Gene News and Research

Latest Gene News and Research

Asthmatic children who are overweight or obese less likely to respond to inhaled steroids

Asthmatic children are less likely to respond to inhaled steroid medication if they are overweight or obese, and this leads to more frequent asthma attacks, according to research presented at the 'virtual' European Respiratory Society International Congress today (Wednesday).

8 Sep 2021

Researchers say modified COVID-19 vaccine boosters should control pandemic

Researchers in Texas have provided evidence for the need to modify the currently used coronavirus disease 2019 (COVID-19) vaccines to match circulating variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

8 Sep 2021

Understanding platelets in COVID-19 may help identify diagnostic markers and treatments

Researchers in the United States and Japan have provided novel insights into the pathologic mechanisms underlying coronavirus disease 2019 (COVID-19) that may aid the identification of potential diagnostic biomarkers and treatment targets.

8 Sep 2021

Understanding how pathogens evolve novel virulence activities

Understanding how pathogens evolve is a fundamental component of learning how to protect ourselves and our world from pests and diseases.

7 Sep 2021

Research reveals a previously unknown role for a key transcription regulator linked to cancer

CTCF is a transcription factor that has been a research target due to its role in regulating a critical oncogene called MYC.

7 Sep 2021

Polygenic risk score no better at predicting psychosis outcomes than written reports, study finds

With the help of cutting-edge computer programs, researchers at the Icahn School of Medicine at Mount Sinai went through the genetic and medical records of more than 8,000 schizophrenia patients.

6 Sep 2021

New insights could help unlock the mystery of how lung cancer arises in never smokers

A genomic analysis of lung cancer in people with no history of smoking has found that a majority of these tumors arise from the accumulation of mutations caused by natural processes in the body.

6 Sep 2021

Researchers develop the smallest CRISPR to date for genome editing

A compact and efficient CRISPR-Cas system, named CasMINI, could be broadly useful for cell-engineering and gene-therapy applications because it is easier to deliver into cells. The findings appear in a study publishing September 3 in the journal Molecular Cell.

4 Sep 2021

Scientists identify a critical checkpoint in transcription elongation

Northwestern Medicine scientists have identified a critical checkpoint in transcription elongation, the process of synthesizing RNA from a DNA template, according to findings published in Molecular Cell.

4 Sep 2021

Stanford researchers engineer an efficient, multi-purpose, mini CRISPR system

The common analogy for CRISPR gene editing is that it works like molecular scissors, cutting out select sections of DNA. Stanley Qi, assistant professor of bioengineering at Stanford University, likes that analogy, but he thinks it's time to reimagine CRISPR as a Swiss Army knife.

4 Sep 2021

Gut microbiome patterns provide clues to brain damage in extremely premature infants

Extremely premature infants are at a high risk for brain damage. Researchers at the University of Vienna and the Medical University of Vienna have now found possible targets for the early treatment of such damage outside the brain: Bacteria in the gut of premature infants may play a key role.

4 Sep 2021

Scientists identify novel mechanism that links genetic defect in IBD patients to gut leakiness

A team of researchers led by a biomedical scientist at the University of California, Riverside, has identified a novel mechanism by which loss-of-function mutations in the gene PTPN2, found in many patients with inflammatory bowel disease, or IBD, affect how intestinal epithelial cells maintain a barrier.

3 Sep 2021

Researchers develop a machine learning-based screening tool for genetic syndromes in children

With an average accuracy of 88%, a deep learning technology offers rapid genetic screening that could accelerate the diagnosis of genetic syndromes, recommending further investigation or referral to a specialist in seconds, according to a study published in The Lancet Digital Health.

2 Sep 2021

Distinct changes found in cancer and non-cancer immune cells in Waldenstrom macroglobulinemia

A new study by researchers at Winship Cancer Institute of Emory University finds that cancer-associated mutations originate in blood progenitor cells, leading to distinct changes in both cancer and non-cancer immune cells in Waldenstrom macroglobulinemia (WM), a type of non-Hodgkin lymphoma and its precursor IgM monoclonal gammopathy of undetermined significance (MGUS).

2 Sep 2021

CHOP researchers develop tool to monitor disease severity in patients with mitochondrial myopathy

Researchers at Children's Hospital of Philadelphia successfully developed and validated a new outcome measure to monitor disease severity and progression in patients with impaired skeletal muscle function caused by mitochondrial disease.

1 Sep 2021

Cellular protein may be a potential new target for treating osteoporosis

A cellular protein whose normal function appears to suppress bone formation may be a potential new target for treating osteoporosis, suggests a collaborative study led by Weill Cornell Medicine and NewYork-Presbyterian investigators.

1 Sep 2021

First pharmacological treatment option for patients with a severe form of epilepsy

Epilepsy comes in a variety of forms. Those affected by a genetically de- termined variety have severe epileptic seizures as early as the first year of life.

1 Sep 2021

Implanted cells deliver a biologic drug in response to inflammation in rheumatoid arthritis

With a goal of developing rheumatoid arthritis therapies with minimal side effects, researchers at Washington University School of Medicine in St. Louis have genetically engineered cells that, when implanted in mice, will deliver a biologic drug in response to inflammation.

1 Sep 2021

New model shows how dysfunction in the air sacs initiates fibrotic cascade

Idiopathic pulmonary fibrosis (IPF) is the most common and severe form of lung disease characterized by relentless scarring leading to death within an average of four years from the time of diagnosis.

31 Aug 2021

Breakthrough study could lead to much needed therapies for Huntington's disease

A new mechanism that stops the progression of Huntington's disease in cells has been identified by scientists at UCL and the University of Cambridge, as part of their research groups at the UK Dementia Research Institute.

31 Aug 2021

Gene News and Research

Latest Gene News and Research

Asthmatic children who are overweight or obese less likely to respond to inhaled steroids

Researchers say modified COVID-19 vaccine boosters should control pandemic

Understanding platelets in COVID-19 may help identify diagnostic markers and treatments

Understanding how pathogens evolve novel virulence activities

Research reveals a previously unknown role for a key transcription regulator linked to cancer

Polygenic risk score no better at predicting psychosis outcomes than written reports, study finds

New insights could help unlock the mystery of how lung cancer arises in never smokers

Researchers develop the smallest CRISPR to date for genome editing

Scientists identify a critical checkpoint in transcription elongation

Stanford researchers engineer an efficient, multi-purpose, mini CRISPR system

Gut microbiome patterns provide clues to brain damage in extremely premature infants

Scientists identify novel mechanism that links genetic defect in IBD patients to gut leakiness

Researchers develop a machine learning-based screening tool for genetic syndromes in children

Distinct changes found in cancer and non-cancer immune cells in Waldenstrom macroglobulinemia

CHOP researchers develop tool to monitor disease severity in patients with mitochondrial myopathy

Cellular protein may be a potential new target for treating osteoporosis

First pharmacological treatment option for patients with a severe form of epilepsy

Implanted cells deliver a biologic drug in response to inflammation in rheumatoid arthritis

New model shows how dysfunction in the air sacs initiates fibrotic cascade

Breakthrough study could lead to much needed therapies for Huntington's disease

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

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