Genetics News and Research

Latest Genetics News and Research

Genetic variant linked to human height discovered

It became clear nearly a century ago that many genes likely influence how tall a person grows, though little progress, if any, has followed in defining the myriad genes. Now an international research team brings light to this age-old question by pinpointing a genetic variant associated with human height - the first consistent genetic link to be reported.

3 Sep 2007

Genetic-based dosing in orthopedic patients beginning warfarin therapy

Doctors prescribing blood thinners have had to go through a lengthy trial-and-error process to arrive at the optimal dose for their patients. But now the process can be faster and safer, thanks to research conducted at Washington University School of Medicine in St. Louis.

3 Sep 2007

A drug-sensitive 'traffic cop' tells potassium channels to get lost

Our brains are buzzing with electrical activity created by sodium and potassium ions moving in and out of neurons through specialized pores. To prevent the constant chatter from descending into chaos the activity of these ion channels has to be tightly regulated.

3 Sep 2007

Discovery suggests location of genes for breast density, a strong risk factor for breast cancer

Studying the DNA of 889 people, gene hunters at the Mayo Clinic and H. Lee Moffitt Cancer Centers have identified a region on chromosome 5p that is significantly associated with dense breast tissue, a known risk factor for breast cancer.

2 Sep 2007

Many city convenience stores lacking health foods

A survey of convenience stores in the south west section of Rochester has revealed that 95% offer little or no healthy foods.

30 Aug 2007

Small animal imaging facility is big boon to research

When powerful magnets line up the body's protons before radiofrequency waves can grab their attention away, it's called spin physics.

30 Aug 2007

One species' entire genome discovered inside another's

Scientists at the University of Rochester and the J. Craig Venter Institute have discovered a copy of the entire genome of a bacterial parasite residing inside the genome of its host species.

30 Aug 2007

Researchers chart the level of gene expression in melanoma cell lines

Other than visually inspecting the disease, doctors have no genetic blueprint to classify melanomas, a lethal form of skin cancer.

30 Aug 2007

New anti-cancer drug made from corn lillies kills brain tumor stem cells

A drug that shuts down a critical cell-signaling pathway in the most common and aggressive type of adult brain cancer successfully kills cancer stem cells thought to fuel tumor growth and help cancers evade drug and radiation therapy, a Johns Hopkins study shows.

30 Aug 2007

Resistance to some diseases may be genetic

According to a study in Evolution, resistance to certain infectious diseases may be passed genetically from parent to child.

30 Aug 2007

Contact disorder makes cancer cells mobile

The loss of the protein VMP1 in cancer cells increases their tendency to detach from the initial tumor - the first step towards metastasis.

30 Aug 2007

Binghamton University researchers investigate evolving malaria resistance

Funded by a $1.5 million grant from the National Institutes of Health, scientists at Binghamton University, State University of New York, hope to understand how the malaria parasite Plasmodium falciparum evolved resistance to the once-effective medication chloroquine.

30 Aug 2007

Researchers unlock mystery of a third olfactory system

Researchers at the University of Maryland School of Medicine have found a "nose within the nose," a unique olfactory system within the noses of mice that is able to "smell" hormones involved in regulating water and salt balance in the body.

30 Aug 2007

Big leap in genomic screening of blood vessels from patient tissue

Scientists have developed a new method of capturing a complete genome-wide screening of blood vessel cells in their actual disease state, advancing the potential for genetic research on the tissue responsible for delivering nourishment that can accelerate the growth of both a cancer tumor or wound healing.

30 Aug 2007

Ivermectin is causing genetic selection in river blindness parasite

Ivermectin, the standard drug for treating river blindness (onchocerciasis), is causing genetic changes in the parasite that causes the disease, according to a new study by Roger Prichard (McGill University, Canada) and colleagues, published on August 30, 2007 in the open-access journal PLoS Neglected Tropical Diseases.

30 Aug 2007

Genetics of imatinib resistance in acute lymphoblastic leukemia

In the September 15th issue of Genes & Development, Drs. Richard T. Williams, Willem den Besten, and Charles J. Sherr at Howard Hughes Medical Institute, St. Jude Children's Research Hospital in Memphis TN, lend new insights into how an aggressive form of acute lymphoblastic leukemia (ALL) develops, and how sensitivity to the targeted chemotherapeutic drug, imatinib, can be diminished through interactions between tumor cells and the host microenvironment.

30 Aug 2007

Gene regulation in humans is closer than expected to simple organisms

Gene networks are some of the most basic features of a living organism. An external or internal stimulus activates some genes, which in turn control others genes whose activity turns on or off various biological processes (such as the cell cycle, energy production, DNA repair, cellular suicide etc).

30 Aug 2007

1,000 strains of mice that feature the genetic diversity of the world population

Mice that are part of the Collaborative Cross project at Oak Ridge National Laboratory are helping scientists around the world learn more about possible causes of drug abuse, diabetes, sleep disorders, stress and pain, kidney disease and a number of other conditions that affect millions of people.

30 Aug 2007

Researchers discover what makes lymphomas tick

University of Pennsylvania researchers and their colleagues at the Wistar Institute and University of Oxford have discovered the molecular process by which the PAX5 protein, necessary for lymphocyte development, promotes the growth of common lymphomas, thereby unveiling a potential new target in the fight against cancer.

30 Aug 2007

FDA should amend the product information for irinotecan

Not everyone needs a genetic test before taking the cancer drug irinotecan, and the U.S. Food and Drug Administration should modify its prescription guidelines to say so, according to researchers at the University of North Carolina at Chapel Hill.

29 Aug 2007