T Cell

T-cells are a critical component of the adaptive immune system and are indispensable in protecting humans from pathogenic infections.

Adoptive T Cell Therapy Methodology

Adoptive T cell therapy is a type of immunotherapy that has the ability to target cancer cells through inherent mechanisms of the immune system.

Adoptive T Cell Therapy Applications

T-Cell Metabolism, Immunodeficiency and Human Disease

CAR-T Cell Toxicity and Safety Profiles

Third dose of BNT162b2 vaccine protects against Omicron hospitalizations

A new study assesses the effectiveness of two and three doses of the BNT162b2 vaccine against Omicron-related hospitalizations.

25 Jan 2022

Evaluation of cross-reactive T cell responses between SARS-CoV-2 and common-cold human coronaviruses

A new study investigated SARS-CoV-2 spike protein responses targeted by cross-reactive T cells that were isolated from convalescent COVID-19 individuals along with previously uninfected donors.

25 Jan 2022

Study finds stable T-Cell response against Omicron after mRNA booster vaccination

A new study measured T cell activity in vaccinated individuals and found a third vaccine provided substantial T-cell immunity against the Omicron variant of SARS-CoV-2.

24 Jan 2022

Genetic marker linked to higher risk of death in COVID-19 patients

A new study discusses the importance of single nucleotide polymorphisms in the Rab46 gene as a marker of adverse outcomes in high-risk COVID-19 patients.

23 Jan 2022

Novel SARS-CoV-2 mutations reported in chronic HIV patients

A new study describes the emergence of new SARS-CoV-2 variants in three immunocompromised patients.

23 Jan 2022

Robust BNT162b2 vaccine-induced B and T-cell immunity against early SARS-CoV-2 variants

Researchers describe the state of adaptive immunity following vaccination with the Pfizer-BioNTech BNT162b2 COVID-19 vaccine.

23 Jan 2022

Research shows benefits of hybrid immunity to SARS-CoV-2

Researchers examine the effects of previous SARS-CoV-2 infections on the immunity offered by SARS-CoV-2 vaccination.

20 Jan 2022

Study suggests myeloid cell dysregulation is a driver of COVID-19 severity

Researchers determine the driving factors for disease severity and death due to COVID-19.

17 Jan 2022

Efficacy and safety of mRNA-based SARS-CoV-2 vaccination in immuno-compromised subjects

A team of researchers assessed the immune response after administering a SARS-COV-2 vaccine in immuno-compromised subjects who are potentially at an increased risk to experience severe COVID-19 and inadequate response to SARS-CoV2 vaccination.

17 Jan 2022

Dexamethasone shown to upregulate innate and adaptive immune responses in COVID-19 acute respiratory distress syndrome patients

In a new study, researchers used per protocol bronchoalveolar lavage fluid (BALF) samples after intubation to evaluate the transcriptomic profiles of the local pulmonary host responses during early-stage severe coronavirus disease 2019 (COVID-19) acute respiratory distress syndrome (CARDS), non-COVID-19 ARDS, and sepsis.

17 Jan 2022

Naïve T cells suggested as critical to low mortality of children with COVID-19

A new study discusses how naïve T cells may contribute to lower mortality rates seen in children with COVID-19.

14 Jan 2022

Insignificant homology of SARS-CoV-2 spike sequences to myocarditis-associated antigens

Researchers determine whether sequences within SARS-CoV-2 could lead to an immune response to autoantigens associated with autoimmune myocarditis.

13 Jan 2022

Moffitt experts provide insight on the role of B cell immunity in endometrial cancer

Endometrial cancer is the most common cancer of the female reproductive system. Patients who have active immune responses against cancer cells tend to have better outcomes, but much of what is known focuses on only one type of immune cell called T cells.

13 Jan 2022

Lack of evidence cross-reactive adaptive immune response is mechanism underlying COVID vaccine-induced myocarditis

Recently, the researchers from the USA, in their study published in the journal EBioMedicine, have conducted a sequence identity comparison and 3D protein structure comparison between the SARS-CoV-2 spike protein-derived peptides/protein and myocarditis-associated antigens and have found no significant enrichment in the frequency of spike-derived peptides similar to myocarditis-associated antigens that could have resulted in adaptive autoimmune responses leading to myocarditis.

12 Jan 2022

Cellular and humoral response to SARS-CoV-2 in multiple sclerosis patients using disease-modifying therapies

Researchers examine the effects of disease-modifying therapies implemented for treating multiple sclerosis on the immune response to SARS-CoV-2 infection.

12 Jan 2022

Third dose of mRNA COVID vaccine induces strong immunity in older adults

A new study describes the beneficial effects of a third dose of the COVID-19 mRNA vaccine in strengthening immunity among older adults.

11 Jan 2022

Phase 1 clinical trial shows the safety, feasibility of CAR-M cell therapy for solid tumors

Preliminary findings from Penn Medicine in an ongoing first-in-human clinical trial examining the safety, tolerability and feasibility of chimeric antigen receptor macrophage (CAR-M) has helped to establish the viability of this innovative immunotherapy, which advances the trailblazing scientific discovery of CAR T cell therapy- also pioneered at Penn- for solid cancer tumors and offers a promising new strategy in the fight against cancer.

11 Jan 2022

Hybrid immunity shown to offer sub-optimal protection against SARS-CoV-2 Omicron variant

In a new study, researchers evaluated the neutralizing power of the vaccine against SARS-CoV-2 and vaccine plus infection-induced antibodies against the Omicron variant in a live virus neutralization assay.

10 Jan 2022

Mapping regulatory T-cell populations in COVID-19 patients

In a new study, researchers used mass spectrometry to investigate changes to immune systems, in particular regulatory T-cells (Tregs), in a large cohort of moderate, severe, and critical Japanese coronavirus disease 2019 (COVID-19) patients and healthy controls.

10 Jan 2022

SARS-CoV-2 Omicron a product of offensive evolution with compromised antigenicity

Researchers investigate the relationship between the SARS-CoV-2 Omicron variant and immune system based on self/nonself short constituent sequences.

9 Jan 2022

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T Cell

Overview

Adoptive T Cell Therapy Applications

T-Cell Metabolism, Immunodeficiency and Human Disease

CAR-T Cell Toxicity and Safety Profiles

Latest T Cell News and Research

Third dose of BNT162b2 vaccine protects against Omicron hospitalizations

Evaluation of cross-reactive T cell responses between SARS-CoV-2 and common-cold human coronaviruses

Study finds stable T-Cell response against Omicron after mRNA booster vaccination

Genetic marker linked to higher risk of death in COVID-19 patients

Novel SARS-CoV-2 mutations reported in chronic HIV patients

Robust BNT162b2 vaccine-induced B and T-cell immunity against early SARS-CoV-2 variants

Research shows benefits of hybrid immunity to SARS-CoV-2

Study suggests myeloid cell dysregulation is a driver of COVID-19 severity

Efficacy and safety of mRNA-based SARS-CoV-2 vaccination in immuno-compromised subjects

Dexamethasone shown to upregulate innate and adaptive immune responses in COVID-19 acute respiratory distress syndrome patients

Naïve T cells suggested as critical to low mortality of children with COVID-19

Insignificant homology of SARS-CoV-2 spike sequences to myocarditis-associated antigens

Moffitt experts provide insight on the role of B cell immunity in endometrial cancer

Lack of evidence cross-reactive adaptive immune response is mechanism underlying COVID vaccine-induced myocarditis

Cellular and humoral response to SARS-CoV-2 in multiple sclerosis patients using disease-modifying therapies

Third dose of mRNA COVID vaccine induces strong immunity in older adults

Phase 1 clinical trial shows the safety, feasibility of CAR-M cell therapy for solid tumors

Hybrid immunity shown to offer sub-optimal protection against SARS-CoV-2 Omicron variant

Mapping regulatory T-cell populations in COVID-19 patients

SARS-CoV-2 Omicron a product of offensive evolution with compromised antigenicity

Novel gene therapy for diseased muscle fiber repair

PFAS found in high levels in anti-fogging sprays

Could heart rate be a risk factor for dementia?

T Cell

Overview

Latest T Cell News and Research

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