Nervous System News and Research

Latest Nervous System News and Research

Oskar gene emerged far earlier in insect evolution than previously believed

Harvard scientists have solved the long-standing mystery of how some insects form the germ cells - the cellular precursors to the eggs and sperm necessary for sexual reproduction - and the answer is shedding new light on the evolutionary origins of a gene that had long been thought to be critical to the process.

2 Nov 2012

Study explores impact of IL1β on brain function alterations associated with schizophrenia

There are a growing number of clues that immune and inflammatory mechanisms are important for the biology of schizophrenia. In a new study in Biological Psychiatry, Dr. Mar Fatjó-Vilas and colleagues explored the impact of the interleukin-1β gene (IL1β) on brain function alterations associated with schizophrenia.

2 Nov 2012

Multiple sclerosis disease activity reduced by leukaemia drug, even when first-line treatment has failed

A drug which was originally developed to treat leukaemia and other cancers of the immune system offers substantial improvements over existing treatments in reducing relapse rates for people with multiple sclerosis (MS), even when they have not responded well to first-line treatment, according to the results of two phase 3 trials published Online First in The Lancet.

1 Nov 2012

Omeros initiates enrollment in OMS824 Phase 1 trial for schizophrenia and Huntington's

Omeros Corporation today announced that the first subject has been enrolled in the Company's Phase 1 clinical trial evaluating OMS824, the lead compound in Omeros' phosphodiesterase 10 (PDE10) program.

1 Nov 2012

Blocking hyaluronidase activity can help repair brain damage associated with MS

Researchers at Oregon Health & Science University have discovered that blocking a certain enzyme in the brain can help repair the brain damage associated with multiple sclerosis and a range of other neurological disorders.

1 Nov 2012

Dysfunction in SRGAP3 protein causes developmental brain disorders

A new research discovery has the potential to revolutionize the biological understanding of some childhood psychiatric disorders. Specifically, scientists have found that when a single protein involved in brain development, called "SRGAP3," is malformed, it causes problems in the brain functioning of mice that cause symptoms that are similar to some mental health and neurological disorders in children.

1 Nov 2012

Scientists discover first selective inhibitors of DAGL enzymes

Scientists at The Scripps Research Institute (TSRI) have discovered the first selective inhibitors of an important set of enzymes. The new inhibitors, and chemical probes based on them, now can be used to study the functions of enzymes known as diacylglycerol lipases (DAGL), their products, and the pathways they regulate.

1 Nov 2012

Additional data from EnVivo’s EVP-6124 Phase 2b trial on AD presented at CTAD meeting

EnVivo Pharmaceuticals, a company dedicated to developing a broad range of novel central nervous system (CNS) therapies, today presented pharmacokinetic and pharmacodynamic data along with the previously reported statistically significant clinical results from its Phase 2b clinical trial of EVP-6124, a novel alpha-7 agonist, in patients with Alzheimer's disease.

1 Nov 2012

Gene variant predicts lymphoma treatment response

German researchers have identified a gene variant that significantly influences the outcome of methotrexate therapy for primary central nervous system lymphoma.

31 Oct 2012

Vitamin D and multiple sclerosis: an interview with Ellen Mowry

Vitamin D is actually a hormone. For the most part, humans obtain vitamin D through sun exposure. Ultraviolet light from the sun promotes the conversion of a compound in the skin to pre-vitamin D.

31 Oct 2012

FDA accepts Sunovion’s two LATUDA sNDAs for review

Sunovion Pharmaceuticals Inc. today announced that the U.S. Food and Drug Administration (FDA) has accepted for review two supplemental New Drug Applications (sNDAs) for the use of LATUDA as 1) monotherapy and 2) adjunctive therapy to lithium or valproate, both to treat adult patients with depressive episodes associated with bipolar I disorder (bipolar depression).

31 Oct 2012

Top-line results from Neuraltus’ NP001 Phase 2 study on amyotrophic lateral sclerosis

Neuraltus Pharmaceuticals, a private biopharmaceutical company developing novel therapies for rare neurological disorders, announced today top-line results from the Company's Phase 2 clinical study of NP001 in patients with Amyotrophic Lateral Sclerosis (ALS, or Lou Gehrig's disease).

30 Oct 2012

Children with migraine more likely to have below average school performance

Children with migraine are more likely to have below average school performance than kids who do not have headaches, according to new research published in the October 30, 2012, print issue of Neurology-, the medical journal of the American Academy of Neurology.

30 Oct 2012

TTP488 slows cognitive decline in patients with mild to moderate Alzheimer's

A novel, orally administered drug candidate, TTP488, has demonstrated clinical evidence of slowing of cognitive decline over 18 months of therapy in patients with mild to moderate Alzheimer's disease.

30 Oct 2012

Scientists hope to unravel mystery of how Borrelia burgdorferi causes Lyme disease

Investigators at The University of Texas Health Science Center at Houston (UTHealth) have accelerated the search for the bacterial genes that make the Lyme disease bacterium so invasive and persistent. The discovery could advance the diagnosis and treatment of this disease, which affects an estimated 30,000 Americans each year.

29 Oct 2012

NewYork-Presbyterian/Columbia participates in Symplicity system trial for hypertension

Patients with hypertension whose blood pressure cannot be brought down to safe levels despite taking three or more medications may have some relief coming their way. An innovative, first-of-its-kind clinical trial for a device representing a dramatic shift in treatment approaches for the toughest-to-treat patients is currently being conducted at NewYork-Presbyterian Hospital.

From Medtronic 26 Oct 2012

Researchers discover genetic biomarker for age-related hearing loss

University of South Florida researchers have identified a genetic biomarker for age-related hearing loss, a major breakthrough in understanding and preventing a condition of aging that affects 30 million Americans and greatly diminishes their quality of life.

26 Oct 2012

BioLineRx intends to conduct interim analysis of BL-1020 Phase II/III trial for schizophrenia

BioLineRx, a biopharmaceutical development company, announced today that it intends to conduct an interim analysis of the Phase II/III CLARITY trial of BL-1020, a first in class, orally available, GABA-enhanced antipsychotic for the treatment of schizophrenia.

25 Oct 2012

Study finds high internet use by caregivers of children with hydrocephalus

When faced with disease, patients and caregivers now readily turn to the Internet for information and emotional support. This is particularly true in the case of caregivers of children with hydrocephalus.

25 Oct 2012

Hypnosis can help cut hot flashes by as much as 74%

Hypnosis can help cut hot flashes by as much as 74%, shows a study supported by the National Center for Complementary and Alternative Medicine.

25 Oct 2012

Nervous System News and Research

Latest Nervous System News and Research

Oskar gene emerged far earlier in insect evolution than previously believed

Study explores impact of IL1β on brain function alterations associated with schizophrenia

Multiple sclerosis disease activity reduced by leukaemia drug, even when first-line treatment has failed

Omeros initiates enrollment in OMS824 Phase 1 trial for schizophrenia and Huntington's

Blocking hyaluronidase activity can help repair brain damage associated with MS

Dysfunction in SRGAP3 protein causes developmental brain disorders

Scientists discover first selective inhibitors of DAGL enzymes

Additional data from EnVivo’s EVP-6124 Phase 2b trial on AD presented at CTAD meeting

Gene variant predicts lymphoma treatment response

Vitamin D and multiple sclerosis: an interview with Ellen Mowry

FDA accepts Sunovion’s two LATUDA sNDAs for review

Top-line results from Neuraltus’ NP001 Phase 2 study on amyotrophic lateral sclerosis

Children with migraine more likely to have below average school performance

TTP488 slows cognitive decline in patients with mild to moderate Alzheimer's

Scientists hope to unravel mystery of how Borrelia burgdorferi causes Lyme disease

NewYork-Presbyterian/Columbia participates in Symplicity system trial for hypertension

Researchers discover genetic biomarker for age-related hearing loss

BioLineRx intends to conduct interim analysis of BL-1020 Phase II/III trial for schizophrenia

Study finds high internet use by caregivers of children with hydrocephalus

Hypnosis can help cut hot flashes by as much as 74%

Industry Focus eBook - Medical device (1st edition) eBook

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Bioprocess Efficiency with Cell Density Monitoring

Nervous System News and Research

Latest Nervous System News and Research

Industry Focus eBook - Medical device (1st edition) eBook

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Bioprocess Efficiency with Cell Density Monitoring

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