Gene News and Research

Latest Gene News and Research

Brain's glucose metabolism: Key to unlocking new therapies for Alzheimer's and Parkinson's

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20 Apr 2023

TONSL gene could be a new target for breast cancer treatment

While trying to understand what initiates breast cells to become cancerous, researchers at the Vera Bradley Foundation Center for Breast Cancer Research at Indiana University Melvin and Bren Simon Comprehensive Cancer Center have identified a new target for breast cancer treatment.

20 Apr 2023

Study links astrocytic TDP-43 dysfunction to cognitive decline in dementia: Unlocking potential therapeutic strategies

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20 Apr 2023

Newly discovered genetic variant increases risk of developing perianal Crohn's disease

Cedars-Sinai investigators have identified a genetic variant that increases people's risk of developing perianal Crohn's disease, the most debilitating manifestation of Crohn's disease.

20 Apr 2023

Gestational obesity plus zika virus infection can compromise placenta’s immune response

Researchers at the University of São Paulo (USP) in Brazil have shown for the first time that gestational obesity associated with infection by zika virus influences the placenta's antiviral response, weakening the organ's capacity to attack the pathogen and protect the fetus.

20 Apr 2023

New drug may offer relief for people with difficult-to-treat migraine

The drug atogepant may help prevent migraines for people who have had no success with other preventive drugs, according to a preliminary study released April 20, 2023, which will be presented at the American Academy of Neurology's 75th Annual Meeting being held in person in Boston and live online from April 22-27, 2023.

20 Apr 2023

Common infections in mid- and late-life can worsen cognitive performance

A new study from a team led by researchers at the Johns Hopkins Bloomberg School of Public Health found that signs of common infections in a sample of middle-aged and older adults were associated with poorer performance on a test of global cognitive function.

20 Apr 2023

Using engineered stem cells to treat ALS and retinitis pigmentosa

Cedars-Sinai investigators are developing a novel way to treat amyotrophic lateral sclerosis (ALS) and retinitis pigmentosa using engineered stem cells that may eventually lead to personalized treatments.

20 Apr 2023

Study indicates that SARS-CoV-2 has evolved to gain increased replicative fitness and become well-adapted in epithelial cells of human airways

Researchers explored increasing replicative fitness of emerging severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants

20 Apr 2023

Protein OCLN found to play crucial role in SARS-CoV-2 cell-to-cell transmission

Research explains how the SARS-CoV-2 virus spreads efficiently by directly infecting neighboring cells through a process called cell-to-cell transmission. The virus uses a protein called occludin (OCLN) to enter the cells and causes syncytium formation, which leads to viral spread.

20 Apr 2023

Simple memory test may identify people most likely to develop cognitive impairment

In people with no thinking and memory problems, a simple test may predict the risk of developing cognitive impairment years later, according to a study published in the April 19, 2023, online issue of Neurology, the medical journal of the American Academy of Neurology.

19 Apr 2023

Gene therapy approach can decrease intraocular pressure in pre-clinical models of glaucoma

Scientists at Trinity College Dublin today announced a significant development towards a new therapeutic treatment of glaucoma.

19 Apr 2023

Researchers develop novel molecular nanocages for siRNA delivery

Small interfering RNAs (siRNAs) are novel therapeutics that can be used to treat a wide range of diseases.

19 Apr 2023

Researchers compare the action of natural and therapeutic opioids

The human body naturally produces opioid-like substances, such as endorphins, which block the perception of pain and increase the feeling of well-being.

19 Apr 2023

Newly discovered protein may be pivotal for traumatic heterotopic ossification

A team led by UT Southwestern Medical Center researchers has discovered a protein that appears to be pivotal for traumatic heterotopic ossification (HO), a condition in which bone forms in muscles, tendons, and other soft tissues after traumatic injury or surgery.

19 Apr 2023

Small vesicles released by intestinal bacteria induce immune activation and progression of liver cirrhosis

Researchers from Niigata University and Kyoto Prefectural University have revealed that small vesicles, around 100 nm in size, released by intestinal bacteria induce immune activation and progression of liver cirrhosis, as well as reduction of serum albumin level, subsequently leading to edema and ascites.

19 Apr 2023

Discovery offers a potential target for TB therapies

In ongoing research aimed at developing more effective treatments for tuberculosis (TB), University of Massachusetts Amherst microbiologists have identified a long-sought gene that plays a critical role in the growth and survival of the TB pathogen.

19 Apr 2023

Study reveals DCAF1 protein's role in colon cancer development through EZH2 phosphorylation

A recent study reveals that DCAF1 is overexpressed and phosphorylates EZH2 in colon cancer cells.

18 Apr 2023

Evolution of H3 avian influenza virus in China: Implications for pandemic preparedness

This paper analyzes the evolution of the H3 subtype of avian influenza virus in China from 2009 to 2022, including its spatial and temporal distribution and genetic changes. The findings have implications for pandemic preparedness.

18 Apr 2023

Researchers discover the molecule responsible for guiding T cells toward tumors

Immunotherapy, particularly CAR T-Cell treatment for cancer, is extending the lives of many patients. But sometimes the therapy randomly migrates to places it shouldn't go, tucking into the lungs or other noncancerous tissue and causing toxic side effects.

18 Apr 2023

Gene News and Research

Latest Gene News and Research

Brain's glucose metabolism: Key to unlocking new therapies for Alzheimer's and Parkinson's

TONSL gene could be a new target for breast cancer treatment

Study links astrocytic TDP-43 dysfunction to cognitive decline in dementia: Unlocking potential therapeutic strategies

Newly discovered genetic variant increases risk of developing perianal Crohn's disease

Gestational obesity plus zika virus infection can compromise placenta’s immune response

New drug may offer relief for people with difficult-to-treat migraine

Common infections in mid- and late-life can worsen cognitive performance

Using engineered stem cells to treat ALS and retinitis pigmentosa

Study indicates that SARS-CoV-2 has evolved to gain increased replicative fitness and become well-adapted in epithelial cells of human airways

Protein OCLN found to play crucial role in SARS-CoV-2 cell-to-cell transmission

Simple memory test may identify people most likely to develop cognitive impairment

Gene therapy approach can decrease intraocular pressure in pre-clinical models of glaucoma

Researchers develop novel molecular nanocages for siRNA delivery

Researchers compare the action of natural and therapeutic opioids

Newly discovered protein may be pivotal for traumatic heterotopic ossification

Small vesicles released by intestinal bacteria induce immune activation and progression of liver cirrhosis

Discovery offers a potential target for TB therapies

Study reveals DCAF1 protein's role in colon cancer development through EZH2 phosphorylation

Evolution of H3 avian influenza virus in China: Implications for pandemic preparedness

Researchers discover the molecule responsible for guiding T cells toward tumors

eBook: Using iPSCs models for human disease research and drug discovery eBook

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting