Gene News and Research

Latest Gene News and Research

Study identifies a new detrimental effect of genes that cause inherited diseases

Scientists have identified a new detrimental effect of genes that cause inherited diseases, publishing their results today in eLife.

12 Oct 2021

Women who carry a mutation in PALB2 gene more likely to be diagnosed with breast cancer

Most of us have heard about the BRCA1 and BRCA2 genes. Men and women with a personal and/or family history of breast cancer have been offered testing for mutations in these two genes for a number of years to determine if they are at greater risk for breast and other cancers.

12 Oct 2021

Scientists develop an extremely potent siRNA with broad activity against SARS-CoVs

Researchers in Germany have developed a promising approach to suppressing the viral replication of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

12 Oct 2021

Single-genome sequencing reveals malaria parasite genetics and evolution

Understanding how malaria parasites evolve after a human is bitten by an infected mosquito is very difficult. There can be billions of individual parasites in a patient's bloodstream and traditional genetic sequencing techniques can't identify the raw material for evolution: new mutations.

12 Oct 2021

Researchers uncover how cancer cells use sugar residue to evade the immune system

A team of South Dakota State University chemistry researchers uncovered how cancer cells utilize a simple sugar residue to disguise themselves from the immune system. What they learned will help scientists develop more effective cancer therapeutics.

12 Oct 2021

Novel therapy approach could stop tumor growth

The immune system protects the body from cancer. To protect healthy body cells from its own immune system, they have developed a protective shield: the protein CD47 is a so called "don't eat me" signal, which tells the immune cells to stand back.

12 Oct 2021

Using genetic screening for selecting the 'best' embryo in IVF

Each year, tens of thousands of babies are born in the United States as the result of IVF (in vitro fertilization) – where several eggs are fertilized outside the mother's body and then an embryo is selected for transfer into her womb.

12 Oct 2021

Oxidation-antioxidant imbalance in the blood may be an early indicator of Alzheimer's disease

Research conducted by the Ph.D student Mohamed Raâfet Ben Khedher and the postdoctoral researcher Mohamed Haddad of the Institut national de la recherche scientifique has shown that an oxidation-antioxidant imbalance in the blood is an early indicator of Alzheimer's disease, rather than a consequence.

12 Oct 2021

Research reveals components of Sinbis virus ribonucleoproteins

To address this gap in research regarding the understanding of post-replicative alphavirus RNPs, scientists have created a novel proteome-wide approach known as viral RNA interactome capture (vRIC). This study is available in the bioRxiv* preprint server while awaiting peer review.

11 Oct 2021

A new bacterial two-hybrid assay to study SARS-CoV-2 interactome

Recently, scientists have developed a bacterial two-hybrid (B2H) system to study the PPIs of SARS-CoV-2 in a heterologous non-eukaryotic system. This study is available on the bioRxiv* preprint server. Put simply, the B2H system could be used to analyze the SARS-CoV-2 proteome.

11 Oct 2021

CRISPR/Cas9-directed epigenetic editing reveals diverse transcriptomic regulation and functional effects

Oncotarget published "Diverse transcriptional regulation and functional effects revealed by CRISPR/Cas9-directed epigenetic editing" which reported that the adequate functioning of this process is indispensable for tissue homeostasis and cell fate determination.

11 Oct 2021

Newly discovered molecule could be used to prevent collateral harm to vital organs during surgery

A newly detected molecule that helps reduce damage from sustained loss of blood flow to cells and tissues could eventually be used to prevent collateral harm to vital organs during surgery, according to University of Utah Health scientists.

11 Oct 2021

Drug developed at Duke is approved by FDA as only therapy for congenital athymia

The phone rang into the pediatric unit that Louise Markert, M.D., Ph.D., was staffing as a junior faculty member in 1991. Had she not answered, there would have been little hope for the more than one hundred patients who were subsequently treated.

11 Oct 2021

Penn Medicine's new Pavilion is set to open this month to staff, patients, and visitors

Referred to as a "Beacon of Hope," Penn Medicine's new Pavilion, one of the largest hospital projects underway in the United States, opens to staff, patients, and visitors this month.

11 Oct 2021

Common oral diuretic pill may be a potential candidate for Alzheimer's treatment

A commonly available oral diuretic pill approved by the U.S. Food and Drug Administration may be a potential candidate for an Alzheimer's disease treatment for those who are at genetic risk, according to findings published in Nature Aging.

11 Oct 2021

New algorithm provides a high-definition analysis of genome organization in single cells

Within the microscopic boundaries of a single human cell, the intricate folds and arrangements of protein and DNA bundles dictate a person's fate: which genes are expressed, which are suppressed, and - importantly - whether they stay healthy or develop disease.

11 Oct 2021

Plasmonic sensing of isothermally amplified nucleic acids and single-molecule detection of SARS-CoV-2

A new study finds that plasmonic sensing of LAMP amplicons through DNA hybridization enables highly specific detection of SARS-CoV-2 RNA.

11 Oct 2021

CDC and ClinGen partner to develop expert curated variant list for the genomic community

The Centers for Disease Control and Prevention's Genetic Testing Reference Material Program (GeT-RM) has partnered with the Clinical Genome Resource (ClinGen) to develop a publicly available list of 546 expert curated pathogenic variants in 84 genes for use in next-generation sequencing (NGS) genetic testing.

11 Oct 2021

Exosomal and non-exosomal miRNAs may serve as biomarkers for HCV-related cirrhosis, liver cancer

Oncotarget published "Exosomal and non-exosomal miRNA expression levels in patients with HCV-related cirrhosis and liver cancer" which reported that patients with HCV-related cirrhosis are at risk for liver cancer development.

11 Oct 2021

New metagenome assembler can generate accurate DNA sequences

Metagenomics often involves sequencing DNA samples that can only be described as "tricky." Such DNA shows high heterogeneity, which can cause interspecies misassemblies.

11 Oct 2021

Gene News and Research

Latest Gene News and Research

Study identifies a new detrimental effect of genes that cause inherited diseases

Women who carry a mutation in PALB2 gene more likely to be diagnosed with breast cancer

Scientists develop an extremely potent siRNA with broad activity against SARS-CoVs

Single-genome sequencing reveals malaria parasite genetics and evolution

Researchers uncover how cancer cells use sugar residue to evade the immune system

Novel therapy approach could stop tumor growth

Using genetic screening for selecting the 'best' embryo in IVF

Oxidation-antioxidant imbalance in the blood may be an early indicator of Alzheimer's disease

Research reveals components of Sinbis virus ribonucleoproteins

A new bacterial two-hybrid assay to study SARS-CoV-2 interactome

CRISPR/Cas9-directed epigenetic editing reveals diverse transcriptomic regulation and functional effects

Newly discovered molecule could be used to prevent collateral harm to vital organs during surgery

Drug developed at Duke is approved by FDA as only therapy for congenital athymia

Penn Medicine's new Pavilion is set to open this month to staff, patients, and visitors

Common oral diuretic pill may be a potential candidate for Alzheimer's treatment

New algorithm provides a high-definition analysis of genome organization in single cells

Plasmonic sensing of isothermally amplified nucleic acids and single-molecule detection of SARS-CoV-2

CDC and ClinGen partner to develop expert curated variant list for the genomic community

Exosomal and non-exosomal miRNAs may serve as biomarkers for HCV-related cirrhosis, liver cancer

New metagenome assembler can generate accurate DNA sequences

eBook: Using iPSCs models for human disease research and drug discovery eBook

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting