Gene News and Research

Latest Gene News and Research

Improper methylation of cilia protein linked to increased risk of neural tube defects

Research published online in The FASEB Journal shows that the improper methylation of a protein called "Septin2," which regulates the structure of cilia, was associated with an increased risk of having a neural tube defect (NTD) and confirms that cilia are important factors in determining susceptibility of NTDs.

11 May 2017

Researchers identify microRNA biomarker linked to incidence of atrial fibrillation

Researchers have identified a microRNA biomarker that demonstrates a strong association with the incidence of atrial fibrillation, the most common abnormal heart rhythm that affects more than 2.7 million Americans.

11 May 2017

Research lays groundwork to develop realistic ‘biomimetic neuroprosthetics’

By applying a novel computer algorithm to mimic how the brain learns, a team of researchers – with the aid of the Comet supercomputer based at the San Diego Supercomputer Center at UC San Diego and the Center's Neuroscience Gateway – has identified and replicated neural circuitry that resembles the way an unimpaired brain controls limb movement.

11 May 2017

Chemical stimuli by small molecule can improve production of cartilage cells

Cell-based therapies could offer a way to treat cartilage injuries before the ultimate damage of osteoarthritis on articular cartilage.

11 May 2017

Breast cancer drug offers protection against obesity-related metabolic disorders

Tamoxifen, a selective estrogen receptor modulator, is the gold standard for endocrine treatment of estrogen-receptor positive breast cancer.

11 May 2017

Scientists identify unusual mutations in endometriosis using gene sequencing tools

Using gene sequencing tools, scientists from Johns Hopkins Medicine and the University of British Columbia have found a set of genetic mutations in samples from 24 women with benign endometriosis, a painful disorder marked by the growth of uterine tissue outside of the womb.

11 May 2017

Sangamo Therapeutics and Pfizer team up for development of Hemophilia A gene therapy

Sangamo Therapeutics, Inc. and Pfizer Inc. today announced an exclusive, global collaboration and license agreement for the development and commercialization of gene therapy programs for Hemophilia A, including SB-525, one of Sangamo's four lead product candidates, which Sangamo expects will enter the clinic this quarter.

11 May 2017

Study generates comprehensive catalog of diseases linked to variations in HLA genes

A study led by researchers at Vanderbilt University Medical Center and the University of Arizona College of Pharmacy has generated the first comprehensive catalog of diseases associated with variations in human leukocyte antigen genes that regulate the body's immune system.

11 May 2017

Early-onset pancreatitis in children linked to family history and genetic mutations

A study published today in The Journal of Pediatrics suggests that early-onset pancreatitis in children is strongly associated with certain genetic mutations and family history of pancreatitis.

10 May 2017

UT Health scientists discover epigenetic changes that contribute to AML

UT Health San Antonio researchers discovered epigenetic changes that contribute to one-fifth of cases of acute myeloid leukemia (AML), an aggressive cancer that arises out of the blood-forming cells in bone marrow.

10 May 2017

Gut microbiome may play key role in pathology of common cerebrovascular disease

Bacteria in the gut microbiome drive the formation of cerebral cavernous malformations (CCMs), clusters of dilated, thin-walled blood vessels in the brain that can cause stroke and seizures, according to new research published this week in Nature by researchers from the Perelman School of Medicine at the University of Pennsylvania.

10 May 2017

UC researchers find stem cell vaccine to enhance immune responses against tumors in animal models

Researchers at the University of Cincinnati have found that a cancer stem cell vaccine, engineered to express a pro-inflammatory protein called interleukin-15 (IL-15) and its receptor (IL-15Ralpha), caused T cell production in animal models and enhanced immune responses against tumors.

10 May 2017

New findings pinpoint key feature of rare childhood disease that could help fast-track diagnosis

Australian scientists have shown, for the first time, that a family of untethered proteins builds up in the cells of children with a rare and serious genetic condition, known as mevalonate kinase deficiency (MKD).

10 May 2017

Serum Institute signs licensing agreement to commercialize St. Jude vaccine against RSV

St. Jude Children's Research Hospital and the Serum Institute of India have signed a licensing agreement to complete development and commercialization of a St. Jude vaccine against the respiratory syncytial virus (RSV), the virus that causes croup and lower respiratory infections. RSV kills about 160,000 people, primarily infants, worldwide each year.

10 May 2017

Children's bone health could be determined before birth, study shows

The health of children's bones could be determined before they are born, a new University of Southampton study has shown.

10 May 2017

Researchers uncover structure of embryo-protecting protein

Revelations about a protein expressed in fetal cells could provide novel insights into its function and future immunosuppressive therapies.

10 May 2017

Studies pave way for genome-targeted treatments in pancreatic cancer

University of Pittsburgh and UPMC researchers are paving the way for genome-targeted treatments in pancreatic cancer, an especially deadly form of cancer with few existing therapeutic options, according to a pair of recent studies.

9 May 2017

Study findings could help identify treatments for balding and hair graying

Researchers at the UT Southwestern Medical Center have discovered the cells that are directly responsible for hair growth and the mechanism that causes gray hair. The study results could help in identifying feasible treatments for balding and hair graying.

9 May 2017

BGRF scientists help develop AI to expedite drug development for age-related conditions

The Chief Science Officer of the Biogerontology Research Foundation will present new research on artificial intelligence for drug discovery at the NVIDIA Graphics Technology Conference at the San Jose Convention Center, on Wednesday, May 10, 1:00 PM - 1:50 PM alongside two AI scientists from the BGRF and Insilico Medicine, where they will deliver a presentation titled "Applications of Generative Adversarial Networks to Drug Discovery in Oncology and Infectious Diseases".

9 May 2017

UVA research finding sheds light on cause of deadly heart condition

Kidney research at the University of Virginia School of Medicine has unexpectedly led to a discovery about the formation of the heart, including the identification of a gene responsible for a deadly cardiac condition.

9 May 2017

Gene News and Research

Latest Gene News and Research

Improper methylation of cilia protein linked to increased risk of neural tube defects

Researchers identify microRNA biomarker linked to incidence of atrial fibrillation

Research lays groundwork to develop realistic ‘biomimetic neuroprosthetics’

Chemical stimuli by small molecule can improve production of cartilage cells

Breast cancer drug offers protection against obesity-related metabolic disorders

Scientists identify unusual mutations in endometriosis using gene sequencing tools

Sangamo Therapeutics and Pfizer team up for development of Hemophilia A gene therapy

Study generates comprehensive catalog of diseases linked to variations in HLA genes

Early-onset pancreatitis in children linked to family history and genetic mutations

UT Health scientists discover epigenetic changes that contribute to AML

Gut microbiome may play key role in pathology of common cerebrovascular disease

UC researchers find stem cell vaccine to enhance immune responses against tumors in animal models

New findings pinpoint key feature of rare childhood disease that could help fast-track diagnosis

Serum Institute signs licensing agreement to commercialize St. Jude vaccine against RSV

Children's bone health could be determined before birth, study shows

Researchers uncover structure of embryo-protecting protein

Studies pave way for genome-targeted treatments in pancreatic cancer

Study findings could help identify treatments for balding and hair graying

BGRF scientists help develop AI to expedite drug development for age-related conditions

UVA research finding sheds light on cause of deadly heart condition

eBook: Using iPSCs models for human disease research and drug discovery eBook

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research