Gene News and Research

Latest Gene News and Research

Study provides insights into biology of protein implicated in kidney disease

Investigators have discovered important information about apolipoprotein L1 (ApoL1), which can contribute to the development of various forms of kidney disease.

9 Dec 2016

Study identifies recurrent genomic alterations in subset of breast cancer

A genomic analysis study by Rutgers Cancer Institute of New Jersey investigators and other colleagues has identified recurrent genomic alterations in a subset of breast cancer that are typically associated with a form of thyroid cancer and an intestinal birth defect known as Hirschsprung disease.

9 Dec 2016

Researchers uncover first ‘off-switches’ for better control of CRISPR/Cas9 gene editing

CRISPR/Cas9 genome editing is quickly revolutionizing biomedical research, but the new technology is not yet exact. The technique can inadvertently make excessive or unwanted changes in the genome and create off-target mutations, limiting safety and efficacy in therapeutic applications.

9 Dec 2016

GWAS identifies genomic locations linked to personality traits and psychiatric disorders

A meta-analysis of genome-wide association studies has identified six loci or regions of the human genome that are significantly linked to personality traits, report researchers at University of California San Diego School of Medicine in this week's advance online publication of Nature Genetics.

9 Dec 2016

Studies show how overactive immune response may contribute to heart disease in psoriasis patients

Psoriasis is well-known for causing too many skin cells on elbows, knees, and across the body, but people living with psoriasis may also be at an increased risk of heart disease.

9 Dec 2016

Human migration study reveals new insights into cancer metastasis

What could cancer cells and drug-resistant bacteria possibly have in common with Stone Age settlers of the Americas? They're all migratory, and at one time or other, each finds the going a bit easier in a specific direction.

9 Dec 2016

Researchers crack genetic code of lung tissues to identify novel targets for treating IPF

Researchers cracked the complete genetic code of individual cells in healthy and diseased human lung tissues to find potential new molecular targets for diagnosing and treating the lethal lung disease Idiopathic Pulmonary Fibrosis (IPF).

8 Dec 2016

RNA modifications play significant role in function of nervous system

Researchers at the Institute of Molecular Biology and Johannes Gutenberg University Mainz have shown that a new way of regulating genes is vital for the activity of the nervous system.

8 Dec 2016

Duke researchers develop new cell-based drug screening test for dystonia

Duke University researchers have identified a common mechanism underlying separate forms of dystonia, a family of brain disorders that cause involuntary, debilitating and often painful movements, including twists and turns of different parts of the body.

8 Dec 2016

Scientists identify biomarkers to predict patient’s response to breast cancer treatment

Why do some breast cancers respond to treatment while others resist it? A study led by researchers at the University of North Carolina Lineberger Comprehensive Cancer Center may provide insight into this important question.

8 Dec 2016

Scientists discover truncated p53 proteins that promote cancer growth and metastasis

Discovered in the 1970s, tumor suppressors are among the most important proteins in the body.

8 Dec 2016

Scientists use unified analysis approach for diagnosing diseases with multiple genetic causes

Scientists at Baylor College of Medicine, Baylor Genetics, the University of Texas Health Science Center at Houston and Texas Children's Hospital are combining descriptions of patients' clinical features with their complex genetic information in a unified analysis to obtain more precise diagnoses of complex diseases, particularly those that involve more than one gene causing the condition.

8 Dec 2016

Honeybee brain helps unravel mystery behind long-term memory formation

A breakdown of memory processes in humans can lead to conditions such as Alzheimer's and dementia.

8 Dec 2016

Research reveals opposing role for SNAP23 protein in endocrine and exocrine pancreas

Movement of secretory molecules, such as hormones and digestive enzymes, out of the cell is known as exocytosis. This process is guided by SNARE proteins, which help the fusion of secretory vesicles with the plasma membrane.

8 Dec 2016

Neurons generated at different life stages can impact olfactory behavior in mice, research shows

New research from North Carolina State University shows that neurons generated at different life stages in mice can impact aspects of their olfactory sense and behavior.

8 Dec 2016

Synthetic sgRNA for CRISPR genome editing

Chemically synthesized single guide RNA is the best way to do CRISPR genome editing. It is more pure than biological methods of creating guide RNAs, like in vitro transcription or plasmids. As a result, sgRNA leads to more consistency and higher quality.

8 Dec 2016

Gene News and Research

Latest Gene News and Research

Study provides insights into biology of protein implicated in kidney disease

Study identifies recurrent genomic alterations in subset of breast cancer

Researchers uncover first ‘off-switches’ for better control of CRISPR/Cas9 gene editing

GWAS identifies genomic locations linked to personality traits and psychiatric disorders

Studies show how overactive immune response may contribute to heart disease in psoriasis patients

Human migration study reveals new insights into cancer metastasis

Researchers crack genetic code of lung tissues to identify novel targets for treating IPF

RNA modifications play significant role in function of nervous system

Duke researchers develop new cell-based drug screening test for dystonia

Scientists identify biomarkers to predict patient’s response to breast cancer treatment

Scientists discover truncated p53 proteins that promote cancer growth and metastasis

Scientists use unified analysis approach for diagnosing diseases with multiple genetic causes

Honeybee brain helps unravel mystery behind long-term memory formation

Research reveals opposing role for SNAP23 protein in endocrine and exocrine pancreas

Neurons generated at different life stages can impact olfactory behavior in mice, research shows

Synthetic sgRNA for CRISPR genome editing

Stem cell-based risk scoring tool could predict AML patient’s response to standard treatment

Researchers developing model to predict breast cancer patient’s response to chemotherapy

Dental problems linked to cleft lip and palate may be caused by abnormal salivary glands

Pathogenic variants in certain genes increase woman's likelihood of developing breast cancer

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How cohesin mechanics and nanotracker tech are redefining DNA research