T Cell News and Research

Latest T Cell News and Research

Combination of RAS inhibition and immunotherapy provides breakthrough for pancreatic cancer

Adding immunotherapy to a new type of inhibitor that targets multiple forms of the cancer-causing gene mutation KRAS kept pancreatic cancer at bay in preclinical models for significantly longer than the same targeted therapy by itself, according to researchers from the Perelman School of Medicine at the University of Pennsylvania and Penn Medicine's Abramson Cancer Center.

14 Mar 2025

Study highlights the role of ELF4 as a key transcription factor in development, immunity, and oncology

ELF4, a transcription factor belonging to the ETS family, has emerged as a pivotal regulator in cell differentiation, immune system function, and cancer progression. This newly published review underscores its molecular complexity and clinical significance, shedding light on its dual role in tumor suppression and oncogenesis.

11 Mar 2025

New test could predict life-threatening side effects of cancer immunotherapy

Medical researchers in Japan have discovered a way to predict a potentially life-threatening side effect of cancer immunotherapy before it occurs.

10 Mar 2025

New stem cell-based vascular grafts could revolutionize cardiac surgery

Scientists at the Wisconsin National Primate Research Center (WNPRC) and the Morgridge Institute for Research at the University of Wisconsin–Madison have been at the forefront of stem cell research and regenerative biology since James Thomson isolated the first human embryonic stem cell in 1998.

10 Mar 2025

Advancements in molecular diagnostics for hematopoietic and lymphocytic neoplasms

Hematopoietic and lymphocytic neoplasms (HLNs) are a diverse group of malignancies affecting blood and lymphatic systems, with outcomes varying from manageable conditions to fatal diseases.

27 Feb 2025

LabGenius Therapeutics appoints three experts to its team of scientific advisors

Pioneering therapeutic antibody optimization, LabGenius Therapeutics utilizes advanced technologies to improve drug development and clinical translation.

From LabGenius 27 Feb 2025

Study unravels the complex interplay of the UPS in cancer development and treatment

A new review published in Genes & Diseases explores the pivotal role of the ubiquitin-proteasome system (UPS) in regulating the tumor microenvironment (TME) and driving cancer progression. The study provides novel insights into how ubiquitination and deubiquitination impact tumor cells, immune responses, and potential therapeutic strategies for cancer treatment.

24 Feb 2025

Interferon gamma persistence offers clues to Long COVID and potential therapies

SARS-CoV-2 triggers the production of the antiviral protein IFN-γ, which is associated with fatigue, muscle ache and depression. New research shows that in Long COVID patients, IFN-y production persists until symptoms improve, highlighting a potential biomarker and a target for therapies.

22 Feb 2025

FDA ensures blood safety through five layers of safeguards

Every day, hospitals throughout the U.S. transfuse blood or blood components, such as platelets, to save the lives of people who are in car crashes, and victims of fires and other emergencies.

20 Feb 2025

Cancer-free for 18 years: CAR-T therapy sets new milestone in neuroblastoma treatment

A groundbreaking study in Nature Medicine reveals that GD2 CAR-T cell therapy can lead to long-term remission in children with neuroblastoma, with one patient remaining cancer-free for over 18 years.

17 Feb 2025

Scottish Medicines Consortium approves Libtayo as second-line treatment for advanced cervical cancer

Regeneron UK Limited today announced that the Scottish Medicines Consortium (SMC) has accepted Libtayo® (cemiplimab) for use on the National Health Service as a second-line monotherapy treatment for adults with recurrent or metastatic cervical cancer and disease progression on or after platinum-based chemotherapy, irrespective of PD-L1 expression level or tumor histology.

14 Feb 2025

The growing list of human viruses: Are we prepared for the next outbreak?

Researchers review the ever-growing list of human viruses, examining their diversity, transmission pathways, and the urgent need for prevention and global surveillance.

