen-fuelled growth of breast cancer cells, according to research published in Nature Genetics on Sunday.

14 Dec 2010

Elsevier announces special Issue on Fetal Alcohol Spectrum Disorders

Elsevier Inc., the world's leading publisher of scientific, technical and medical information, announced today that Alcohol has published a special year-end double issue on Fetal Alcohol Spectrum Disorders (FASD). It fills an urgent need to bring the widest possible readership current perspectives on using new research methods to improve identification and diagnosis of offspring at risk for FASD and its associated brain damage and behavioral dysfunction.

13 Dec 2010

Depression in mothers during pregnancy associated with higher levels of stress hormones in children

The cocktail of hormones cascading through depressed mothers' bodies may play an important role in the development of their unborn children's brains.

13 Dec 2010

Enzo Biochem first quarter total revenues increase 2% to $25.7 million

Enzo Biochem, Inc. today reported improved sequential results for the first fiscal quarter ended October 31, 2010, the result of recent programs to reduce expenses, consolidate activities and expand operations.

13 Dec 2010

Origin of Haiti cholera epidemic traced to South Asia

The strain of cholera currently sweeping through post-earthquake Haiti originated in South Asia, conclude scientists who did a rapid genetic analysis of bacteria collected from Haitian patients. The finding supports the notion that the cholera bacteria fueling the outbreak arrived on the island via recent visitors.

13 Dec 2010

Scientists demonstrate triple-drug cocktail for triple negative breast cancer at AACR symposium

A gene target for drug resistance, a triple-drug cocktail for triple negative breast cancer, and patients' risk for carpal tunnel syndrome are among study highlights scheduled to be presented by Johns Hopkins Kimmel Cancer Center scientists during the 33rd Annual CTRC-AACR San Antonio Breast Cancer Symposium, held Dec. 8-12.

13 Dec 2010

Gene News and Research

Latest Gene News and Research

Myotec, Hybrid merge to form PsiOxus Therapeutics

Tumor suppressor p53 may serve as 'Guardian against Genome Reprogramming'

FP/TMEM127 gene germline mutations associated with adrenal gland tumors

Over expression of transcription factor improves neurological function in HD transgenic mice models

Genes predict survival time, potential new treatments for patients with non-small cell lung cancer

BUSM awarded NCI EDRN, DOD grants to develop novel procedures for early detection of lung cancer

Clinical trial investigates pomalidomide in only U.S. study for multiple myeloma

Lexicon reports top-line results from LX2931 Phase 2a study in rheumatoid arthritis

Response Genetics presents two gene expression analysis for personalized cancer tharapy selection

Scientists perform metagenomic analysis of bacterial immune system for personalized oral health care

Genomic Health announces results of Oncotype DX test in early-stage breast cancer patients

Beta-catenin protein plays a key role in development of stem cells in acute leukaemia

Study finds expression of toxic RNA that leads to Fragile X Tremor Ataxia Syndrome modifiable

Novel labeling technique helps researchers to explore DNA chemical modification

FOXA1 gene controls oestrogen-fuelled growth of breast cancer cells

Elsevier announces special Issue on Fetal Alcohol Spectrum Disorders

Depression in mothers during pregnancy associated with higher levels of stress hormones in children

Enzo Biochem first quarter total revenues increase 2% to $25.7 million

Origin of Haiti cholera epidemic traced to South Asia

Scientists demonstrate triple-drug cocktail for triple negative breast cancer at AACR symposium

eBook: Using iPSCs models for human disease research and drug discovery eBook

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting