Gene News and Research

Latest Gene News and Research

Understanding the brain's cellular building blocks

Understanding the cellular building blocks of the brain, including the number and diversity of cell types, is a fundamental step toward understanding brain function. Researchers at the Allen Institute for Brain Science have created a detailed taxonomy of cells in the mouse visual cortex based on single-cell gene expression, identifying 49 distinct cell types in the largest collection of individual adult cortical neurons characterized by gene expression published to date.

5 Jan 2016

People can use physically active lifestyle to reduce effect of inherited obesity genes

People from around the world can use a physically active lifestyle to blunt the effect of inherited obesity genes, McMaster University researchers have found.

5 Jan 2016

Researchers discover methods for reducing age-related stem cell dysfunction, metabolic disease in aged mice

Mayo Clinic researchers have taken what they hope will be the first step toward preventing and reversing age-related stem cell dysfunction and metabolic disease. That includes diabetes, which affects 12.2 million Americans age 60 and older, according to the National Council on Aging.

5 Jan 2016

High diversity among circulating tumor cells predicts survival, treatment resistance in prostate cancer patients

Research teams at Memorial Sloan Kettering Cancer Center and Epic Sciences have found that greater diversity among circulating tumor cells (CTCs) in the blood of advanced prostate cancer patients predicts not only shorter overall survival, but also the development of resistance to key anti-androgen therapies.

4 Jan 2016

UT Southwestern scientists use new gene-editing technique to prevent progression of DMD in young mice

Using a new gene-editing technique, a team of scientists from UT Southwestern Medical Center stopped progression of Duchenne muscular dystrophy (DMD) in young mice.

4 Jan 2016

World's largest database for cancer drug discovery revolutionised by 3D techniques

THE world's largest database for cancer drug discovery has been revolutionised by adding 3D structures of faulty proteins and maps of cancer's communication networks, according to Cancer Research UK-funded research published in Nucleic Acid Research today (Monday).

4 Jan 2016

NCCLC patients with KRAS-related gene mutations may benefit from triple therapy

Although the most common type of lung cancer - non-small cell lung cancer (NSCLC) - has recently seen major treatment advances in some genetic subtypes, other subtypes continue to evade effective treatment. (New therapies exist for NCCLC patients whose cancers harbor mutations in the ALK or EGFR genes, for example.)

4 Jan 2016

New Penn study shows that social behavior in carpenter ants can be reprogrammed

In Florida carpenter ant colonies, distinct worker castes called minors and majors exhibit pronounced differences in social behavior throughout their lives. In a new study published today in Science, a multi-institution team anchored at University of Pennsylvania found that these caste-specific behaviors are not set in stone.

4 Jan 2016

Study unravels mechanisms by which saffron-based crocin prevents liver cancer

Liver cancer remains among the leading causes of cancer-related death worldwide. New study lead by UAE University Prof. Amr Amin unravels mechanisms by which saffron-based 'crocin' protects against liver cancer.

4 Jan 2016

Researchers successfully use CRISPR to treat adult mouse model of Duchenne muscular dystrophy

Researchers have used CRISPR to treat an adult mouse model of Duchenne muscular dystrophy. This marks the first time that CRISPR has successfully treated a genetic disease inside a fully developed living mammal with a strategy that has the potential to be translated to human therapy.

4 Jan 2016

St. Jude scientists develop interactive tool to advance understanding of mutations that fuel pediatric cancer

St. Jude Children's Research Hospital scientists have developed a web application and data set that gives researchers worldwide a powerful interactive tool to advance understanding of the mutations that lead to and fuel pediatric cancer. The freely available tool, called ProteinPaint, is described in today's issue of the scientific journal Nature Genetics.

30 Dec 2015

Several therapies for hemophilia A, hemophilia B and hemophilia with inhibitors to be launched between 2015-2025

Decision Resources Group forecasts that several therapies will launch for hemophilia A, hemophilia B and hemophilia with inhibitors in the United States and Europe during our 2015-2025 study period.

29 Dec 2015

UAB's Undiagnosed Diseases Program finds answers for mysterious health issues

Stephanie and Christopher Smith have been on a long, difficult and often frustrating journey to find answers for the mysterious health issues of their children. It started 24 years ago when their third child, Gage, was born. Gage, his younger brother Aiden and then sister Mandalynn, now 13, all developed mysterious symptoms that mystified doctors.

