Gene News and Research

Latest Gene News and Research

Severe COVID-19 characterized by phosphorylation of STAT1

A new study reports an enhanced expression of STAT1 in mild and severely infected COVID-19 patients as compared to controls

18 Aug 2021

Study shows how mesenchymal stromal cells regulate factors driving inflammation in COPD patients

A new phase I clinical study shows, for the first time, how treatment with a type of stem cell called mesenchymal stromal cells is able to regulate important factors driving inflammation in patients with chronic obstructive pulmonary disease (COPD) for a period for time.

18 Aug 2021

CRISPR screening tool pinpoints new therapeutic target to treat acute myeloid leukemia

A CRISPR screening tool identified a new therapeutic target to treat acute myeloid leukemia (AML) that has the potential to leave patients with fewer side effects than current approaches, according to a new study from Penn Medicine published online in Molecular Cell.

18 Aug 2021

New assay using fresh uncultured lung tumor cells could guide personalized treatments

A new study from the University of Helsinki shows that cells that are freshly isolated from lung cancers can be used to create robust drug response data. This approach can identify actionable or non-responsive treatments, illustrated by a case study in which the assay was used to guide the compassionate treatment of a patient.

18 Aug 2021

Study suggests Harmony COVID-19 assay is superior to laboratory-based tests

A new study suggests a new coronavirus test developed by scientists from the University of Washington and the Brotman Baty Institute for Precision Medicine produces faster and more sensitive results than conventional PCR tests to measure severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral RNA.

18 Aug 2021

SpeeDx expands product line of research reagents for SARS-CoV-2 variant analysis

SpeeDx Pty. Ltd., a developer of innovative molecular diagnostic solutions, have expanded their product line of research reagents for COVID-19 variant analysis to include a mutation connected to the SARS-CoV-2 Delta variant of concern.

18 Aug 2021

P681R spike mutation enhances replication efficiency of SARS-CoV-2 delta variant

A team of scientists from the University of Texas, USA, has recently revealed that the P681R spike mutation is responsible for increased infectivity of the delta variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The P681R spike mutation increases the replication of the delta variant by increasing the dissociation of S1 and S2 subunits at the furin cleavage site. The study is currently available on the bioRxiv* preprint server.

18 Aug 2021

Researchers receive $26.5 million NIH grant to pursue a new strategy for curing HIV

Over the last 40 years, HIV has shifted from a deadly and mysterious virus to one that can be controlled with daily drugs. But attempts to completely eliminate the virus from the bodies of people living with HIV, curing them for good, have failed.

17 Aug 2021

Weill Cornell Medicine receives $28.5 million Martin Delaney Collaboratory grant to lead HIV cure research

Weill Cornell Medicine has been awarded a five-year, $28.5 million Martin Delaney Collaboratory grant from the National Institutes of Health to lead a multi-institutional effort aimed at finding a cure for HIV.

17 Aug 2021

Infantile sudden death associated with a de novo genetic mutation in the SOS1 gene

A previously healthy infant who suffered aborted sudden cardiac death was found to have a de novo genetic mutation in the SOS1 gene.

17 Aug 2021

ERS Genomics and Cellular Engineering Technologies Enter CRISPR/Cas9 License Agreement

ERS Genomics Limited and Cellular Engineering Technologies today announced a non-exclusive license agreement.

17 Aug 2021

HORIBA to showcase novel POCKIT Central PCR analyser at BEVA and Vets North

HORIBA UK Limited will be showcasing its new benchtop POCKIT™ Central* in-house veterinary PCR analyser on Stand C3 at the BEVA Congress.

From HORIBA Medical 17 Aug 2021

Mutated enzyme impairs communication between neurons and causes motor defects in SCA34 model

In one type of a rare, inherited genetic disorder that affects control of body movement, scientists have found a mutation in an enzyme that impairs communication between neurons and what should be the inherent ability to pick up our pace when we need to run, instead of walk, across the street.

