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How to make hybridoma-based antibody discovery more efficient

Cyto-Mine® tackles the time-consuming and labor-intensive challenges of screening extensive cell populations for rare, antigen-specific antibody-secreting cells during antibody discovery. It transforms the traditional multi-step process into a seamless, fully-integrated workflow that can be completed in just one day.

hybridoma-based antibody

Image Credit: Fluidic Sciences and Sphere Bio

The past 20 years have witnessed an extraordinary rise in monoclonal antibody-based therapeutics, with over 80 mAbs now approved for clinical use.

As these antibody-based therapies progress through clinical studies and gain approval at an accelerated pace, the growing competition and success of these treatments place increasing pressure on biopharmaceutical companies to expedite the development of new biologics.

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hybridoma-based antibody

Image Credit: Fluidic Sciences and Sphere Bio

About Fluidic Sciences and Sphere Bio

Fluidic Sciences develops transformative in‑solution technologies for protein interaction analysis. Its flagship Fluidity One‑M instrument leverages Microfluidic Diffusional Sizing (MDS) to measure binding affinity, stoichiometry, size, and concentration without immobilization - directly in complex backgrounds such as serum, plasma, and lysate.

Sphere Bio is a brand of Fluidic Sciences. Its technology develops and manufactures single‑cell analysis and monoclonality assurance systems that enable researchers to find, analyze, and isolate the most valuable cells with speed and precision. Its proprietary picodroplet microfluidics and Cyto‑Mine® Chroma multiplexing platform power applications across antibody discovery, cell line development, cell engineering, and cell therapy.


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