12 Feb 2025

Study identifies vitamin E succinate as key to tumor growth control

High levels of fat mass and obesity-associated protein (FTO) have been linked to increased tumor growth and resistance to immunotherapy.

12 Feb 2025

New immune map uncovers key pancreatic cancer insights

Researchers determine a complex immune infiltrate pattern based on a newly constructed immune map developed using pancreatic cancer cells.

12 Feb 2025

AIM Vaccine submits mRNA RSV vaccine for FDA clinical trials

AIM Vaccine Co., Ltd., a leading PRC vaccine company, announced today that its independently developed mRNA RSV (respiratory syncytial virus) vaccine has recently been submitted for clinical trials to the U.S. Food and Drug Administration (FDA).

10 Feb 2025

Understanding infection risks in pediatric hematopoietic stem cell transplantation

Hematopoietic stem cell transplantation (HSCT) is a vital treatment for both malignant and non-malignant disorders in pediatric patients.

7 Feb 2025

How lymphoid tissues protect against viral infections

Researchers explore the cellular and molecular adaptations associated with human secondary lymphoid tissue in adults during viral infection.

7 Feb 2025

Neoantigen vaccine sparks powerful immune defense against kidney cancer

A personalized neoantigen cancer vaccine generated strong immune responses in renal cell carcinoma patients, leading to long-lasting T cell expansion and no disease recurrence after 40 months.

6 Feb 2025

New study confirms CAR T cell therapy does not cause secondary cancers

Within a large group of more than 700 patients treated with CAR T cell therapy, researchers found no evidence that the therapy itself caused any type of secondary cancer in the modified T cells, according to new analysis reported today in Nature Medicine from the Perelman School of Medicine at the University of Pennsylvania and Penn Medicine's Abramson Cancer Center.

3 Feb 2025

The CAR T Veteran: A Journey of Resilience, Remission, and Advocacy

Laurie Adami's experience with CAR T-cell therapy highlights its potential in treating Non-Hodgkin Lymphoma, emphasizing the importance of patient advocacy.

3 Feb 2025

T Cell News and Research

Latest T Cell News and Research

Combination of RAS inhibition and immunotherapy provides breakthrough for pancreatic cancer

Study highlights the role of ELF4 as a key transcription factor in development, immunity, and oncology

New test could predict life-threatening side effects of cancer immunotherapy

New stem cell-based vascular grafts could revolutionize cardiac surgery

Advancements in molecular diagnostics for hematopoietic and lymphocytic neoplasms

LabGenius Therapeutics appoints three experts to its team of scientific advisors

Study unravels the complex interplay of the UPS in cancer development and treatment

Interferon gamma persistence offers clues to Long COVID and potential therapies

FDA ensures blood safety through five layers of safeguards

Cancer-free for 18 years: CAR-T therapy sets new milestone in neuroblastoma treatment

Scottish Medicines Consortium approves Libtayo as second-line treatment for advanced cervical cancer

The growing list of human viruses: Are we prepared for the next outbreak?

Study identifies vitamin E succinate as key to tumor growth control

New immune map uncovers key pancreatic cancer insights

AIM Vaccine submits mRNA RSV vaccine for FDA clinical trials

Understanding infection risks in pediatric hematopoietic stem cell transplantation

How lymphoid tissues protect against viral infections

Neoantigen vaccine sparks powerful immune defense against kidney cancer

New study confirms CAR T cell therapy does not cause secondary cancers

The CAR T Veteran: A Journey of Resilience, Remission, and Advocacy

Immunology eBook

Leveraging the Radian ASAP in standard casework

A journey through science, software, and innovation: Insights from the Bruker software team

CellVoyant's AI-Powered Vision for the Future of Cell Therapy

T Cell News and Research

Latest T Cell News and Research

Immunology eBook

Leveraging the Radian ASAP in standard casework

A journey through science, software, and innovation: Insights from the Bruker software team

CellVoyant's AI-Powered Vision for the Future of Cell Therapy

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