Gene News and Research

Latest Gene News and Research

UT Southwestern researchers uncover mechanism linked to balding and hair graying

UT Southwestern Medical Center researchers have identified the cells that directly give rise to hair as well as the mechanism that causes hair to turn gray - findings that could one day help identify possible treatments for balding and hair graying.

9 May 2017

Study reveals role of good-guy protein in initiating and maintaining cancer

Under normal conditions, the CHD4 protein is one of the good guys: it stops cells from transcribing faulty DNA, thereby eliminating potential mutation. But in colon cancer and perhaps other kinds of cancer as well, it appears that this protein becomes a kind of double agent, working for the enemy.

9 May 2017

Study findings shed new light on evolution and interaction of ancient proteins

How did protein interactions arise and how have they developed? In a new study, researchers have looked at two proteins which began co-evolving between 400 and 600 million years ago.

9 May 2017

Study findings suggest how progranulin deficiency causes frontotemporal dementia

In a recent study in Human Molecular Genetics, researchers from VIB and KU Leuven led by prof. Philip Van Damme, reveal a novel function for progranulin in lysosomes: it acts as chaperone of the lysosomal protease cathepsin D. The results were obtained in collaboration with Prof. Paul Saftig from the University of Kiel.

8 May 2017

Choice of fat causes distinct epigenetic changes in human adipose tissue, study shows

Previous research has demonstrated that saturated fat is more fattening and less muscle building than polyunsaturated fats. A new study shows that the choice of fat causes epigenetic changes which in turn could contribute to differences in fat storage.

8 May 2017

Energy drinks linked to risk of cardiac events in young people with familial long QT syndrome

Caffeinated energy drinks can trigger serious cardiac events including cardiac arrest in individuals not known to have a specific heart disease of genetic origin.

8 May 2017

Study uncovers potential new therapeutic targets for HCV infections

An international study led by researchers at Monash University' Biomedicine Discovery Institute (BDI) has shone light on the way the Hepatitis C Virus (HCV) hijacks the communication systems in the host cells it infects, uncovering potential new therapeutic targets for the disease.

8 May 2017

WHO to launch pilot project for prequalifying biosimilar cancer medicines

This year WHO will launch a pilot project for prequalifying biosimilar medicines, a step towards making some of the most expensive treatments for cancer more widely available in low- and middle-income countries.

8 May 2017

Specific genotype may predict recovery in patients with advanced cirrhosis after hepatitis c treatment

Genotyping of patients with advanced cirrhosis from hepatitis C virus could help health-care professionals predict the likelihood of improvement after successful hepatitis C treatment, thus minimizing the need for liver transplants.

8 May 2017

Research in people with IBS shows link between gut microbiota and brain regions

A new study by researchers at UCLA has revealed two key findings for people with irritable bowel syndrome about the relationship between the microorganisms that live in the gut and the brain.

5 May 2017

Study shows how influenza A hijacks human cellular machinery to replicate

Much is known about flu viruses, but little is understood about how they reproduce inside human host cells, spreading infection. Now, a research team headed by investigators from the Icahn School of Medicine at Mount Sinai is the first to identify a mechanism by which influenza A, a family of pathogens that includes the most deadly strains of flu worldwide, hijacks cellular machinery to replicate.

5 May 2017

Novel approach cures diabetes in mice for one year without side effects

A potential cure for Type 1 diabetes looms on the horizon in San Antonio, and the novel approach would also allow Type 2 diabetics to stop insulin shots.

5 May 2017

Study identifies potent molecular mechanism for insecticide resistance in sandfly species

A study led by LSTM identifies a potent molecular mechanism for insecticide resistance in the world's most medically-important sandfly species and develops DNA-diagnostics for monitoring future impact on visceral leishmaniasis control and elimination programs.

5 May 2017

FDA approves new AML drug after clinical testing at Dana-Farber

A targeted drug whose clinical testing was led by Richard Stone, MD, of Dana-Farber Cancer Institute, has become the first new treatment for newly diagnosed acute myeloid leukemia (AML) in more than 25 years.

5 May 2017

Researchers pinpoint gene that plays crucial role in formation of neural tube defects

Researchers have identified a gene that plays a key role in the formation of neural tube defects, a problem commonly found in infants of pregnant women with diabetes.

5 May 2017

New technique improves accuracy, reduces costs of real-time assessment of kidney function

A new technique developed by researchers at Lawrence Livermore National Lab promises to improve accuracy and lower costs of real-time assessment of kidney function, reports an article published this week by SPIE, the international society for optics and photonics, in the Journal of Biomedical Optics.

5 May 2017

Scientists identify RIOK1 enzyme as new target for cancer therapy

Dr. Florian Weinberg, from Prof. Dr. Tilman Brummer's research group at the Institute of Molecular Medicine and Cell Research of the University of Freiburg, joined forces with scientists from the Departments of Clinical Pathology and Medicine I of the University Medical Centre Freiburg and the Kinghorn Cancer Centre/Garvan Insitute in Australia in an international team that has identified a new target for cancer therapy.

5 May 2017

Study reveals critical role of omega-3 fatty acids in preserving integrity of the blood-brain barrier

Already extolled for their health benefits as a food compound, omega-3 fatty acids now appear to also play a critical role in preserving the integrity of the blood-brain barrier, which protects the central nervous system from blood-borne bacteria, toxins and other pathogens, according to new research from Harvard Medical School.

5 May 2017

Easing cellular traffic jams in Huntington’s disease may save brain cells

Working with mouse, fly and human cells and tissue, Johns Hopkins researchers report new evidence that disruptions in the movement of cellular materials in and out of a cell's control center - the nucleus- appear to be a direct cause of brain cell death in Huntington's disease, an inherited adult neurodegenerative disorder.

5 May 2017

Researchers uncover unexpected mechanism of glucose sensing in skeletal muscles

It's obvious that the taste buds on the tongue can detect sugar. And after a meal, beta cells in the pancreas sense rising blood glucose and release the hormone insulin - which helps the sugar enter cells, where it can be used by the body for energy.

5 May 2017

Gene News and Research

Latest Gene News and Research

UT Southwestern researchers uncover mechanism linked to balding and hair graying

Study reveals role of good-guy protein in initiating and maintaining cancer

Study findings shed new light on evolution and interaction of ancient proteins

Study findings suggest how progranulin deficiency causes frontotemporal dementia

Choice of fat causes distinct epigenetic changes in human adipose tissue, study shows

Energy drinks linked to risk of cardiac events in young people with familial long QT syndrome

Study uncovers potential new therapeutic targets for HCV infections

WHO to launch pilot project for prequalifying biosimilar cancer medicines

Specific genotype may predict recovery in patients with advanced cirrhosis after hepatitis c treatment

Research in people with IBS shows link between gut microbiota and brain regions

Study shows how influenza A hijacks human cellular machinery to replicate

Novel approach cures diabetes in mice for one year without side effects

Study identifies potent molecular mechanism for insecticide resistance in sandfly species

FDA approves new AML drug after clinical testing at Dana-Farber

Researchers pinpoint gene that plays crucial role in formation of neural tube defects

New technique improves accuracy, reduces costs of real-time assessment of kidney function

Scientists identify RIOK1 enzyme as new target for cancer therapy

Study reveals critical role of omega-3 fatty acids in preserving integrity of the blood-brain barrier

Easing cellular traffic jams in Huntington’s disease may save brain cells

Researchers uncover unexpected mechanism of glucose sensing in skeletal muscles

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Advancing brain microphysiological systems (bMPS)

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Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research