T Cell News and Research

Latest T Cell News and Research

MicroRNAs, EMT and cancer progression

In the April 1 issue of G&D, a research team led by Dr. Marcus Peter (University of Chicago) identifies the microRNA miR-200 as both a powerful indicator and regulator of the epithelial phenotype of cancer cells.

1 Apr 2008

Angina drug ranolazine shows promise for heart rhythm disorders

A recently approved angina drug may also represent a powerful new treatment for a rare hereditary syndrome that places teens at risk for sudden cardiac death, according to research presented at the 57th Annual Scientific Sessions of the American College of Cardiology (ACC) in Chicago.

1 Apr 2008

AIDS, an evolutionary accident?

AIDS, a fatal disease in humans, may partly be the consequence of an evolutionary accident, scientists heard at the Society for General Microbiology's 162nd meeting being held this week at the Edinburgh International Conference Centre.

1 Apr 2008

Genetic test improves artificial fertilization

Polar body diagnosis can make artificial fertilization more successful, according to Katrin and Hans van der Ven and Markus Montag of Bonn University Clinic, writing in the current edition of Deutsches Arzteblatt International (Dtsch Arztebl Int 2008; 105[11]: 190-6).

31 Mar 2008

Gene mutations tied to immune comeback during therapy for HIV-1

A new study by U.S. scientists provides compelling evidence that two genes are linchpins in defining the course of immune restoration in HIV-positive individuals undergoing virus-suppressing therapy.

31 Mar 2008

Expansion of monocyte subset could serve as a biomarker for HIV progressions

An increase in the CD163+/CD16+ monocyte subset could be a biomarker for the progression of HIV disease, according to researchers at Temple University.

31 Mar 2008

Discovery of role of rare gene mutations in schizophrenia

Using an important new method that can be applied in the study of other psychiatric illnesses, scientists at Cold Spring Harbor Laboratory (CSHL) in collaboration with colleagues at the University of Washington (UW) and the National Institute of Mental Health (NIMH), have identified multiple, individually rare gene mutations in people with schizophrenia that may help explain how that devastating illness is caused.

31 Mar 2008

Ebola virus vaccines for humans

One of the world's deadliest diseases, caused by the Ebola virus, may finally be preventable thanks to US and Canadian researchers, who have successfully tested several Ebola vaccines in primates and are now looking to adapt them for human use.

31 Mar 2008

Stem cells from hair follicles may help 'grow' new blood vessels

For a rich source of stem cells to be engineered into new blood vessels or skin tissue, clinicians may one day look no further than the hair on their patients' heads, according to new research published earlier this month by University at Buffalo engineers.

31 Mar 2008

Discovery of new type of retinal cell

Harvard University researchers have discovered a new type of retinal cell that plays an exclusive and unusual role in mice: detecting upward motion.

31 Mar 2008

Saving cancer patients' skin

Becky Sasaki has the quick laugh and easy smile of a woman who continues to thrive despite her four-year wrestling match with lung cancer.

31 Mar 2008

Researchers examine human embryonic stem cell genome

Stem cell researchers from UCLA used a high resolution technique to examine the genome, or total DNA content, of a pair of human embryonic stem cell lines and found that while both lines could form neurons, the lines had differences in the numbers of certain genes that could control such things as individual traits and disease susceptibility.

31 Mar 2008

Umbilical cord blood cell therapy may reduce signs and symptoms of Alzheimer's disease

Targeted immune suppression using human umbilical cord blood cells may improve the pathology associated with Alzheimer's disease, a new study in a mouse model of this currently untreatable neurodegenerative condition reports.

28 Mar 2008

University of Kentucky physician revolutionizes gene research

A dramatic new study published in the most recent issue of Nature questions some of the mechanisms underlying a new class of drugs based on Nobel Prize-winning work designed to fight diseases ranging from macular degeneration to diabetes.

28 Mar 2008

New online stem cell patent database

StemCellPatents.com, an organization dedicated to the advancement of stem cell commercialization, has announced the launch of its newly re-designed free database covering US issued patents dealing with stem cells.

28 Mar 2008

PET confirmed as valuable cancer diagnostic and disease-staging tool

The recent release of data by the National Oncologic PET Registry (NOPR) showing that positron emission tomography (PET) produced scans revealing disease at a molecular level, which then caused physicians to change treatment plans for more than one-third of participating patients, has corroborated decades of nuclear medicine research.

28 Mar 2008

New insights into anti-cancer effects of NSAIDs

Researchers at the National Sun Yat-Sen University and Kaohsiung Medical University, Kaohsiung, Taiwan have revealed a new mechanism by which nonsteroidal anti-inflammatory drugs (NSAIDs) attenuate tumor invasion and metastasis.

28 Mar 2008

New brain cells implicated in machinery of cannabinoid signaling

The researchers said their findings could aid in development of treatments for cannabinoid drug abuse. Also, because so-called "endocannabinoids" produced by brain cells are involved in the neural machinery of pain perception and learning and memory, the findings could help in understanding those processes, said the researchers.

28 Mar 2008

Long-term use of mechanical ventilation contributes to the deterioration of human diaphragm muscle

A new study by University of Pennsylvania School of Medicine shows, for the first time in humans, that ventilators combined with diaphragm disuse contributes to muscle atrophy in the diaphragm in as little as eighteen hours.

28 Mar 2008

Key factor in brain development revealed, offers insight into lissencephaly

In the earliest days of brain development, the brain's first cells - neuroepithelial stem cells - divide continuously, producing a population of cells that eventually evolves into the various cells of the fully formed brain.

28 Mar 2008