Gene News and Research

Latest Gene News and Research

Set of genes identified in human genome essential for survival, proliferation of human cell lines

Using two complementary analytical approaches, scientists at Whitehead Institute and Broad Institute of MIT and Harvard have for the first time identified the universe of genes in the human genome essential for the survival and proliferation of human cell lines or cultured human cells.

16 Oct 2015

Study identifies proteins that could help in treating deafness

Almost 40 million Americans suffer from hearing loss. Right now, there is no way to reverse this condition, largely because auditory hair cells, which sense sound and relay that information to the brain, do not regenerate.

16 Oct 2015

Study shows why cancer anemia therapy stimulates tumor growth

Scientists have shown why a drug widely used to treat chemotherapy-induced anemia in ovarian and breast cancer patients also may shorten survival times in some patients by inadvertently stimulating tumor growth.

16 Oct 2015

Scientists use new technology to create gene expression map of inner ear cell development

Using a sensitive new technology called single-cell RNA-seq on cells from mice, scientists have created the first high-resolution gene expression map of the newborn mouse inner ear.

16 Oct 2015

US and German researchers team up to advance quality control of human stem cells

Researchers at The Scripps Research Institute (TSRI) in California, USA, and two German institutes, the Center for Integrated Psychiatry Kiel (ZIP) and the Fraunhofer Institute for Molecular Biology and Applied Ecology IME, have announced a partnership to advance the quality control of human stem cells.

16 Oct 2015

Rare disease diagnosis available in days not years: BIA announcement

It currently takes 5 years on average to diagnose a child with a rare genetic disease, so he or she can receive the most appropriate care. This is set to change with an agreement facilitated by Northern Health Science Alliance (NHSA) between Congenica and 5 of its member hospitals, which will see them adopt the company’s world leading Sapientia™ technology.

16 Oct 2015

Gene therapy preserves vision in canine model of late-stage retinitis pigmentosa

Gene therapy preserved vision in a study involving dogs with naturally occurring, late-stage retinitis pigmentosa, according to research funded by the National Eye Institute (NEI), part of the National Institutes of Health. The findings contribute to the groundwork needed to move gene therapy forward into clinical trials for people with the blinding eye disorder, for which there is currently no cure.

15 Oct 2015

Specific gene signature could help predict survival outcomes among children with intermediate-risk RMS

Among children with intermediate-risk rhabdomyosarcoma (RMS) that is negative for a fusion gene, those who had a high score of a specific gene signature called MG5 had poorer survival outcomes compared with those who had a low score of MG5.

15 Oct 2015

New blood test could help pair cancer patients with suitable therapy for their disease

CANCER RESEARCH UK-funded scientists have developed a blood test that could help pair cancer patients with the most suitable therapy for their disease and then track the tumour's progress to see if the treatment is working, according to research published today (Thursday) in Clinical Cancer Research.

15 Oct 2015

enGene, Janssen Biotech sign agreement to develop and commercialize new IBD therapies

enGene, Inc. a gene therapy company focused on development of therapeutics using its proprietary "Gene Pill" and enema gene delivery platform, today announced that it has entered into a definitive agreement with Janssen Biotech, Inc., one of the Janssen Pharmaceutical Companies of Johnson & Johnson, to develop and commercialize new therapies for inflammatory bowel disease (IBD).

14 Oct 2015

New hope for patients with Duchenne muscular dystrophy

New hope for Duchenne muscular dystrophy (DMD) patients. A mouse genetic study in PLoS Medicine reports that targeting the P2RX7 gene, a purinoreceptor, may halt the progression of DMD.

14 Oct 2015

Thyroid hormone treatment improves cardiac health in female rats with high blood pressure

Thyroid hormones administered to female rats with high blood pressure led to encouraging cardiac improvements, according to a study in the American Journal of Physiology led by NYIT College of Osteopathic Medicine researcher Martin Gerdes.

14 Oct 2015

How important is a mother’s diet before pregnancy? An interview with Dr Matt Silver

In humans, much is already known about the impact of maternal undernutrition during pregnancy, and its impact on growth, development and disease throughout the life course. However, until recently little was known about the effects of the nutritional environment around the time of conception.

