Gene News and Research

Latest Gene News and Research

Discovery suggests new approach for targeting most-wanted molecular culprits in cancer

A discovery by scientists at Dana-Farber Cancer Institute and University of Texas Southwestern Medical Center presents drug developers with an entirely new tack in targeting one of the most-wanted molecular culprits in cancer.

12 Jan 2018

Prostate cancer’s gene-determined ‘immune landscape’ dictates tumor progression

The field of immunotherapy - the harnessing of patients' own immune systems to fend off cancer - is revolutionizing cancer treatment today. However, clinical trials often show marked improvements in only small subsets of patients, suggesting that as-yet unidentified variations among tumors result in distinct paths of disease progression and response to therapy.

12 Jan 2018

Genetic analysis can enhance outcomes of depression treatment

The failure of drugs such as SSRIs, used to treat depression, can be a result of genetic variations in patients.

12 Jan 2018

Study finds new mechanism regulating giant protein essential for muscle and heart function

Scientists at the Centro Nacional de Investigaciones Cardiovasculares Carlos III and Columbia University in New York have discovered an important mechanism in the regulation of a protein that plays an essential role in the function of skeletal muscle and the heart.

12 Jan 2018

Study finds overall pattern of commonality between Huntington's and Parkinson's

A new study strongly suggests that the brains of people who have died of Huntington's disease (HD) and Parkinson's disease (PD) show a similar response to a lifetime of neurodegeneration, despite being two very distinct diseases.

12 Jan 2018

Researchers discover new type of botulinum neurotoxin from unexpected source

Researchers from the Quadram Institute have identified genes encoding a previously undiscovered version of the botulinum neurotoxin in bacteria from a cow's gut.

12 Jan 2018

Research provides insights into mechanisms governing healthy longevity

Keio University Global Research Institute, Tokyo publishes the January 2018 issue of KGRI Research Frontiers that includes researcher video profiles of Keio University researchers and research highlights from high impact publications including 'Regenerative medicine needs collaboration in and out of science in order to face current and future challenges; ‘Does eating fish protect you from depression?’; ‘Insights into the molecular mechanisms leading to kidney dysfunction in diabetic patients’; and ‘Ageing to 100 and beyond: Insights from demographic, phenotypic and genetic studies.

12 Jan 2018

BRCA gene mutation does not raise the risk of death

BRCA gene mutation has been associated with cancers such as breast cancer. The BRCA gene mutation detection had resulted in a prophylactic double mastectomy for actress Angelina Jolie anticipating cancer. Now a new study has shown that having a BRCA gene mutation and being diagnosed with breast cancer does not raise the risk of death after diagnosis. The study was published in the latest issue of the journal The Lancet Oncology.

11 Jan 2018

Mount Sinai study uncovers potential link between Crohn's and Parkinson's in Jewish population

Mount Sinai Researchers have just discovered that patients in the Ashkenazi Jewish population with Crohn's disease (a chronic inflammatory of the digestive system) are more likely to carry the LRRK2 gene mutation.

11 Jan 2018

New study shows how the immune system regulates gut fungal population

Immune cells that process food and bacterial antigens in the intestines control the intestinal population of fungi, according to a new study from Weill Cornell Medicine scientists.

11 Jan 2018

Researchers discover new promising biomarker for colorectal cancer

Researchers from the University of Luxembourg found a new biomarker for colorectal cancer (CRC) that might improve therapy and survival rates of patients.

11 Jan 2018

Study identifies enzyme that regulates inflammation and metabolism in fat tissue

The human body has two primary kinds of fat--white fat, which stores excess calories and is associated with obesity, and brown fat, which burns calories in order to produce heat and has garnered interest as a potential means of combating obesity.

11 Jan 2018

Company-sponsored CRISPR clinical studies to begin in 2018

This year could be a defining one for CRISPR, the gene editing technique, which has been hailed as an important breakthrough in laboratory research.

10 Jan 2018

Study finds genetic variations linked to BMI and obesity risk

It's not just diet and physical activity; your genes also determine how easily you lose or gain weight. In a study published in the January issue of Nature Genetics, researchers at the Icahn School of Medicine at Mount Sinai and other institutions of the Genetic Investigation of Anthropometric Traits consortium found 13 genes that carry variations associated with body mass index.

10 Jan 2018

Biomarkers may help predict prognosis of gastric cancer patients with alcohol consumption habits

Alcohol consumption has been identified as a modifiable risk factor for cancers such as gastric cancer. A new report in the The American Journal of Pathology sheds light on how specific proteins interact with alcohol, and how that interplay impacts survival and response to platinum-based adjuvant chemotherapy in patients with gastric cancer who may or may not still be drinking.

10 Jan 2018

Family study looks at potential genetic distinctions between bipolar disorder subtypes

The most common subtypes of bipolar disorder, bipolar I and bipolar II, stem-at least in part-from different biological causes, according to a new study published in Biological Psychiatry.

10 Jan 2018

New discovery could help treat breast cancer through precision medicine

University of Alberta researchers have discovered a mechanism that may make cancer cells more susceptible to treatment. The research team found that the protein RYBP prevents DNA repair in cancer cells, including breast cancer.

9 Jan 2018

UC scientists identify protein that acts as mediator of HER2-driven breast cancer

Researchers at the University of Cincinnati College of Medicine have identified for the first time that the estrogen receptor-binding protein MED1 is a critical mediator of HER2-driven breast cancer, identifying it as a potential therapeutic target.

9 Jan 2018

New blood stabilization method prolongs lifespan of blood samples for CTC profiling

A new blood stabilization method, developed at the Massachusetts General Hospital Center for Engineering in Medicine, significantly prolongs the lifespan of blood samples for microfluidic sorting and transcriptome profiling of rare circulating tumor cells (CTCs), living cancer cells carried in the bloodstream.

9 Jan 2018

Scientists find gene that predisposes Greenlanders to obesity

Greenland is like many other countries struggling with overweight and obesity. Both environment and genetics play a role in development of obesity.

9 Jan 2018

Gene News and Research

Latest Gene News and Research

Discovery suggests new approach for targeting most-wanted molecular culprits in cancer

Prostate cancer’s gene-determined ‘immune landscape’ dictates tumor progression

Genetic analysis can enhance outcomes of depression treatment

Study finds new mechanism regulating giant protein essential for muscle and heart function

Study finds overall pattern of commonality between Huntington's and Parkinson's

Researchers discover new type of botulinum neurotoxin from unexpected source

Research provides insights into mechanisms governing healthy longevity

BRCA gene mutation does not raise the risk of death

Mount Sinai study uncovers potential link between Crohn's and Parkinson's in Jewish population

New study shows how the immune system regulates gut fungal population

Researchers discover new promising biomarker for colorectal cancer

Study identifies enzyme that regulates inflammation and metabolism in fat tissue

Company-sponsored CRISPR clinical studies to begin in 2018

Study finds genetic variations linked to BMI and obesity risk

Biomarkers may help predict prognosis of gastric cancer patients with alcohol consumption habits

Family study looks at potential genetic distinctions between bipolar disorder subtypes

New discovery could help treat breast cancer through precision medicine

UC scientists identify protein that acts as mediator of HER2-driven breast cancer

New blood stabilization method prolongs lifespan of blood samples for CTC profiling

Scientists find gene that predisposes Greenlanders to obesity

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research