17 Aug 2021

Researchers confirm the speed, simplicity and accuracy of new COVID-19 testing method

Researchers from the University of Birmingham, U.K., have confirmed the speed, accuracy, and simplicity of a novel, a highly sensitive testing method for COVID-19 that can be deployed at entertainment venues, airport arrival terminals, and in remote settings where clinical testing laboratories are not available.

17 Aug 2021

Vaccinating previously infected induces more potent antibodies less susceptible to escape from SARS-CoV-2 variants

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is the causal agent of the coronavirus disease 2019 (COVID-19) pandemic, which has claimed more than 4.3 million lives worldwide. Even after implementing various measures, such as vaccination and social restrictions, SARS-CoV-2 and its variants of concern (VoC) leave the world's public health systems and economies in turmoil.

16 Aug 2021

Study provides insight into fitness effects of genomic structural variants in natural populations

Molecular geneticists have known for about a decade that genomic structural variants can play important roles in the adaptation and speciation of both plants and animals, but their overall influence on the fitness of plant populations is poorly understood.

16 Aug 2021

Tool for defining new SARS-CoV-2 spike nucleotide sequences to Pango lineage sets

In a recent study, a group of researchers determined the degree to which Pango lineages are distinguishable using spike-only nucleotide sequences.

16 Aug 2021

Hedgehog-signaling inhibitor may shift tumor-associated macrophages back to cancer fighters

A form of cell communication called hedgehog signaling is vital for embryonic development in mammals.

16 Aug 2021

UH researcher set to explore how testosterone works in the brain

Most people have some idea about the hormone testosterone –how it regulates male behavior or how too little of it might cause a decrease in libido and too much might cause aggressive and irritable behavior. Turns out, no one yet knows how testosterone really does all that.

16 Aug 2021

Combining inhibitor drug with immunotherapy agent improves response in cancer patients

Combining a histone deacetylase inhibitor drug with immunotherapy agents is safe, and may benefit some patients with advanced cancers that have not responded to traditional therapy, according to results of a phase 1 clinical trial led by researchers at the Johns Hopkins Kimmel Cancer Center, Bloomberg~Kimmel Institute for Cancer Immunotherapy and several other centers including University of Pittsburgh Cancer Institute, Yale Cancer Center and City of Hope in Los Angeles, which participated in study enrollment, and the University of Southern California and University College Cork in Ireland, which collaborated on analysis of the data.

16 Aug 2021

Gene News and Research

Latest Gene News and Research

Severe COVID-19 characterized by phosphorylation of STAT1

Study shows how mesenchymal stromal cells regulate factors driving inflammation in COPD patients

CRISPR screening tool pinpoints new therapeutic target to treat acute myeloid leukemia

New assay using fresh uncultured lung tumor cells could guide personalized treatments

Study suggests Harmony COVID-19 assay is superior to laboratory-based tests

SpeeDx expands product line of research reagents for SARS-CoV-2 variant analysis

P681R spike mutation enhances replication efficiency of SARS-CoV-2 delta variant

Researchers receive $26.5 million NIH grant to pursue a new strategy for curing HIV

Weill Cornell Medicine receives $28.5 million Martin Delaney Collaboratory grant to lead HIV cure research

Infantile sudden death associated with a de novo genetic mutation in the SOS1 gene

ERS Genomics and Cellular Engineering Technologies Enter CRISPR/Cas9 License Agreement

HORIBA to showcase novel POCKIT Central PCR analyser at BEVA and Vets North

Mutated enzyme impairs communication between neurons and causes motor defects in SCA34 model

Researchers confirm the speed, simplicity and accuracy of new COVID-19 testing method

Vaccinating previously infected induces more potent antibodies less susceptible to escape from SARS-CoV-2 variants

Study provides insight into fitness effects of genomic structural variants in natural populations

Tool for defining new SARS-CoV-2 spike nucleotide sequences to Pango lineage sets

Hedgehog-signaling inhibitor may shift tumor-associated macrophages back to cancer fighters

UH researcher set to explore how testosterone works in the brain

Combining inhibitor drug with immunotherapy agent improves response in cancer patients

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging