IQuity launches pioneering RNA-based blood test to diagnose fibromyalgia

Groundbreaking test identifies gene expression pattern consistent with fibromyalgia syndrome, providing information that can speed pace of diagnosis

Nashville-based data science company IQuity has announced the release of IsolateFibromyalgia, a pioneering blood test that uses RNA analysis to help health care providers accurately and quickly detect fibromyalgia syndrome.

IsolateFibromyalgia uses a simple blood draw to detect, with 94 percent accuracy, if a patient’s gene expression pattern is consistent with fibromyalgia syndrome. Providers who suspect fibromyalgia in a patient can order the test at, with results delivered back to the provider within seven days of receiving the sample in the laboratory — reducing by months and even years the time it currently takes to diagnose the disease.

“RNA analysis is a cutting-edge tool for doctors that has great potential in the field of medical diagnostics,” said Dr. Chase Spurlock, CEO of IQuity. “Unlike DNA, which can predict the risk of certain diseases, RNA shows what’s taking place right now in a patient’s cells. That information can speed up the pace of diagnosis for physicians, leading to faster, more effective treatment for patients.”

The extensive disease controls used in the creation of IsolateFibromyalgia make the test highly accurate in differentiating fibromyalgia from conditions that it mimics or that could be misdiagnosed as fibromyalgia. IQuity’s researchers examined approximately 600 samples from patients suffering from a number of conditions, including fibromyalgia, rheumatoid arthritis, systemic lupus and clinically diagnosed depression, as well as healthy patients.

Fibromyalgia is a central nervous system disorder that affects between 6 and 12 million Americans, according to the American Chronic Pain Association. Its symptoms vary among patients, but many struggle with intense pain throughout the body, as well as fatigue, depression and difficulty concentrating.

“Living with the pain of fibromyalgia is often compounded with confusion and uncertainty when patients don’t know the cause of their illness,” said Spurlock. “IsolateFibromyalgia provides useful information that improves the efficiency of the diagnostic process for doctors.”

IQuity has previously released two other tests: IsolateMS, for multiple sclerosis, and IsolateIBS-IBD™, for irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD), which includes Crohn’s disease and ulcerative colitis. All three tests were developed using the proprietary IQIsolate technology, which applies machine-learning methods to create a suite of algorithms that compares the RNA profile from patient blood samples against a robust data set of healthy and sick patients identified through IQuity’s research.



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