Gene News and Research

Latest Gene News and Research

New approach to CAR T-cell therapy shows promise against small cell lung cancer in preclinical study

A new approach to chimeric antigen receptor T-cell (CAR T) therapy has shown great promise against small cell lung cancer (SCLC) in a preclinical study.

25 Apr 2023

The Wonder of DNA: Reflections from Dr. Francis Collins on the 20th Anniversary of the Human Genome Project

To highlight how far the field of genetics has come, we spoke with Dr. Francis Collins, the leader of the Human Genome Project about his incredible career in genetics.

25 Apr 2023

The potential anti-cancer and antioxidant properties of walnuts

Researchers reviewed current literature to examine walnuts' potential antioxidant and anti-cancer properties.

25 Apr 2023

Maternal and early-life exposure to high amounts of fat induce salty taste preference in offspring

We are all aware of the importance of eating healthy food, especially during pregnancy. A high-fat diet has dramatic consequences on the metabolism.

24 Apr 2023

Targeting antiviral pathway may offer a new approach to fight Alzheimer's, frontotemporal dementia

Targeting part of an antiviral pathway triggered by the accumulation of a key pathogen shared in Alzheimer's disease and frontotemporal dementia may one day offer a new therapeutic approach to deterring or delaying cognitive decline, according to preclinical research led by Weill Cornell Medicine scientists.

24 Apr 2023

New computational method identifies routes of cellular differentiation in acute myeloid leukemia

Researchers have developed a new method to distinguish between cancerous and healthy stem cells and progenitor cells from samples of patients with acute myeloid leukemia (AML), a disease driven by malignant blood stem cells that have historically been difficult to identify.

24 Apr 2023

New genome editing technology achieves efficient and precise large DNA insertions

GAO Caixia's group from the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences has developed a new genome editing technology that achieves efficient and precise targeted insertion of large DNA segments in plants.

24 Apr 2023

Mount Sinai announces creation of the Institute for Regenerative Medicine

Regenerative medicine - the process of replacing, engineering or regenerating human cells, tissues or organs - holds exciting potential for the field of health care.

24 Apr 2023

Drug-metabolizing enzyme may be a major player in safety concerns related to the painkiller diclofenac

Safety concerns related to the widely used painkiller diclofenac may be tied to a little-studied drug-metabolizing enzyme whose expression can vary as much as 3,000 times from one individual to the next, according to new research.

24 Apr 2023

Mitophagy helps blood cancer cells to evade the killing effects of BH3 mimetic drug

Despite the promise of new medications that promote cancer cell death in people with acute myeloid leukemia, leukemic cells often adopt features that let them evade the drugs' effects within a year.

24 Apr 2023

Novel cell signaling pathway could be targeted against aggressive pancreatic cancers

Researchers at the Johns Hopkins Kimmel Cancer Center identified a novel cell signaling pathway that potentially could be targeted in therapy for patients with aggressive pancreatic cancers.

24 Apr 2023

Discovery about inflammation ‘brake’ gene paves way to personalized treatments for kidney disease

A discovery about gene variants of an inflammation 'brake' brings scientists a step closer to personalised treatment for patients at risk of kidney disease and kidney failure.

24 Apr 2023

Study reveals CMPK-2 protein-coding gene as a potent inhibitor of flaviviruses

CMPK2 identified as a potential pan-flavivirus inhibitor, restricting virus replication and providing a basis for developing new antiviral treatments.

23 Apr 2023

New tool offers high accuracy in the interpretation of genetic mutations in disease genes

Despite the increasing use of genomic sequencing in clinical practice, interpreting rare genetic mutations, even among well-studied disease genes, remains difficult.

21 Apr 2023

New injectable cell therapy shows promise for treating osteoarthritis

Wake Forest Institute for Regenerative Medicine (WFIRM) scientists have created a promising injectable cell therapy to treat osteoarthritis that both reduces inflammation and also regenerates articular cartilage.

21 Apr 2023

Super-polymers are used by gut bacteria to fend off antibiotics

The discovery shows why it can be so difficult to tackle drug-resistant bacteria, but does provide a possible avenue for tackling the problem.

21 Apr 2023

Research reveals a more effective treatment for multiple sclerosis patients

Degeneration of myelin, an insulating sheath required for rapid communication between nerve cells, and neuroinflammation are notable hallmarks of Multiple Sclerosis (MS) and related neurodegenerative disorders such as Alzheimer's disease or Huntington's disease that affect roughly 2.8 million people in the world.

21 Apr 2023

Using a gene signature to predict cancer patient's response to chemotherapy agent cisplatin

Researchers at Cleveland Clinic have taken an important step in predicting which treatment will work for individual cancer patients.

21 Apr 2023

An extra gene causes excessive inhibitory connections in the neocortex of Down syndrome mouse models

An extra copy of a gene that controls synapse formation in the cortex causes excessive inhibitory signaling and may contribute to Down syndrome, according to a new study publishing April 20th in the open access journal PLOS Biology by Bing Ye of the University of Michigan, US, and colleagues.

21 Apr 2023

RExMap unlocks gut microbiome secrets: Revealing their global influence on health

Groundbreaking RExMap database enables species-level mapping of gut microbes, revealing a core set of fifteen microbes shared by humans across the globe.

21 Apr 2023

Gene News and Research

Latest Gene News and Research

New approach to CAR T-cell therapy shows promise against small cell lung cancer in preclinical study

The Wonder of DNA: Reflections from Dr. Francis Collins on the 20th Anniversary of the Human Genome Project

The potential anti-cancer and antioxidant properties of walnuts

Maternal and early-life exposure to high amounts of fat induce salty taste preference in offspring

Targeting antiviral pathway may offer a new approach to fight Alzheimer's, frontotemporal dementia

New computational method identifies routes of cellular differentiation in acute myeloid leukemia

New genome editing technology achieves efficient and precise large DNA insertions

Mount Sinai announces creation of the Institute for Regenerative Medicine

Drug-metabolizing enzyme may be a major player in safety concerns related to the painkiller diclofenac

Mitophagy helps blood cancer cells to evade the killing effects of BH3 mimetic drug

Novel cell signaling pathway could be targeted against aggressive pancreatic cancers

Discovery about inflammation ‘brake’ gene paves way to personalized treatments for kidney disease

Study reveals CMPK-2 protein-coding gene as a potent inhibitor of flaviviruses

New tool offers high accuracy in the interpretation of genetic mutations in disease genes

New injectable cell therapy shows promise for treating osteoarthritis

Super-polymers are used by gut bacteria to fend off antibiotics

Research reveals a more effective treatment for multiple sclerosis patients

Using a gene signature to predict cancer patient's response to chemotherapy agent cisplatin

An extra gene causes excessive inhibitory connections in the neocortex of Down syndrome mouse models

RExMap unlocks gut microbiome secrets: Revealing their global influence on health

eBook: Using iPSCs models for human disease research and drug discovery eBook

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting