Gene News and Research

Latest Gene News and Research

Discovery of gene expression pathway that influences process of oxidative stress

The same chemical reaction that causes iron to rust plays a similarly corrosive role in our bodies.

21 Feb 2008

Mutation in TDP-43 gene may play role in common dementia

Scientists at Washington University School of Medicine in St. Louis have linked a mutation in a gene known as TDP-43 to an inherited form of amyotrophic lateral sclerosis (ALS), the neurodegenerative condition often called Lou Gehrig's disease.

21 Feb 2008

Single microRNA plays role in innate immune response

Over the last few years scientists have discovered hundreds of microRNAs - tiny RNAs that regulate the expression of protein-coding genes.

20 Feb 2008

Scientists shed light on long-distance signaling in developing neurons

A longstanding puzzle in neurodevelopment may have yielded up a key secret.

20 Feb 2008

Researchers examine animal antibiotic resistance, possible human link

It's bad enough when pathogenic bacteria work their way into the animal food supply.

20 Feb 2008

Gene therapy - immune system discovery may lead to effective treatment for glioblastoma multiforme

A new gene therapy approach that attracts and "trains" immune system cells to destroy deadly brain cancer cells also provides long-term immunity, produces no significant adverse effects and -- in the process of destroying the tumor -- promotes the return of normal brain function and behavioral skills, according to a study conducted by researchers at Cedars-Sinai Medical Center's Board of Governors Gene Therapeutics Research Institute.

20 Feb 2008

New key finding in neurodevelopment

A longstanding puzzle in neurodevelopment may have yielded up a key secret. A team led by scientists at Weill Cornell Medical College says they have determined how events at the very tips of the developing neuron's long, skinny axon affect gene transcription back in the cell's distant nucleus.

20 Feb 2008

Tumor-targeting viral therapy slows neuroblastoma, malignant peripheral nerve sheath tumors

Researchers in a multi-institutional study led by Cincinnati Children's Hospital Medical Center slowed the growth of two particularly stubborn solid tumor cancers - neuroblastoma and peripheral nerve sheath tumors - without harming healthy tissues by inserting instructions to inhibit tissue growth into an engineered virus, according to study results published in the February 15 Cancer Research.

18 Feb 2008

Transplanted cells can cure hemophilia

Scientists at the Albert Einstein College of Medicine of Yeshiva University have shown for the first time that transplanted cells can cure hemophilia A (the most common form of the disease) in an animal model.

18 Feb 2008

Stanford researchers make first direct observation of 3-D molecule folding in real time

All the crucial proteins in our bodies must fold into complex shapes to do their jobs.

18 Feb 2008

Role gound for glaucoma gene and a signaling pathway

Researchers have found that a gene and a related signaling pathway play a role in the development of glaucoma, which is a common cause of visual impairment and blindness worldwide.

18 Feb 2008

Personalized medicine can cut breast cancer risk

The time has come for breast cancer risk assessment, counseling and genetic testing to move from cancer specialists to the realm of primary care, according to a presentation at the AAAS annual meeting, held this year in Boston.

17 Feb 2008

Cholesterol-lowering drug used to block staph infections in mince

An international team of researchers supported by the National Institutes of Health (NIH) has blocked staph infections in mice using a drug previously tested in clinical trials as a cholesterol-lowering agent.

17 Feb 2008

Discovery of new cataract gene

The international team of researchers was able to identify the location and defect in the coding region of the gene through analysis of genetic material (DNA) from members of a large Swiss family, the majority of whom suffered from autosomal dominant juvenile cataract.

17 Feb 2008

Metabolic syndrome linked to climate

Researchers from the University of Chicago have discovered that many of the genetic variations that have enabled human populations to tolerate colder climates may also affect their susceptibility to metabolic syndrome, a cluster of related abnormalities such as obesity, elevated cholesterol levels, heart disease, and diabetes.

17 Feb 2008

Major milestone in the culturing of human blood stem cells

Patients with leukemia, certain autoimmune diseases and genetic defects such as sickle-cell anemia can be treated with blood stem cells either from a donor's bone marrow or from cord blood - but the supply of effective stem cells often runs short.

17 Feb 2008

New control mechanism for genetic code translation discovered in bacteria

Almost all organisms, from bacteria to human beings, share the same genetic code, a group of universal instructions used to convert DNA or RNA sequences into proteins, the "building blocks" of life.

17 Feb 2008

Two-way cell talk provides clues about neuromuscular disease

It's a scientific given that neurons tell other cells what to do, but new evidence suggests that, like with any good relationship, these target cells also have much to contribute, scientists say.

17 Feb 2008

Exercise may reduce gallstones

A new University of Illinois study shows that exercise-trained mice get far fewer gallstones than sedentary mice and identifies potential mechanisms to explain why this occurs.

14 Feb 2008

New clues about how cancer cells grow

Scientists in Switzerland are uncovering new clues about how cancer cells grow - and how they can be killed - by studying stem cells, 'blank' cells that have the potential to develop into fully mature or 'differentiated' cells and other scientists in UK have made a breakthrough in understanding the cause of the most common form of childhood cancer, acute lymphoblastic leukaemia (ALL).

14 Feb 2008