Gene News and Research

Latest Gene News and Research

Testing for Lynch syndrome: an interview with Kevin Monahan

Lynch syndrome is an inherited condition which causes about 1,100 cases of bowel cancer and 1,000 other cancers annually in the UK. It is caused by a fault in the mismatch repair gene (MMR) which usually works to prevent cancer.

21 Nov 2016

New study shows link between defective sucrase-isomaltase gene variants and IBS

Irritable bowel syndrome (IBS) affects a large portion of the general population. New research coordinated by Karolinska Institutet now shows a link between defective sucrase-isomaltase gene variants and IBS.

21 Nov 2016

New study describes role of protein that is crucial for melanoma cell survival

The main goals of the Melanoma Group at the Spanish National Cancer Research Centre are to identify biomarkers of tumour progression and to validate novel therapeutic targets in melanoma.

21 Nov 2016

Scientists uncover novel process by which APOL1 gene contributes to renal disease

A Children's National Health System research team has uncovered a novel process by which the gene APOL1 contributes to renal disease, according to a paper published November 18 in the Journal of the American Society of Nephrology.

18 Nov 2016

Scientists capture DNA intermediates that reveal how cancer evolves

Scientists from Rice University, Baylor College of Medicine and other institutions are using synthetic biology to capture elusive, short-lived snippets of DNA that healthy cells produce on their way to becoming cancerous.

18 Nov 2016

Würzburg researchers develop novel technique to provide new insight into Salmonella infection process

Technological advances are making the analysis of single bacterial infected human cells feasible, Würzburg researchers have used this technology to provide new insight into the Salmonella infection process.

18 Nov 2016

New research shows immune paralysis in sepsis patients can be reversed

Failure of the immune system during blood poisoning (sepsis) can be reversed by a specific sugar.

18 Nov 2016

Implementation of large-scale genomic tumor profiling viable but faces several challenges

Researchers leading the largest genomic tumor profiling effort of its kind say such studies are technically feasible in a broad population of adult and pediatric patients with many different types of cancer, and that some patients can benefit by receiving precision drugs targeted to their tumors' mutations or being enrolled in clinical trials.

18 Nov 2016

Most rapid diagnostic tests fail to detect P. falciparum malaria parasites in asymptomatic children

The Democratic Republic of the Congo has one of the highest rates of people living with malaria. Rapid diagnostic tests (RDTs) account for more than 70 percent of diagnostic testing for malaria in Africa.

17 Nov 2016

Scientists map reorganization of genetic material in cells using 3-D imaging technique

Scientists have mapped the reorganization of genetic material that takes place when a stem cell matures into a nerve cell.

17 Nov 2016

BAG3 protein plays protective role by limiting reperfusion injury to the heart

The inability of cells to eliminate damaged proteins and organelles following the blockage of a coronary artery and its subsequent re-opening with angioplasty or medications - a sequence known as ischemia/reperfusion - often results in irreparable damage to the heart muscle.

17 Nov 2016

Johns Hopkins researchers develop new, highly accurate urine test to predict risk for cervical cancer

Johns Hopkins Medicine specialists report they have developed a urine test for the likely emergence of cervical cancer that is highly accurate compared to other tests based on genetic markers derived directly from cervical tissue.

17 Nov 2016

Veterans Affairs researchers discover alleles of certain genes that offer protection from GWI

Veterans Affairs researchers have found that certain forms, or alleles, of a gene known to play a key role in the immune system appear to offer protection from Gulf War illness (GWI). Further, they discovered how such protection is manifested in the brain.

17 Nov 2016

Sleep apnea can make lung cancer more dangerous by increasing tumor growth

A team of researchers from the University of Chicago and the University of Barcelona has found that intermittent hypoxia, or an irregular lack of air experienced by people with sleep apnea, can increase tumor growth by promoting the release of circulating exosomes.

17 Nov 2016

HC-based NGS helps detect genomic alterations not identified in routine lung cancer screening

The use of hybrid capture-based (HC-based) next-generation sequencing (NGS) to identify targetable oncogenic drivers in patients with lung adenocarcinoma results in the detection of genomic alterations (GAs) not identified in routine screening, and impacts treatment decisions and clinical outcomes.

17 Nov 2016

Researchers identify pathway that helps cancer cells to aggressively spread in the brain

Glioblastoma multiforme remains the most common and highly lethal brain cancer and is known for its ability to relapse.

17 Nov 2016

Researchers discover molecular pathway that plays major role in maintaining normal kidney function

Boston University researchers, in collaboration with Centers for Therapeutic Innovation at Pfizer Inc., have discovered a novel molecular pathway needed to regulate kidney podocytes--special octopus-like cells that are critical in maintaining normal kidney function.

17 Nov 2016

Gene News and Research

Latest Gene News and Research

Testing for Lynch syndrome: an interview with Kevin Monahan

New study shows link between defective sucrase-isomaltase gene variants and IBS

New study describes role of protein that is crucial for melanoma cell survival

Scientists uncover novel process by which APOL1 gene contributes to renal disease

Scientists capture DNA intermediates that reveal how cancer evolves

Würzburg researchers develop novel technique to provide new insight into Salmonella infection process

New research shows immune paralysis in sepsis patients can be reversed

Implementation of large-scale genomic tumor profiling viable but faces several challenges

Most rapid diagnostic tests fail to detect P. falciparum malaria parasites in asymptomatic children

Scientists map reorganization of genetic material in cells using 3-D imaging technique

BAG3 protein plays protective role by limiting reperfusion injury to the heart

Johns Hopkins researchers develop new, highly accurate urine test to predict risk for cervical cancer

Veterans Affairs researchers discover alleles of certain genes that offer protection from GWI

Sleep apnea can make lung cancer more dangerous by increasing tumor growth

HC-based NGS helps detect genomic alterations not identified in routine lung cancer screening

Researchers identify pathway that helps cancer cells to aggressively spread in the brain

Researchers discover molecular pathway that plays major role in maintaining normal kidney function

Researchers need to know more about proinsulin misfolding to better understand diabetes

Scientists identify mutations in three genes linked to uncombable hair syndrome

Researchers create temporal and spatial atlas that plots development of mouse heart

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