What is Epididymitis?

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Epididymitis is a health condition involving inflammation of the epididymis, the tube that stores and transports sperm in the back of the testicles. Men of any age can be affected by the condition, but it is most common in young men aged between 19 and 35 years and frequently causes hospitalization in the military.

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Approximately 1 in 1000 men is affected by epididymitis each year, making the condition the most common cause of scrotal inflammation. It is among the top five most diagnosed urologic condition for men aged between 18 and 50 years.

Acute epididymitis usually occurs in young men aged between 19 and 35 years but may affect men of any age. Chronic epididymitis is often under-diagnosed for several years, and the average age of presentation is approximately 50 years. Epididymitis is uncommon in children, although it can occur.


There are various possible causes of epididymitis, including:

  • Sexually transmitted infections (STIs) such as chlamydia and gonorrhea
  • Urinary tract infection (UTI)
  • Enlarged prostate
  • Use of catheter
  • Surgery to the prostate, bladder or groin region
  • Structural abnormalities of the urinary tract
  • Groin injury

STIs are the most common cause, particularly in young men between the age of 19 and 35 that have engaged with multiple sexual partners without using condoms.


The symptoms of epididymitis tend to present gradually and worsen over time if left untreated. The symptoms may include:

  • Inflammation (swollen, red and warm) scrotum
  • Pressure or pain in the testicles, usually unilateral
  • Enlarged lymph nodes in the groin
  • Pain with urination or bowel movements
  • Increased frequency and urgency of urination
  • Pain with intercourse and ejaculation
  • Discharge from penis
  • Blood in semen
  • Pain in the abdominal and pelvic region
  • Low fever and chills

The specific symptoms depend on the cause of the condition. For example, epididymitis caused by an STI is more likely to be associated with a discharge from the penis, whereas a UTI is more likely to be associated with increased pain, frequency and urgency of urination.


When a patient presents with symptoms that may be indicative of epididymitis, the first step in diagnosing the condition is to conduct a physical exam to check for signs and symptoms, such as inflammation of the testicles or lymph node enlargement. This may also include a rectal examination to check for prostate enlargement.

There are a number of other tests that may then be conducted, including:

  • STI screening tests
  • Complete blood count (CBC)
  • Urinalysis and culture
  • Doppler ultrasound imaging
  • Testicular nuclear medicine scan

It is important to distinguish epididymitis from other similar health conditions such as testicular torsion in the diagnostic process. Testicular torsion usually presents more suddenly and is associated with severe consequences if not treated immediately.


The treatment of epididymitis is based on the resolution of the underlying infection, which leads to an improvement in symptoms.

A course of antibiotics is usually recommended, in addition to analgesic and anti-inflammatory medication to ease the immediate symptoms. Other techniques to relieve the pain include cold therapy and elevation of the scrotum. Additionally, it is important that patients rest and allow their bodies to fully recover. Abstaining from sexual intercourse is recommended during treatment to prevent a recurrence of the infection.

With appropriate treatment, the pain associated with epididymitis usually improves within 1-3 days. However, some symptoms may take several months to resolve.

In some cases, further treatment techniques are required. This may include draining of pus with a needle if an abscess forms or surgical procedures in severe cases.


Further Reading

Last Updated: Apr 6, 2021

Yolanda Smith

Written by

Yolanda Smith

Yolanda graduated with a Bachelor of Pharmacy at the University of South Australia and has experience working in both Australia and Italy. She is passionate about how medicine, diet and lifestyle affect our health and enjoys helping people understand this. In her spare time she loves to explore the world and learn about new cultures and languages.


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  1. Young Adson Young Adson Korea says:

    I had epididymitis for about 3 years. It's uncomfortable to sit for a long time because of the enlarged testicle. I had to urinate frequently during the day. It's really the darkest time for me. I'd tried several antibiotics but none helped. I also tried herbal remedies. The one that helped me get rid of the infection was called diuretic and anti-inflammatory pill. I was so happy to know I was cured completely.

The opinions expressed here are the views of the writer and do not necessarily reflect the views and opinions of News Medical.
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