Gene News and Research

Latest Gene News and Research

What is lactase persistence, and how did it evolve?

In this interview, we speak to Professor Mark Thomas about his latest research into lactase persistence and how it has evolved over the years.

3 May 2023

Using PandaOmics to identify dual-purpose therapeutic targets to treat aging and glioblastoma

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 8, entitled, "Identification of dual-purpose therapeutic targets implicated in aging and glioblastoma multiforme using PandaOmics - an AI-enabled biological target discovery platform."

3 May 2023

Researchers develop gene-edited stem cells to reduce arrhythmias in heart attack patients

In a recent study published in the journal Cell Stem Cell, researchers hypothesized that pacemaker-like activity of human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) resulted in engraftment arrhythmias (EAs), which hampers the clinical use of cell-based therapy using hPSC-CMs for treatment of myocardial infarction (MI).

2 May 2023

New technology can deliver gene therapy directly to the lung

Scientists at UMass Chan Medical School have developed a technology to deliver gene therapy directly to lung tissue through intranasal administration, a development that could potentially create a new class of treatments for lung disease.

2 May 2023

Drugs targeting FXR1 may treat vascular proliferative diseases

Vascular diseases, including myocardial infarction, stroke, renal failure, and peripheral vascular disease, continue to account for one third of all mortality in the United States, Europe, and the developing world (World Health Organization, 2021).

2 May 2023

Study sheds new light on the role of somatic mutations in temporal lobe epilepsy

Epilepsy affects approximately 1-in-26 people and the most common form, known as temporal lobe epilepsy (TLE), often cannot be adequately treated with anti-seizure medications.

2 May 2023

Opening doors for broader participation in oral microbiome studies: the stability and comparability of ethanol-free mouthwash

Researchers compared the use of ethanol-free and ethanol-containing mouthwash for oral microbiome studies.

1 May 2023

CRISPR-Cas9 system can help reduce adenovirus replication in human cells

The replication of potentially harmful adenoviruses can be significantly reduced in human cells in cell culture by using the so-called CRISPR-Cas9 system ("gene scissors")

29 Apr 2023

Insights into potential targets for improving diagnosis and treatment of dilated cardiomyopathy

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Dilated cardiomyopathy (DCM) is a non-ischemic heart disease that poses a substantial global health burden, but its underlying molecular mechanisms remain poorly understood.

28 Apr 2023

New approach for efficient engineering of cell and gene therapies

A new approach to the genetic engineering of cells promises significant improvements in speed, efficiency, and reduction in cellular toxicity compared to current methods.

28 Apr 2023

Cryogenic electron microscopy helps visualize structural details of gene regulation process

LMU researchers show detailed displacement process of TBP transcription factor from DNA by Mot1 enzyme.

28 Apr 2023

Heterogeneity of autism makes clinical trials difficult, says CHLA expert

Each year in the U.S. the incidence of autism spectrum disorder increases, yet the number of medications to treat the core features of autism remains stuck at zero.

28 Apr 2023

Expression profiles and roles of cardiac pigment epithelium-derived factor during cardiac development

Announcing a new article publication for Cardiovascular Innovations and Applications journal. This paper describes the expression profiles and roles of cardiac pigment epithelium-derived factor (PEDF) during cardiac development.

28 Apr 2023

A study surveilling Vermont wildlife detects no SARS-CoV-2

The surveillance of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in wildlife in Vermont, United States (US).

28 Apr 2023

Does carrot-derived rhamnogalacturonan I positively impact gut microbiota composition and function?

Researchers assessed how carrot-derived rhamnogalacturonan I (cRG-I) impacted the human gut microbiota.

28 Apr 2023

Revolutionizing drug discovery: Giga-scale screening unleashes power of AI and virtual libraries

Research discusses recent advances in computer-aided drug discovery, including the use of virtual screening and deep learning methods and their potential to revolutionize the drug discovery process by identifying diverse, potent, and drug-like ligands to protein targets.

28 Apr 2023

Alarming increases in the numbers of American children requiring special education services

In a recent publication released by PubMed, American scientists led by Dr. Dufault at the Food Ingredient and Health Research Institute, reported alarming increases in the numbers of children requiring special education services.

27 Apr 2023

New strategy for identifying small molecules offers a promising path for discovering targeted drugs

Scripps Research scientists have developed a new strategy for identifying small molecules that can change the function of proteins, offering a promising path for discovering targeted drugs.

27 Apr 2023

"Deleted" pieces of genetic information may be crucial to the development of humankind

What the human genome is lacking compared with the genomes of other primates might have been as crucial to the development of humankind as what has been added during our evolutionary history, according to a new study led by researchers at Yale and the Broad Institute of MIT and Harvard.

27 Apr 2023

3D genome mapping may lead to the treatment of deadliest pediatric brain tumors

Researchers led by Sanford Burnham Prebys assistant professor Lukas Chavez, Ph.D., are leveraging the latest technology to take a never-before-seen look at ependymoma, one of the deadliest pediatric brain tumors.

27 Apr 2023

Gene News and Research

Latest Gene News and Research

What is lactase persistence, and how did it evolve?

Using PandaOmics to identify dual-purpose therapeutic targets to treat aging and glioblastoma

Researchers develop gene-edited stem cells to reduce arrhythmias in heart attack patients

New technology can deliver gene therapy directly to the lung

Drugs targeting FXR1 may treat vascular proliferative diseases

Study sheds new light on the role of somatic mutations in temporal lobe epilepsy

Opening doors for broader participation in oral microbiome studies: the stability and comparability of ethanol-free mouthwash

CRISPR-Cas9 system can help reduce adenovirus replication in human cells

Insights into potential targets for improving diagnosis and treatment of dilated cardiomyopathy

New approach for efficient engineering of cell and gene therapies

Cryogenic electron microscopy helps visualize structural details of gene regulation process

Heterogeneity of autism makes clinical trials difficult, says CHLA expert

Expression profiles and roles of cardiac pigment epithelium-derived factor during cardiac development

A study surveilling Vermont wildlife detects no SARS-CoV-2

Does carrot-derived rhamnogalacturonan I positively impact gut microbiota composition and function?

Revolutionizing drug discovery: Giga-scale screening unleashes power of AI and virtual libraries

Alarming increases in the numbers of American children requiring special education services

New strategy for identifying small molecules offers a promising path for discovering targeted drugs

"Deleted" pieces of genetic information may be crucial to the development of humankind

3D genome mapping may lead to the treatment of deadliest pediatric brain tumors

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting