Gene News and Research

Latest Gene News and Research

Combining oral drug with personalized cell therapy can lead to complete remission in CLL patients

Combining the kinase inhibitor ibrutinib with an investigational personalized cellular therapy known as CTL119 can lead to complete remission in patients with high-risk chronic lymphocytic leukemia (CLL), according to new research from the Perelman School of Medicine at the University of Pennsylvania and Penn's Abramson Cancer Center

31 May 2017

TB germs' metabolic 'escape pathways' may be neutralized by new drugs to shorten duration of therapy

New research suggests the bacteria that cause tuberculosis alter their metabolism to combat exposure to antimicrobials, and that these metabolic "escape pathways" might be neutralized by new drugs to shorten the troublesome duration of therapy.

31 May 2017

Researchers make significant advance in treatment of bowel cancer

New research led by Queen's University Belfast has discovered how a genomic approach to understanding bowel (colorectal) cancer could improve the prognosis and quality of life for patients.

31 May 2017

Radboudumc, iMM Lisboa, PATH team up to test new malaria vaccine concept

The Radboud University Medical Center in the Netherlands, the Instituto de Medicina Molecular Lisboa in Portugal, and PATH in Seattle, Washington announced today that they will collaborate to test a new approach to malaria vaccine development in humans for the first time.

31 May 2017

Real-time imaging of influenza infection in mice can be promising evaluation tool

Real-time imaging of influenza infection in mice is a promising new method to quickly monitor disease progression and to evaluate whether candidate vaccines and treatments are effective in this animal model, according to National Institutes of Health scientists.

31 May 2017

GW researcher receives NIH funding to explore ways for standardization of cancer genomics data

One of the biggest challenges facing cancer genomics researchers is the lack normalized data on cancer genes. Multitudes of genomics projects have been funded over the years that have resulted in data being placed on several different databases, making a wide array of data and annotations difficult to integrate and compare.

30 May 2017

Investigational compound inhibits cancer-specific mutations in mice

Many malignancies develop as a result of genetic alterations in individual cells. These gene mutations often cause altered proteins that give new, growth-promoting properties to the cell.

30 May 2017

CRISPR may not be as foolproof as earlier believed – gene editing tech leads to unwanted mutations

CRISPR-Cas9 is a revolutionary new gene-editing technology that has been called “molecular scissors” and has been one of the handiest tools for genetic engineers in the recent times. It makes cutting and pasting gene sequences almost as easy as it sounds. CRISPR has been hailed as a breakthrough in genetic engineering.

30 May 2017

Kyoto University researchers identify specific gene as key regulator in iron uptake

Maintaining a good balance of iron in the body is necessary for health: too little can lead to anemia, but too much can cause debilitating disorders such as hemochromatosis.

30 May 2017

Scientists create a faster, less labor-intensive test to detect “hidden” HIV

The search to develop a HIV cure has long been overwhelmed by a seemingly simple question: How do physicians find out if somebody is cured? The virus has an ability to lie dormant in immune cells at levels that could not be detected to all, however, the most expensive and time-consuming tests can find the hidden virus.

30 May 2017

Researchers develop new mouse model that could lead to better treatment of kidney cancer

Research in the field of kidney cancer, also called renal cancer, is vital, because many patients with this disease still cannot be cured today.

30 May 2017

Gene editing technology can introduce hundreds of unintended mutations, study shows

As CRISPR-Cas9 starts to move into clinical trials, a new study published in Nature Methods has found that the gene-editing technology can introduce hundreds of unintended mutations into the genome.

29 May 2017

Drug treatment used for other conditions can help women combat urinary incontinence

Urinary incontinence in women is common, with almost 50% of adult women experiencing leakage at least occasionally. Genetic or heritable factors are known to contribute to half of all cases, but until now studies had failed to identify the genetic variants associated with the condition.

29 May 2017

Psychiatrist explains dangerous effects of cocaine addiction

Last year, almost a million in the UK people snorted, dabbed, smoked or injected cocaine, making it the second most popular drug in the country, after cannabis.

29 May 2017

Prolaris becomes first genetic test to receive Medicare coverage for favorable intermediate and low-risk prostate cancer

Myriad Genetics, Inc., a leader in molecular diagnostics and personalized medicine, today announced that Palmetto GBA, a Medicare Administrative Contractor that assesses molecular diagnostic technologies, has issued a positive final Local Coverage Determination to expand Medicare coverage of the Prolaris test.

29 May 2017

Dragon Master Foundation to fund DIPG trial that will make patient data available live in the cloud

Dragon Master Foundation has announced plans to provide $300,000 in funding for the first clinical trial that will make patient data available live in the cloud while the trial is underway.

27 May 2017

FDA approves expanded use of Zykadia for first-line treatment of ALK-positive metastatic NSCLC

Novartis today announced the US Food and Drug Administration approved the expanded use of Zykadia (ceritinib) to include the first-line treatment of patients with metastatic non-small cell lung cancer (NSCLC) whose tumors are anaplastic lymphoma kinase (ALK)-positive, as detected by an FDA-approved test.

27 May 2017

Open-access BRCA testing for inherited breast cancer enables identification of missed carriers

Ashkenazi Jewish women are known to have a predisposition to the inherited breast cancers BRCA1 and BRCA2, but currently genetic testing in this group is limited to women affected by breast and ovarian cancers and those who are unaffected but have a family history of the disease.

27 May 2017

UNC researchers discover cascade of gene activity during journey to maturation in fruit flies

Every animal starts as a clump of cells, which over time multiply and mature into many different types of cells, tissues, and organs.

26 May 2017

Innate genetic advantage contributes to better outcomes in newborn infant girls than boys, research shows

Newborn infant girls have better outcomes than their male counterparts due to an innate genetic advantage in responding to acute infections, according to new research from RCSI.

26 May 2017

Gene News and Research

Latest Gene News and Research

Combining oral drug with personalized cell therapy can lead to complete remission in CLL patients

TB germs' metabolic 'escape pathways' may be neutralized by new drugs to shorten duration of therapy

Researchers make significant advance in treatment of bowel cancer

Radboudumc, iMM Lisboa, PATH team up to test new malaria vaccine concept

Real-time imaging of influenza infection in mice can be promising evaluation tool

GW researcher receives NIH funding to explore ways for standardization of cancer genomics data

Investigational compound inhibits cancer-specific mutations in mice

CRISPR may not be as foolproof as earlier believed – gene editing tech leads to unwanted mutations

Kyoto University researchers identify specific gene as key regulator in iron uptake

Scientists create a faster, less labor-intensive test to detect “hidden” HIV

Researchers develop new mouse model that could lead to better treatment of kidney cancer

Gene editing technology can introduce hundreds of unintended mutations, study shows

Drug treatment used for other conditions can help women combat urinary incontinence

Psychiatrist explains dangerous effects of cocaine addiction

Prolaris becomes first genetic test to receive Medicare coverage for favorable intermediate and low-risk prostate cancer

Dragon Master Foundation to fund DIPG trial that will make patient data available live in the cloud

FDA approves expanded use of Zykadia for first-line treatment of ALK-positive metastatic NSCLC

Open-access BRCA testing for inherited breast cancer enables identification of missed carriers

UNC researchers discover cascade of gene activity during journey to maturation in fruit flies

Innate genetic advantage contributes to better outcomes in newborn infant girls than boys, research shows

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