14 Oct 2015

Sense oligonucleotide antidote reverses actions of antisense antithrombotic drug, prevents bleeding

Researchers from Isis Pharmaceuticals (Carlsbad, CA) and Prysis Biotechnologies (Pudong, Shanghai, China) have demonstrated proof-of-concept for using a sense oligonucleotide to undo the effects of an antisense drug, an antithrombotic agent in this novel study.

14 Oct 2015

Researchers match certain schizophrenia symptoms to features of the brain's anatomy

Using advanced brain imaging, researchers have matched certain behavioral symptoms of schizophrenia to features of the brain's anatomy. The findings, at Washington University School of Medicine in St. Louis, could be a step toward improving diagnosis and treatment of schizophrenia.

14 Oct 2015

Researchers identify new therapeutic target for Duchenne muscular dystrophy

Scientists have found what could one day lead to a promising treatment for those with a crippling disease, Duchenne muscular dystrophy.

14 Oct 2015

New breakthrough may provide key to understanding how to treat Muscular Dystrophy

New research published today in the journal eLife has demonstrated a new method for observing the behaviour of the protein Dystrophin in a living animal cell, in real-time. This breakthrough may provide a key to understanding how to treat the genetic disease, Muscular Dystrophy.

14 Oct 2015

Blocking the production of CHD4 protein may help increase effectiveness of AML treatments

Preclinical experiments led by a team of researchers at VCU Massey Cancer Center have shown that blocking the production of a protein known as chromodomain helicase DNA-binding protein 4 (CHD4) may help increase the effectiveness of first-line treatments for acute myeloid leukemia (AML), a particularly lethal blood cancer that is increasing in incidence among older adults.

14 Oct 2015

UW researchers use noninvasive light-based imaging technology to see inside the living brain

Researchers at the University of Washington have used a noninvasive light-based imaging technology to literally see inside the living brain, providing a new tool to study how diseases like dementia, Alzheimer's, and brain tumors change brain tissue over time.

13 Oct 2015

Quest Diagnostics scientists demonstrate new molecular combing technique that predicts cystic fibrosis, muscular dystrophy

Genetic testing for mutations beyond those currently recommended in medical guidelines may aid the identification of more couples at risk of having a child with cystic fibrosis, according to a study presented today at the 2015 American Society of Human Genetics Annual Meeting, which runs through October 10 in Baltimore, Maryland.

From Quest Diagnostics 13 Oct 2015

Gene News and Research

Latest Gene News and Research

Set of genes identified in human genome essential for survival, proliferation of human cell lines

Study identifies proteins that could help in treating deafness

Study shows why cancer anemia therapy stimulates tumor growth

Scientists use new technology to create gene expression map of inner ear cell development

US and German researchers team up to advance quality control of human stem cells

Rare disease diagnosis available in days not years: BIA announcement

Gene therapy preserves vision in canine model of late-stage retinitis pigmentosa

Specific gene signature could help predict survival outcomes among children with intermediate-risk RMS

New blood test could help pair cancer patients with suitable therapy for their disease

enGene, Janssen Biotech sign agreement to develop and commercialize new IBD therapies

New hope for patients with Duchenne muscular dystrophy

Thyroid hormone treatment improves cardiac health in female rats with high blood pressure

How important is a mother’s diet before pregnancy? An interview with Dr Matt Silver

Sense oligonucleotide antidote reverses actions of antisense antithrombotic drug, prevents bleeding

Researchers match certain schizophrenia symptoms to features of the brain's anatomy

Researchers identify new therapeutic target for Duchenne muscular dystrophy

New breakthrough may provide key to understanding how to treat Muscular Dystrophy

Blocking the production of CHD4 protein may help increase effectiveness of AML treatments

UW researchers use noninvasive light-based imaging technology to see inside the living brain

Quest Diagnostics scientists demonstrate new molecular combing technique that predicts cystic fibrosis, muscular dystrophy

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