29 Dec 2015

Scientists pin down structure of neuronal protein clumps associated with ALS

To create treatments for a disease without any, scientists need to study and understand the driving forces behind the faulty biology. Today, researchers at the University of North Carolina School of Medicine announced the first-ever evidence-based description of the neuronal protein clumps thought to be important in Amyotrophic Lateral Sclerosis (ALS), also known as Lou Gehrig's disease, a fatal neurodegenerative condition.

29 Dec 2015

New study identifies activity of brain proteins linked to memory impairments in Alzheimer's disease

A new study conducted at the University of Haifa and published recently in the Journal of Neuroscience has identified activity of brain proteins associated with memory impairments in Alzheimer's disease, and has also found that "repairing" this activity leads to an improvement in memory.

29 Dec 2015

Researchers identify inherited traits related to sleep, wake and activity cycles

In the first study of its kind, a team of international scientists led by UT Southwestern Medical Center and UCLA researchers have identified a dozen inherited traits related to sleep, wake, and activity cycles that are associated with severe bipolar disorder.

29 Dec 2015

Infusing small dose of cytokine can prevent or reverse diabetes-related kidney failure

Diabetes is the leading cause of kidney failure, and scientists have found that infusing just a small dose of a cytokine, thought to help cause that failure, can instead prevent or reverse it.

29 Dec 2015

Genetic modification in esophagus can lead to esophageal cancer

A genetic modification in the mucous membrane of the esophagus, the Barrett esophagus, can lead to esophageal cancer. If certain biomarkers are contained in these tissue alterations, so-called miDNA, these are extremely short DNA strands, it could be an indication that this preliminary stage of esophageal cancer indeed leads to cancer.

28 Dec 2015

Researchers identify new gene that helps maintain chromosome number in cells

Molecular biologists at UT Southwestern Medical Center have identified a gene called NORAD that helps maintain the proper number of chromosomes in cells, and that when inactivated, causes the number of chromosomes in a cell to become unstable, a key feature of cancer cells.

26 Dec 2015

3D maps of spatial organization may help find genes involved in hereditary diseases

It has now been 15 years since scientists celebrated the completion of the human genome. At that point, scientists had determined the entire sequence of the genetic letters making up our DNA.

26 Dec 2015

Gene News and Research

Latest Gene News and Research

Understanding the brain's cellular building blocks

People can use physically active lifestyle to reduce effect of inherited obesity genes

Researchers discover methods for reducing age-related stem cell dysfunction, metabolic disease in aged mice

High diversity among circulating tumor cells predicts survival, treatment resistance in prostate cancer patients

UT Southwestern scientists use new gene-editing technique to prevent progression of DMD in young mice

World's largest database for cancer drug discovery revolutionised by 3D techniques

NCCLC patients with KRAS-related gene mutations may benefit from triple therapy

New Penn study shows that social behavior in carpenter ants can be reprogrammed

Study unravels mechanisms by which saffron-based crocin prevents liver cancer

Researchers successfully use CRISPR to treat adult mouse model of Duchenne muscular dystrophy

St. Jude scientists develop interactive tool to advance understanding of mutations that fuel pediatric cancer

Several therapies for hemophilia A, hemophilia B and hemophilia with inhibitors to be launched between 2015-2025

UAB's Undiagnosed Diseases Program finds answers for mysterious health issues

Scientists pin down structure of neuronal protein clumps associated with ALS

New study identifies activity of brain proteins linked to memory impairments in Alzheimer's disease

Researchers identify inherited traits related to sleep, wake and activity cycles

Infusing small dose of cytokine can prevent or reverse diabetes-related kidney failure

Genetic modification in esophagus can lead to esophageal cancer

Researchers identify new gene that helps maintain chromosome number in cells

3D maps of spatial organization may help find genes involved in hereditary diseases

eBook: Using iPSCs models for human disease research and drug discovery eBook

How the Vutara VXL simplifies single-molecule imaging

How cohesin mechanics and nanotracker tech are redefining DNA research

Todd Bauman and Chris Povich