Gene News and Research

Latest Gene News and Research

Brain-derived neurotrophic factor linked to slower cognitive decline in older people

Older people with higher amounts of a key protein in their brains also had slower decline in their memory and thinking abilities than people with lower amounts of protein from the gene called brain-derived neurotrophic factor, or BDNF, according to a study published in the January 27, 2016, online issue of Neurology, the medical journal of the American Academy of Neurology.

28 Jan 2016

New findings offer roadmap for development of novel therapies to target common brain disorders

Scientists have pinpointed the cells that are likely to trigger common brain disorders, including Alzheimer's disease, Multiple Sclerosis and intellectual disabilities.

28 Jan 2016

CUMC, Iowa scientists use CRISPR to repair genetic mutation responsible for retinitis pigmentosa

Columbia University Medical Center and University of Iowa scientists have used a new gene-editing technology called CRISPR, to repair a genetic mutation responsible for retinitis pigmentosa (RP), an inherited condition that causes the retina to degrade and leads to blindness in at least 1.5 million cases worldwide.

28 Jan 2016

Stopping disruptions in cellular 'trash removal' may guard against neurodegenerative diseases

Stopping disruptions in cellular "trash removal" brought on by errors in molecular marks on DNA may guard against neurodegenerative diseases like Parkinson's.

27 Jan 2016

DNA imprinting defect may affect children diagnosed with osteosarcoma

Children diagnosed with osteosarcoma may be impacted by a DNA imprinting defect also found in parents, according to new research from the Masonic Cancer Center, University of Minnesota. DNA imprinting is a phenomenon in which just one of the two inherited genes is active while the other is present but inactive.

27 Jan 2016

Patients who receive information about coronary artery disease risk make improvements to health behaviors

A new study led by researchers at Brigham and Women's Hospital has found that providing unanticipated information about risk of coronary artery disease during a genetic risk assessment for Alzheimer's disease helped some participants cope with their results, and also motivated participants to make changes to their health behaviors.

27 Jan 2016

Study identifies potential therapeutic targets for treatment of multiple sclerosis

Treatment of multiple sclerosis (MS) and other inflammatory diseases may benefit by new findings from a study that identified potential therapeutic targets for a devastating disease striking some 2.3 million people worldwide.

26 Jan 2016

STAT4 variant predicts HBV IFNα response

Variation in the STAT4 gene is associated with response to interferon (IFN)α therapy in patients with hepatitis B e antigen-positive chronic hepatitis B virus infection, suggests research published in Hepatology.

26 Jan 2016

Genetic code and epigenetics revealing adaption traits

A well-known songbird, the great tit, has revealed its genetic code, offering researchers new insight into how species adapt to a changing planet. Their initial findings suggest that epigenetics -- what's on rather than what's in the gene -- may play a key role in the evolution of memory and learning. And that's not just true for birds.

26 Jan 2016

New study aims to prevent chronic cardiac failure

Researchers at Osaka University clarified that the cell adhesion inhibition of periostin1 damages myocardinal cells, inducing compromised cardiac myocyte contractile force and myocytes death, leading to the onset of cardiac failure after AMI through the administration of periostin neutralizing antibodies they had developed on their own.

26 Jan 2016

Specific genetic pattern in the womb could predict IVF treatment outcome

Fertility experts in Southampton and the Netherlands have identified a specific genetic pattern in the womb that could predict whether or not IVF treatment is likely to be successful.

25 Jan 2016

New €5.6 million project aims to develop cell-based haemophilia A therapy

Loughborough University is working with a team of international partners on a new €5.6 million project to develop a cell based haemophilia A therapy.

25 Jan 2016

BCR–ABL transcript type linked to TKI response, outcomes

The type of BCR–ABL transcript could have an impact on tyrosine kinase inhibitor choice in patients with chronic myeloid leukaemia , according to research published in Blood.

22 Jan 2016

PGD model could provide policy guideposts for human genome editing

Human genome editing for both research and therapy is progressing, raising ethical questions among scientists around the world.

22 Jan 2016

Sensitive computational method could help reveal effect of the immune system on cancer

A study by researchers at Norris Cotton Cancer Center has shown that a very sensitive computational method can be used to reveal the human immune system's effect on cancer. The Dartmouth study was the first to perform an in-depth computational examination of how immune activity translates to prognosis in breast cancer.

22 Jan 2016

Colon cancer patients lacking CDX2 protein more likely to benefit from chemotherapy

Using a new computer science approach, researchers at University of California, San Diego School of Medicine, Columbia University and Stanford University discovered a distinctive molecular feature — a biomarker — that identified colon cancer patients who were most likely to remain disease-free up to five years after surgery.

22 Jan 2016

CU Cancer Center study finds distinct genetic drivers of colorectal cancer in younger and older patients

A University of Colorado Cancer Center study being presented Saturday at the 2016 Genitourinary Cancers Symposium shows genetic differences between colorectal cancer (CRC) in young and old patients, possibly pointing toward different treatments and strategies in combating the young form of the disease.

22 Jan 2016

Oral drug ivacaftor appears to be safe, beneficial to pre-school children with specific type of cystic fibrosis

The oral drug ivacaftor appears to be safe and could be beneficial to young children between the ages of 2 and 5 with a specific type of cystic fibrosis, according to new research published in The Lancet Respiratory Medicine journal.

22 Jan 2016

Amgen announces approval of cholesterol-lowering medication Repatha (evolocumab) Injection in Japan

Amgen today announced that the Japanese Ministry of Health, Labour and Welfare has approved the cholesterol-lowering medication Repatha (evolocumab) Injection, the first proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor to be approved in Japan.

22 Jan 2016

Simple blood test could predict relapse in AML patients

A simple blood test capable of detecting trace levels of leukaemia cells remaining after intensive chemotherapy has been developed by scientists at the National Institute for Health Research Biomedical Research Centre at Guy’s and St Thomas’ NHS Foundation Trust and King’s College London.

22 Jan 2016

Gene News and Research

Latest Gene News and Research

Brain-derived neurotrophic factor linked to slower cognitive decline in older people

New findings offer roadmap for development of novel therapies to target common brain disorders

CUMC, Iowa scientists use CRISPR to repair genetic mutation responsible for retinitis pigmentosa

Stopping disruptions in cellular 'trash removal' may guard against neurodegenerative diseases

DNA imprinting defect may affect children diagnosed with osteosarcoma

Patients who receive information about coronary artery disease risk make improvements to health behaviors

Study identifies potential therapeutic targets for treatment of multiple sclerosis

STAT4 variant predicts HBV IFNα response

Genetic code and epigenetics revealing adaption traits

New study aims to prevent chronic cardiac failure

Specific genetic pattern in the womb could predict IVF treatment outcome

New €5.6 million project aims to develop cell-based haemophilia A therapy

BCR–ABL transcript type linked to TKI response, outcomes

PGD model could provide policy guideposts for human genome editing

Sensitive computational method could help reveal effect of the immune system on cancer

Colon cancer patients lacking CDX2 protein more likely to benefit from chemotherapy

CU Cancer Center study finds distinct genetic drivers of colorectal cancer in younger and older patients

Oral drug ivacaftor appears to be safe, beneficial to pre-school children with specific type of cystic fibrosis

Amgen announces approval of cholesterol-lowering medication Repatha (evolocumab) Injection in Japan

Simple blood test could predict relapse in AML patients

eBook: Using iPSCs models for human disease research and drug discovery eBook

How the Vutara VXL simplifies single-molecule imaging

How cohesin mechanics and nanotracker tech are redefining DNA research

Todd Bauman and Chris Povich